Results 41 to 50 of about 1,079,849 (348)

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

A Molecular Dynamics Study on the Effects of Nanostructural Clearances on Thermal Resistance at a Lennard-Jones Liquid-Solid Interface

Journal of Thermal Science and Technology, 2011
The effects of the surface structures and the surface structural clearances at the nanometer scale on the thermal resistance at a Lennard-Jones liquid-solid interface, as well as the self-diffusion behaviors of liquid molecules, were investigated ...
Masahiko SHIBAHARA, Kiyoshi TAKEUCHI
doaj   +1 more source

Silicon switching transistor with high power and low saturation voltage [PDF]

, 1973
Assembly of two individually encapsulated silicon-chip transistors produces silicon power-transistor that has low electrical resistance and low thermal impedance.
Ferree, H., Stonebraker, E., Stoneburner, D.   +2 more
core   +1 more source

Effect of Electron-Phonon Coupling on Thermal Transport across Metal-Nonmetal Interface - A Second Look

, 2015
The effect of electron-phonon (e-ph) coupling on thermal transport across metal-nonmetal interfaces is yet to be completely understood. In this paper, we use a series of molecular dynamics (MD) simulations with e-ph coupling effect included by Langevin ...
Luo, Tengfei, Wu, Xufei
core   +1 more source

Thermal boundary resistance from transient nanocalorimetry: a multiscale modeling approach [PDF]

, 2016
The Thermal Boundary Resistance at the interface between a nanosized Al film and an Al_{2}O_{3} substrate is investigated at an atomistic level. A room temperature value of 1.4 m^{2}K/GW is found.
Banfi, Francesco, Caddeo, Claudia, Colombo, Luciano, Ferrini, Gabriele, Giannetti, Claudio, Melis, Claudio, Ronchi, Andrea, Rurali, Riccardo   +7 more
core   +2 more sources

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Non-spore-forming thermoduric bacteria vary considerably in thermal resistance in milk media between strains from the same genus

Journal of Dairy Science
: Thermoduric bacteria, defined as those that survive temperatures considerably above their maximum growth temperature, are enumerated in milk using the laboratory pasteurization count (LPC) test.
Caroline Motzer, Martin Wiedmann, Nicole Martin   +2 more
doaj   +1 more source

Wetsuit Thermal Resistivity Measurements

Sensors
In recent years, attention to the realization and characterization of wetsuits for scuba diving and other sea sports or activities has increased. The research has aimed to establish reliable and standardized measurement methods to objectively assess wetsuit quality, particularly focusing on their mechanical and thermal properties.
Gianluca Crotti, Roberto Cantù, Stefano Malavasi, Gianluca Gatti, Christian Laurano, Cesare Svelto   +5 more
openaire   +3 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Research of heat conductivity of quartz material

Қарағанды университетінің хабаршысы. Физика сериясы
In the article the results of a study of heat conductivity and thermal resistance of quartz-containing materials were presented. The object of the study was a quartz mineral from the Aktas deposit, located in the Ulytau district of the Karaganda region.
A.K. Хасенов, Г.A. Булкаировa, Б.Р. Нусупбеков, E.Р. Шрагер, Д.Ж. Карабековa, M.М. Болатбекова, Е.A. Жолдасбек   +6 more
doaj   +1 more source