Results 101 to 110 of about 77,462 (276)

Adverse radiation effect in the brain during cancer radiotherapy

Journal of Radiation and Cancer Research, 2017
Adverse radiation effect (ARE) in the brain is the reactive inflammation, vasculitis, and necrosis that occurs as a complication of radiotherapy. There are two main categories of ARE that result in vasogenic cerebral edema: first, a residual irritant ...
Andrew J Fabiano, Dheerendra Prasad, Jingxin Qiu   +2 more
doaj   +1 more source

Nano‐Enabled Systemic Delivery of STING Agonist by Engineered Silicasome for Potent Antitumor Immunotherapy

Advanced Science, EarlyView.
Engineered mesoporous silica nanoparticles (Silicasomes) enable systemic delivery of the STING agonist ADU‐S100, overcoming the instability and toxicity that limit cyclic dinucleotides to local administration. By enhancing tumor accumulation, activating systemic antitumor immunity, and remodeling the tumor immune microenvironment, these nanoparticles ...
Wenjing Zhou, Yuting Li, Xudong Sun, Honghong Yang, Xiayu Shi, Lijia Yao, Jinhong Jiang, Erli Wang, Haoyang Wang, Yi Wei, Xiangsheng Liu   +10 more
wiley   +1 more source

he thermal conductivity of cortical and cancellous bone [PDF]

, 2018
Surgical interventions close to vulnerable structures, such as nerves, require precise handling of surgical instruments and tools. These tools not only pose the risk of mechanical damage to soft tissues, but they also generate heat, which can lead to ...
A Feldmann, P Wili, Wili, Patrik, G Maquer, null null, P Zysset, Feldmann, Arne Niklas, Maquer, Ghislain Bernard, Zysset, Philippe   +8 more
core   +1 more source

Mechanically Robust Biodegradable Stents With Theragenerative Vascular Responses via Combined 3D Printing and Janus Nanoengineering

Advanced Science, EarlyView.
This work introduces a theragenerative 3D‐printed biodegradable stent with Janus nanoarchitecture for spatially controlled vascular healing. A luminal tantalum ion–implanted surface accelerates endothelialization and hemocompatibility, while an abluminal sirolimus/poly‐L‐lactic acid–tantalum layer provides sustained drug release and suppresses smooth ...
Jong Hwa Seo, Dong‐Sung Won, Hyun Lee, Seojoon Bang, Hyeong Seok Kang, Ju Yeong Gwon, Chan Ho Moon, Ji Won Kim, Yubeen Park, Minho Kang, Dong Yun Lee, Donghyun Lim, Kisuk Yang, Gi Doo Cha, Soo‐Hong Lee, Tae‐Sik Jang, Seokbeom Kim, Jun‐Kyu Park, Jung‐Hoon Park, Hyun‐Do Jung   +19 more
wiley   +1 more source

Nanozymes for Advanced Hemoglobin‐Based Oxygen Carriers: Applications in Blood Substitution, Wound Healing, Antitumor Therapy, and Beyond

Advanced Science, EarlyView.
This review explores how hemoglobin‐based oxygen carriers (HBOCs) combined with nanozymes create multifunctional materials that deliver oxygen while maintaining redox homeostasis. Beyond artificial blood substitutes, these constructs enable wound healing with light‐triggered oxygen release, cancer therapy through enhanced oxygenation and reactive ...
Despoina Douka, Ana María Pablo‐Sainz‐Ezquerra, Eva Jakljevič, Niki Ktena, Leticia Hosta‐Rigau   +4 more
wiley   +1 more source

Topical erythropoietin in the management of scleral necrosis: a narrative review

Therapeutic Advances in Ophthalmology
Scleral necrosis is a rare but severe complication caused by various etiologies. The main therapeutic approach is topical and systemic medical treatment. Surgical interventions may be indicated in unresponsive cases.
Kosar Namakin, Sara Ziayifard, Zahra Tahmasbi, Atefeh Jafarian, Sepehr Feizi   +4 more
doaj   +1 more source

Construction of a MOF‐Based Snap‐Top Delivery Nanosystem for Powerful Dual‐Responsive Synergistic Colitis Treatment

Advanced Science, EarlyView.
A snap‐top delivery nanosystem based on an azobenzene metal–organic framework achieves targeted release of 6‐mercaptopurine via acid‐stable frameworks and hypoxia/pH dual‐responsive β‐cyclodextrin gates. This multifunctional platform integrates three synergistic mechanisms: precision drug delivery to inflammatory sites, intrinsic antioxidant properties
Xin Li, Miao Xu, Heran Li, Huan Jiang, Xin Wang, Lianjun Ma, Ying‐Wei Yang   +6 more
wiley   +1 more source

Tibiotalocalcaneal joint resection using a conical ultrasonic debridement probe

Foot & Ankle Surgery: Techniques, Reports & Cases
Thermal necrosis and neurovascular injury both contribute to complications associated with saw and rotary burr joint resection techniques. Ultrasonic debridement is atraumatic and purportedly isolates necrotic tissue while sparing living tissues of ...
Trevor S. Page, BS, Evan W. Schneider, BA, Robert M. Joseph, DPM, PhD, FACFAS   +2 more
doaj   +1 more source

Catastrophic Thermal Corneoscleral Injury Treated with Transplantation of Donor Scleral Graft

Case Reports in Ophthalmology, 2017
Background: The aim of this study is to report a patient with senile cataract developing severe thermal corneoscleral injury during phacoemulsification, which was treated with a donor scleral graft.
Satoru Kase, Takeshi Ohguchi, Susumu Ishida   +2 more
doaj   +1 more source

Solar‐induced dorsal skin necrosis in sheep

, 2019
Background: Solar-induced thermal burns of dark skin over the dorsum have been reported in dogs, sheep and a pig. Objectives: This report describes an outbreak of solar-induced thermal burns over the dorsal skin of criollo and Texel sheep in Uruguay ...
Francisco A. Uzal, Romero, Agustín, Uzal, Francisco A., Tarigo, Laura, Laura Tarigo, Juan A. García, Fernando Dutra, García, Juan Agustín, Dutra, Fernando, Agustín Romero, Verena K. Affolter, Affolter, Verena K.   +11 more
core   +1 more source