Results 51 to 60 of about 77,462 (276)

Predicting neuropathy and reactions in leprosy at diagnosis and before incident events. Results from the INFIR cohort study [PDF]

, 2009
BackgroundLeprosy is a disease of skin and peripheral nerves. The process of nerve injury occurs gradually through the course of the disease as well as acutely in association with reactions. The INFIR (ILEP Nerve Function Impairment and Reactions) Cohort
Smith, W Cairns S, Sundar Rao, P.S.S., Diana N J Lockwood, Einar P Wilder-Smith, Rao, P S S Sundar, Van Brakel, W.H., Das, Loretta, W Cairns S Smith, Jadhav Rupendra, Jadhav, R., Wilder-Smith, E.P., Barkataki, P., Wim H van Brakel, Sujai Suneetha, P S S Sundar Rao, Smith, W., Lockwood Diana N. J., Nicholls, P.G., Barkataki Pramila, Wilder-Smith, Einar P., Lockwood, D.N., Smith, W. Cairns S., Lockwood, Diana N J, Lavanya Suneetha, Pramila Barkataki, Suneetha Lavanya, Jadhav, Rupendra, Smith, W.C.S., Nicholls Peter G., Sundar Rao, PSS, Peter G Nicholls, Suneetha, L., Das Loretta, Smith W. Cairns S., Loretta Das, Das, L., van Brakel, Wim H., Lockwood, Diana NJ, Lockwood, Diana N.J., Wilder-Smith, Einar P, Suneetha, Sujai, Lockwood, D.N.J., Suneetha Sujai, Brakel, W.H. van, Suneetha, Lavanya, van Brakel, Wim H, Sundar Rao P. S. S., van Brakel Wim H., Suneetha, S., Wilder-Smith Einar P., Rao, P.S.S.S., Nicholls, Peter G, Rupendra Jadhav, Barkataki, Pramila   +53 more
core   +1 more source

Genipin‐Crosslinked, Silane‐Anchored 3D Tumor–Stroma Microtissues for High‐Content On‐Chip Drug Testing

Advanced Healthcare Materials, EarlyView.
We describe a microfluidic tumor‐stroma co‐culture model, engineered to resist collagen‐hydrogel contraction driven by fibroblast activity. Surface silanization with APTES covalently anchors the matrix to the chip, while Genipin crosslinking progressively increases stiffness and elasticity without harming cells. This supports >10 days of co‐culture and
Doriane Le Manach, Reza Kowsari‐Esfahan, Emilia Reszczyńska, Philippe Nghe, Matthias Nees   +4 more
wiley   +1 more source

Wound trauma mediated inflammatory signaling attenuates a tissue regenerative response in MRL/MpJ mice

Journal of Inflammation, 2010
Background Severe trauma can induce pathophysiological responses that have marked inflammatory components. The development of systemic inflammation following severe thermal injury has been implicated in immune dysfunction, delayed wound healing, multi ...
Elster Eric A, Anam Khairul, Amare Mihret F, Zins Stephen R, Davis Thomas A   +4 more
doaj   +1 more source

Serum antioxidants as predictors of the adult respiratory distress syndrome in septic patients [PDF]

, 1993
Adult respiratory distress syndrome (ARDS) can develop as a complication of various disorders, including sepsis, but it has not been possible to identify which of the patients at risk will develop this serious disorder.
Moore, Frederick A., Parsons, Polly E., Repine, John E., Leff, Jonathan A., Jochum, Marianne, Fritz, Hans, Moore, Eugene E., McCord, Joe M., Taniguchi, Naoyuki, Day, Caroline E.   +9 more
core   +1 more source

Thermal necrosis assisted dental implant removal: a 3-dimensional finite element analysis

, 2022
Dental implants are a common and popular alternative for the replacement of missing teeth. A low degree of regulated thermal necrosis at the bone-implant interface can help avoid the loss of healthy tissue and the risk of damage caused by the removal of ...
Agarwal, Abhilash, Swain, Utkarsh, Prabhu, Nayana, Jaladi, Gautam, Bhat, Ritesh, Patil, Vathsala, Kowshik, Suhas, Kumar, Krishna   +7 more
core   +1 more source

Decellularized Extracellular Matrix (dECM) in Tendon Regeneration: A Comprehensive Review

Advanced Healthcare Materials, EarlyView.
Decellularized Extracellular Matrix (dECM) offers a promising solution by replicating the native tendon microenvironment and promoting regeneration. This review highlights advances in the decellularization methods, as well as their integration with emerging technologies and translational progress in tendon tissue engineering.
Kumaresan Sakthiabirami, Yeonwoo Park, Seong Kyeong Jo, Min Hee Kim, Jae Hwang Song   +4 more
wiley   +1 more source

The Ile585Val TRPV1 variant is involved in risk of painful knee osteoarthritis [PDF]

, 2011
Objective To assess if a coding variant in the gene encoding transient receptor potential cation channel, subfamily V, member 1 ( TRPV1 ) is associated with genetic risk of painful knee osteoarthritis (OA). Methods The Ile585Val TRPV1 variant encoded
K. R. Muir, Lories, RJ, C. Cooper, Hart, DJ, D. J. Hart, W. Zhang, Dennison, Elaine M., Arden, Nigel, S. A. Doherty, Chapman, Victoria, Cicuttini, FM, Valdes, Ana M., Doherty, Sally A., Muir, Kenneth R., Vaughn, Frances L., T. D. Spector, Zhang, Weiya, Laslett, LL, Doherty, SA, Arden, N., Lories, Rik J., Chapman, V, Jones, Graeme, A. Soni, Muir, KR, P. Leaverton, V. Chapman, Leaverton, Paul, Spector, T. D., Arden, Nigel K., Jones, G, Cicuttini, Flavia M., Wilde, Gert De, Muir, Kenneth, Doherty, M, G. Jones, Hart, Deborah J., Wheeler, M, R. A. Maciewicz, Leaverton, P, Cooper, Cyrus, N. K. Arden, Valdes, AM, G. De Wilde, Arden, NK, Laslett, Laura L., Vaughn, FL, F. L. Vaughn, De Wilde, G, Zhang, W, A. M. Valdes, Maciewicz, Rose A., Maciewicz, RA, Spector, Tim D., Wheeler, Margaret, Dennison, EM, Spector, TD, M. Doherty, Cooper, C, R. J. Lories, M. Wheeler, Soni, Anushka, E. M. Dennison, F. M. Cicuttini, L. L. Laslett, De Wilde, Gert, Soni, A, Hart, Deborah J.; id_orcid, Doherty, Michael   +68 more
core   +1 more source

Cold Atmospheric Plasma‐Activated Decellularized Extracellular Matrix Gel as a Tumor‐Infiltrating Immunoactivation Platform for Post‐Surgical Cancer Immunotherapy

Advanced Materials, EarlyView.
An injectable cold atmospheric plasma‐activated decellularized tumor extracellular matrix hydrogel is introduced as a post‐surgical immunoactivation platform. The engineered gel attracts residual tumor cells and induces immunogenic cell death, reshaping the tumor microenvironment and eliciting systemic antitumor immunity. In combination with checkpoint
Tianxu Fang, Mo Chen, Yueyang Deng, Tianqin Ning, Tianwen Luo, Guojun Chen   +5 more
wiley   +1 more source

A review of high-intensity focused ultrasound as a novel and non-invasive interventional radiology technique

Journal of Interventional Medicine, 2022
High-intensity focused ultrasound (HIFU) is a non-invasive interventional radiology technology, which has been generally accepted in clinical practice for the treatment of benign and malignant tumors.
Ruihong Yao, Jihong Hu, Wei Zhao, Yongde Cheng, Chaofan Feng   +4 more
doaj   +1 more source

Mechanically Spatio‐Chimeric Fibrin Assembly Enables Vascular‐Integrated Muscle Reconstruction for Volumetric Muscle Loss Repair

Advanced Materials, EarlyView.
SPARC (spatio‐chimeric, plasma‐based, anisotropic, and shear‐responsive construct) that integrates myogenic and vascular microenvironments within a single construct. The dual‐modulus matrix directs aligned myotube formation and endothelial network development, enabling a vascularized muscle implant that seamlessly anastomoses with host tissue and ...
Su Hyun Jung, Minjun Kim, Da‐Yoon Kim, Min Kyu Kim, Sieun Lee, Yoonhee Jin, Joo H. Kang   +6 more
wiley   +1 more source