Results 91 to 100 of about 991,745 (315)

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Desenvolvimento vegetativo e reprodutivo de cultivares de trigo e sua associação com a emissão de folhas Vegetative and reproductive development of wheat cultivars and its association with leaf appearance

open access: yesCiência Rural, 2009
O objetivo deste estudo foi determinar a relação da duração das fases vegetativa, reprodutiva e total do ciclo de desenvolvimento com o número final de folhas e com a velocidade de aparecimento de folhas no colmo principal, em cultivares brasileiras de ...
Lidiane Cristine Walter   +4 more
doaj  

Desenvolvimento vegetativo de duas cultivares de oliveira na fase de muda Vegetative development of two olive cultivars in seedling phase

open access: yesCiência Rural, 2012
O desenvolvimento de plantas, influenciado pela temperatura do ar, pode ser estimado através do conceito de filocrono, definido como o intervalo de tempo entre o surgimento sucessivo de folhas em uma haste, sendo o tempo expresso em °C dia e o filocrono ...
Priscila Maria Martins Lisboa   +4 more
doaj   +1 more source

On the thermal buffering of naturally ventilated buildings through internal thermal mass

open access: yes
In this paper we examine the role of thermal mass in buffering the interior temperature of a naturally ventilated building from the diurnal fluctuations in the environment.
Woods, A. W. andy; BPI;, Holford, J. M.
core   +1 more source

Thermal Performance of a Multi-Axis Smoothing Cell [PDF]

open access: yes, 2011
Multi Axis Robots have traditionally been used in industry for pick and place, de-burring, and welding operations. Increasing technological advances have broadened their application and today robots are increasingly being used for higher precision ...
Georgiou, Charalambos Andrew
core  

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

open access: yesMolecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht   +3 more
wiley   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

Temperature and storage time strongly affect the germination success of perennial Euphorbia species in Mediterranean regions

open access: yesEcology and Evolution, 2019
This study aims to explore the effect of environmental factors (temperature, light, storage time) on germination response and dormancy patterns in eight Mediterranean native wildplants, belonging to the Euphorbia L. genus.
Antonia Cristaudo   +4 more
doaj   +1 more source

Base temperature and simulation model for nodes appearance in cape gooseberry (Physalis peruviana L.) Temperatura base e modelo de simulação da aparição de nós em plantas de fisalis(Physalis peruviana L.)

open access: yesRevista Brasileira de Fruticultura, 2008
Data was analyzed on development of the solanaceen fruit crop Cape gooseberry to evaluate how well a classical thermal time model could describe node appearance in different environments.
Melba Ruth Salazar   +4 more
doaj   +1 more source

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