Results 61 to 70 of about 32,150 (294)

Modelling Residential Outdoor Thermal Sensation in Hot Summer Cities: A Case Study in Chongqing, China

open access: yesBuildings, 2022
Exposure to extreme heat is a significant public health problem and the primary cause of weather-related mortality, which can be anticipated by accurately predicting outdoor thermal sensation.
Ying Liu   +5 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Determinación de los intervalos de confort y estrés térmico para espacios abiertos en la ciudad de Maringá (PR), Brasil, utilizando el índice PET

open access: yesDesenvolvimento e Meio Ambiente, 2019
Prediction models of thermal comfort in open spaces are considered a fundamental tool in neighborhood planning, as well as in open space design within urban areas. However, most of these indices were developed for cold climates.
Mirna Milena Aquino   +2 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

An integrated thermal sensation scale for estimating thermal strain in water

open access: yes
International audienceAcceptable definitions of thermal sensation for cold and hot water immersion do not exist. The use of subjective thermal sensation scales remains unsolved with broad psycho-physiological, and semantic implications.
Douka, Angeliki   +7 more
core   +2 more sources

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Thermal sensation of children and its predictive evaluation method in Indonesia’s dry season

open access: yesJournal of Asian Architecture and Building Engineering
There is a discrepancy between children’s thermal sensation in hot-humid climates near the equator and conventional thermal comfort indexes, such as the predicted mean vote (PMV).
Masaya Kitaura   +3 more
doaj   +1 more source

ASSESSMENT OF THERMAL SENSATION OF RESIDENTS IN THE SOUTHERN GREAT PLAIN, HUNGARY [PDF]

open access: yesAerul şi Apa: Componente ale Mediului, 2014
This study examines the subjective thermal sensation characteristics of people living in Szeged, in the Southern Hungarian Great Plain. Micrometeorological measurements were conducted with two mobile stations in six urban public spaces during 70 days ...
KOVÁCS A.   +2 more
doaj  

Thermal sensations of secondary schoolchildren in summer [PDF]

open access: yesJournal of Hygiene, 1973
SUMMARYSummer thermal sensations of secondary schoolchildren in England are compared with those earlier published for winter. Heat stress, contrary to expectation, is seen to decrease during the warm months, and neutrality is found to increase by some 6° F.
openaire   +4 more sources

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