Results 61 to 70 of about 991,745 (315)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Application of Double Sigmoid Logistic Models to the Growth of Three Cut Rose Varieties

open access: yesIngeniería e Investigación
The rose is a flower with widespread acceptance worldwide, and Colombia successfully produces rose stems for cutting due to its multiple favorable microclimates.
Javier G. Álvarez-Herrera   +2 more
doaj   +1 more source

Estimativa do filocrono em calêndula Estimating the phyllochron in calendula

open access: yesCiência Rural, 2008
O objetivo deste trabalho foi estimar o filocrono em plantas de calêndula (Calendula officinalis L.) cultivadas em diferentes épocas de semeaduras. Realizaram-se três épocas de semeaduras: 06/04/2005, 23/06/2005 e 03/10/2006, no interior de uma estufa ...
Jana Koefender   +3 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

Development and grain yield of barley genotypes according to sowing date

open access: yesRevista Thema
This study aimed to determine the length of subperiods, development cycle, yield, and grain quality of barley genotypes at different sowing dates. Three experimental lines from a barley breeding program Barley01, Barley02, and Barley03 as well as three ...
Mateus Possebon Bortoluzzi   +4 more
doaj   +1 more source

Development of a thermal sensor for probing small volumes [PDF]

open access: yes, 2012
This thesis presents the design, fabrication and characterisation of a thermal micro-sensor capable of operating on small scale samples. It was initially characterised by measuring the thermal conductivity of 100 μl liquid droplets and thin materials ...
ATHERTON, JOSEPH,JAMES
core  

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

open access: yesFEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Stratospheric thermal damping times [PDF]

open access: yesGeophysical Research Letters, 1997
Radiative damping of stratospheric temperature waves has wide implications for stratospheric physical processes. Damping is linearly parameterized as proportional to the local temperature. Thermal damping is calculated using the Goddard radiative transfer model and 17 years observations.
Paul A. Newman, Joan E. Rosenfield
openaire   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

The Time in Thermal Time

open access: yesJournal for General Philosophy of Science
Accepted for publication in the Journal for General Philosophy of Science, as part of the Special Issue: On Time in the Foundations of Physics (eds. Andrea Oldofredi & Cristian Lopez).
openaire   +3 more sources

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