Results 81 to 90 of about 16,748,922 (299)

Temperatura base para aparecimento de folhas e filocrono da variedade de milho BRS Missões Base temperature for leaf appearance and phyllochron of the BRS Missões maize variety

Ciência Rural, 2009
O objetivo deste trabalho foi estimar a temperatura base para aparecimento de folhas e o filocrono em uma variedade de milho em várias datas de semeadura e dois anos de cultivo. Um experimento de campo foi realizado em Santa Maria, Rio Grande do Sul (RS),
Nereu Augusto Streck, Isabel Lago, Flávia Kaufmann Samboranha, Luana Fernandes Gabriel, Ana Paula Schwantes, Alfredo Schons   +5 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Optimum Sowing Dates for High-Yield Maize when Grown as Sole Crop in the North China Plain

Agronomy, 2019
The maize sole cropping system solves problems related to ground water resource shortages and guarantees food security in the North China Plain. Using optimal sowing dates is an effective management practice for increasing maize yield.
Xuepeng Zhang, Jiali Cheng, Biao Wang, Peng Yan, Hongcui Dai, Yuanquan Chen, Peng Sui   +6 more
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Under the Clouds of War

, 1972
Consists of film clips of World War II events, including Mussolini\u27s invasion of Ethiopia and Hitler\u27s march into Austria.
Time-Life Video
core  

The application of ANFIS prediction models for thermal error compensation on CNC machine tools [PDF]

, 2015
Thermal errors can have significant effects on CNC machine tool accuracy. The errors come from thermal deformations of the machine elements caused by heat sources within the machine structure or from ambient temperature change.
Longstaff, Andrew P., Fletcher, Simon, Abdulshahed, Ali, Abdulshahed, Ali M.   +3 more
core   +1 more source

Desenvolvimento vegetativo e reprodutivo de cultivares de trigo e sua associação com a emissão de folhas Vegetative and reproductive development of wheat cultivars and its association with leaf appearance

Ciência Rural, 2009
O objetivo deste estudo foi determinar a relação da duração das fases vegetativa, reprodutiva e total do ciclo de desenvolvimento com o número final de folhas e com a velocidade de aparecimento de folhas no colmo principal, em cultivares brasileiras de ...
Lidiane Cristine Walter, Nereu Augusto Streck, Hamilton Telles Rosa, Cleber Maus Alberto, Felipe Brendler de Oliveira   +4 more
doaj  

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Desenvolvimento vegetativo de duas cultivares de oliveira na fase de muda Vegetative development of two olive cultivars in seedling phase

Ciência Rural, 2012
O desenvolvimento de plantas, influenciado pela temperatura do ar, pode ser estimado através do conceito de filocrono, definido como o intervalo de tempo entre o surgimento sucessivo de folhas em uma haste, sendo o tempo expresso em °C dia e o filocrono ...
Priscila Maria Martins Lisboa, Fabrina Bolzan Martins, Maria Inês Nogueira Alvarenga, João Vieira Neto, Diogo da Fonseca Reis   +4 more
doaj   +1 more source