Results 1 to 10 of about 1,166,198 (200)

Central vs. Peripheral Action of Thyroid Hormone in Adaptive Thermogenesis: A Burning Topic [PDF]

Cells, 2021
Thyroid hormones (TH) contribute to the control of adaptive thermogenesis, which is associated with both higher energy expenditure and lower body mass index.
Yanis Zekri, Frédéric Flamant, Karine Gauthier   +2 more
doaj   +5 more sources

Adipose Tissue‐Resident Sphingomonas Paucimobilis Suppresses Adaptive Thermogenesis by Reducing 15‐HETE Production and Inhibiting AMPK Pathway [PDF]

Advanced Science
Obesity represents a low‐grade chronic inflammation status, which is associated with compromised adaptive thermogenesis. However, the mechanisms underlying the defective activation of thermogenesis in chronic inflammation remain unclear.
Yucheng Zhu, Ruiqi Yang, Zhangchao Deng, Bohua Deng, Kun Zhao, Chen Dai, Gang Wei, YanJiang Wang, Jinshui Zheng, Zhuqing Ren, Wentao Lv, Yingping Xiao, Zhinan Mei, Tongxing Song   +13 more
doaj   +4 more sources

microRNA-33 maintains adaptive thermogenesis via enhanced sympathetic nerve activity [PDF]

Nature Communications, 2021
Adaptive thermogenesis is regulated by central neuronal circuits. Here, the authors show that microRNA-33 in the brain contributes to the maintenance of brown adipose tissue thermogenesis and whole-body energy balance via enhanced sympathetic nerve tone,
Takahiro Horie, Tetsushi Nakao, Yui Miyasaka, Tomohiro Nishino, Shigenobu Matsumura, Fumiko Nakazeki, Yuya Ide, Masahiro Kimura, Shuhei Tsuji, Randolph Ruiz Rodriguez, Toshimitsu Watanabe, Tomohiro Yamasaki, Sijia Xu, Chiharu Otani, Sawa Miyagawa, Kazuki Matsushita, Naoya Sowa, Aoi Omori, Jin Tanaka, Chika Nishimura, Masataka Nishiga, Yasuhide Kuwabara, Osamu Baba, Shin Watanabe, Hitoo Nishi, Yasuhiro Nakashima, Marina R. Picciotto, Haruhisa Inoue, Dai Watanabe, Kazuhiro Nakamura, Tsutomu Sasaki, Takeshi Kimura, Koh Ono   +32 more
doaj   +3 more sources

Human skeletal muscle mitochondrial uncoupling is associated with cold induced adaptive thermogenesis. [PDF]

PLoS ONE, 2008
BACKGROUND: Mild cold exposure and overfeeding are known to elevate energy expenditure in mammals, including humans. This process is called adaptive thermogenesis.
Sander L J Wijers, Patrick Schrauwen, Wim H M Saris, Wouter D van Marken Lichtenbelt   +3 more
doaj   +4 more sources

Mitochondrial Lipid Signaling and Adaptive Thermogenesis [PDF]

Metabolites, 2021
Thermogenesis is an energy demanding process by which endotherms produce heat to maintain their body temperature in response to cold exposure. Mitochondria in the brown and beige adipocytes play a key role in thermogenesis, as the site for uncoupling ...
Helaina Von Bank, Mae Hurtado-Thiele, Nanami Oshimura, Judith Simcox   +3 more
doaj   +3 more sources

Brown adipocytes local response to thyroid hormone is required for adaptive thermogenesis in adult male mice [PDF]

eLife, 2022
Thyroid hormone (T3) and its nuclear receptors (TR) are important regulators of energy expenditure and adaptive thermogenesis, notably through their action in the brown adipose tissue (BAT).
Yanis Zekri, Romain Guyot, Inés Garteizgogeascoa Suñer, Laurence Canaple, Amandine Gautier Stein, Justine Vily Petit, Denise Aubert, Sabine Richard, Frédéric Flamant, Karine Gauthier   +9 more
doaj   +3 more sources

Emerging roles of histone deacetylases in adaptive thermogenesis [PDF]

Frontiers in Endocrinology, 2023
Brown and beige adipose tissues regulate body energy expenditure through adaptive thermogenesis, which converts energy into heat by oxidative phosphorylation uncoupling.
Ruonan Zhou, Ruonan Zhou, Yue Cao, Yue Cao, Yingying Xiang, Yingying Xiang, Penghua Fang, Wenbin Shang, Wenbin Shang   +8 more
doaj   +2 more sources

The BREAK study protocol: Effects of intermittent energy restriction on adaptive thermogenesis during weight loss and its maintenance. [PDF]

PLoS ONE, 2023
BackgroundAdaptive thermogenesis, defined as the decrease in the energy expenditure components beyond what can be predicted by changes in body mass stores, has been studied as a possible barrier to weight loss and weight maintenance.
Filipa M Cortez, Catarina L Nunes, Luís B Sardinha, Analiza M Silva, Vítor H Teixeira   +4 more
doaj   +2 more sources

Gut bacterial regulation of primate adaptive thermogenesis at high altitude [PDF]

Microbiome
Background Adaptive thermogenesis is a fundamental physiological process by which mammals maintain their body temperature through shivering and non-shivering thermogenesis to adapt to environmental changes. The activation of brown adipose tissue (BAT) is
Xiaochen Wang, Mingyi Zhang, Meng Li, Xiaoming Xu, Yue Sun, Yang Teng, Junping Zhao, Huailiang Xu, Da Zhang, Yueqi Yin, Ying Shen, Jiwei Qi, Zuofu Xiang, Christian Roos, Tingbei Bo, Ming Li   +15 more
doaj   +2 more sources

Loss of histone methyltransferase Smyd3 triggers WAT browning and adaptive thermogenesis via enhancing PPARγ expression in a H4K20me3-dependent manner [PDF]

Journal of Translational Medicine
Adaptive thermogenesis driven by brown/beige adipose tissue has gained attention as a promising strategy for combating obesity. Histone methyltransferase SET and MYND Domain Containing 3 (Smyd3) is strongly associated with metabolic and cardiovascular ...
Meiling Shu, Youzhen Ma, Dandan Zhao, Chen Meng, Lang Chen, Leihao Wang, Jing Liu, Di Yang   +7 more
doaj   +2 more sources