Results 51 to 60 of about 14,323 (144)

Fucoidan reinforce mitophagy in brown adipose tissue thermogenesis to protect against obesity

Carbohydrate Polymer Technologies and Applications
Background: Obesity is a global health issue, characterized by metabolic dysfunction. Brown adipose tissue (BAT) plays a crucial role in energy expenditure and thermogenesis.
Lizhi Peng, Ruiming Li, Weichang Xie, Ruting Zheng, Yuting Zeng, Jiaqi Liu, Qiaoling Kong, Jicai Lai   +7 more
doaj   +1 more source

A role for brown adipose tissue in diet-induced thermogenesis

, 1997
Measurement of energy balance during voluntary over-eating in rats unequivocally establishes the quantitative importance of diet-induced thermogenesis in energy balance.
Rothwell, Nancy J.
core   +5 more sources

The impact of dietary factors on the function of brown and beige adipose tissues—implications on health and disease

Frontiers in Nutrition
The development of strategies that promote the activation of adaptive thermogenesis in brown and beige adipose tissues is expected to lead to advances in the prevention and treatment of obesity, diabetes, and cardiovascular diseases.
Bruna Bombassaro, Gabriela Batitucci, Marcela Reymond Simoes, Eliana P. Araujo, Eliana P. Araujo, Licio A. Velloso, Licio A. Velloso, Licio A. Velloso   +7 more
doaj   +1 more source

Human RSPO1 Mutation Represses Beige Adipocyte Thermogenesis and Contributes to Diet‐Induced Adiposity

Advanced Science, 2023
Recent genetic evidence has linked WNT downstream mutations to fat distribution. However, the roles of WNTs in human obesity remain unclear. Here, the authors screen all Wnt‐related paracrine factors in 1994 obese cases and 2161 controls using whole ...
Yingkai Sun, Juan Zhang, Jie Hong, Zhongyun Zhang, Peng Lu, Aibo Gao, Mengshan Ni, Zhiyin Zhang, Huanjie Yang, Juan Shen, Jieli Lu, Wenzhi Xue, Qianqian Lv, Yufang Bi, Yi Arial Zeng, Weiqiong Gu, Guang Ning, Weiqing Wang, Ruixin Liu, Jiqiu Wang   +19 more
doaj   +1 more source

A brown fat-enriched adipokine Adissp controls adipose thermogenesis and glucose homeostasis

Nature Communications, 2022
The signaling mechanisms regulating adipose thermogenesis have not been fully elucidated. Here, the authors show that a brown fat-enriched adipokine ADISSP promotes adipose thermogenesis and improves metabolic health independently of b-adrenergic ...
Qingbo Chen, Lei Huang, Dongning Pan, Kai Hu, Rui Li, Randall H. Friedline, Jason K. Kim, Lihua Julie Zhu, David A. Guertin, Yong-Xu Wang   +9 more
doaj   +1 more source

Chemogenetic Excitation of Ventromedial Hypothalamic Steroidogenic Factor 1 (SF1) Neurons Increases Muscle Thermogenesis in Mice

Biomolecules
Allostatic adaptations to a perceived threat are crucial for survival and may tap into mechanisms serving the homeostatic control of energy balance. We previously established that exposure to predator odor (PO) in rats significantly increases skeletal ...
Christina A. Watts, Jordan Smith, Roman Giacomino, Dinah Walter, Guensu Jang, Aalia Malik, Nicholas Harvey, Colleen M. Novak   +7 more
doaj   +1 more source

Cold exposure induces lipid dynamics and thermogenesis in brown adipose tissue of goats

BMC Genomics, 2022
Background Adaptive thermogenesis by brown adipose tissue (BAT) is important to the maintenance of temperature in newborn mammals. Cold exposure activates gene expression and lipid metabolism to provide energy for BAT thermogenesis. However, knowledge of
Xin Liu, Jing Tang, Runan Zhang, Siyuan Zhan, Tao Zhong, Jiazhong Guo, Yan Wang, Jiaxue Cao, Li Li, Hongping Zhang, Linjie Wang   +10 more
doaj   +1 more source

DIETARY OBESITY, EXERCISE TRAINING, AND THERMOGENESIS IN RATS [PDF]

, 1981
The exact contributions of changes in thermogenesis to the energy balance of either rats or humans is not known. There is some evidence that differences in post-prandial heat production (dietary-induced thermogenesis), can explain why some individuals ...
HILL, JAMES OAKLEY
core   +1 more source

Proteostasis in thermogenesis and obesity

Biological Chemistry, 2020
AbstractThe proper production, degradation, folding and activity of proteins, proteostasis, is essential for any cellular function. From single cell organisms to humans, selective pressures have led to the evolution of adaptive programs that ensure proteins are properly produced and disposed of when necessary. Environmental factors such as temperature,
Bartelt, A., Widenmaier, S.B.
openaire   +4 more sources

Targeting Dlat-Trpv3 pathway by hyperforin elicits non-canonical promotion of adipose thermogenesis as an effective anti-obesity strategy

Journal of Advanced Research
Introduction: Promoting adipose thermogenesis is considered as a promising therapeutic intervention in obesity. However, endeavors to develop anti-obesity medications by targeting the canonical thermogenesis regulatory pathway, particularly β3-adrenergic
Sijia Lu, Quanxin Jiang, Peihui Zhou, Limin Yin, Ning Wang, Junting Xu, Qiqi Qian, Mijia Tao, Hanrui Yin, Liu Han, Yunqing Gu, Fei Gao, Junli Liu, Suzhen Chen   +13 more
doaj   +1 more source