Results 31 to 40 of about 74,346 (217)

Improving the process of layerwise laser welding of metal parts by controlling residual stresses

Известия высших учебных заведений. Поволжский регион:Технические науки, 2022
Background. Layerwise laser welding of metal parts allows you to get a weld in layers. As a result of the heating of the surface, thermal stresses sharply increase, caused by a non-stationary temperature field.
T.N. Ivanova, A.Yu. Muyzemnek
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Laser Forming of Austenitic Stainless and Manganese Carbon Steels [PDF]

Журнал інженерних наук, 2016
Laser forming has several advantages compared to the machining methods of workpieces. This method avoids sringback effect, thinning of the material in the processing zone. It can form brittle, tough, elastic material, sheets of considerable low thickness
O. D. Kahlyak, O. O. Honcharuk, N. O. Melnik-Kahlyak, M. O. Sklyar   +3 more
doaj  

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

The Impact of Conventional Power Block Startup Procedures on the Fatigue Behavior of Drum Materials

Energies, 2022
Varying demands for electricity within the energy sector require the modification of operating modes to ensure both an uninterrupted electricity supply and the upholding of safety standards. This paper presents a method for the prediction of drum fatigue
Jerzy Okrajni, Krzysztof Wacławiak, Mariusz Twardawa, Grzegorz Junak   +3 more
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

A study of thermal effort during half-hour start-up and shutdown of a 400 MW steam power plant spherical Y-pipe

Case Studies in Thermal Engineering, 2020
The subject of considerations is a spherical Y-pipe made of the 91 steel, which is an element of a coal-fired power plant unit working with a 18K370 turbine.
Bartosz Kraszewski
doaj   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source