Results 1 to 10 of about 68,391 (212)

Emerging roles of histone deacetylases in adaptive thermogenesis

Frontiers in Endocrinology, 2023
Brown and beige adipose tissues regulate body energy expenditure through adaptive thermogenesis, which converts energy into heat by oxidative phosphorylation uncoupling.
Ruonan Zhou, Ruonan Zhou, Yue Cao, Yue Cao, Yingying Xiang, Yingying Xiang, Penghua Fang, Wenbin Shang, Wenbin Shang   +8 more
doaj   +1 more source

Heat production and volatile biosynthesis are linked via alternative respiration in Magnolia denudata during floral thermogenesis

Frontiers in Plant Science, 2022
Floral thermogenesis is coupled with odor emission in known thermogenic plants. It is widely accepted that elevation in floral temperature can help release of volatile organic compounds (VOCs).
Ruohan Wang, Ruohan Wang, Ling Chen, Ling Chen, Yaping Jia, Yaping Jia, Liya Liu, Liwei Sun, Liwei Sun, Yujun Liu, Yujun Liu, Yun Li, Yun Li   +12 more
doaj   +1 more source

Lipokines and Thermogenesis [PDF]

Endocrinology, 2019
Abstract Adaptive thermogenesis is a catabolic process that consumes energy-storing molecules and expends that energy as heat in response to environmental changes. This process occurs primarily in brown and beige adipose tissue. Thermogenesis is regulated by many factors, including lipid derived paracrine and endocrine hormones called ...
Matthew D Lynes, Sean D Kodani, Yu-Hua Tseng   +2 more
openaire   +2 more sources

Brown adipocyte and browning thermogenesis: metabolic crosstalk beyond mitochondrial limits and physiological impacts

Adipocyte, 2023
Brown adipocytes were proposed to reverse metabolic conditions such as obesity and diabetes, which make them potential for therapeutic applications.
Van Thi-Tuong Nguyen, Vuong Van Vu, Phuc Van Pham   +2 more
doaj   +1 more source

A subpopulation of Bdnf-e1–expressing glutamatergic neurons in the lateral hypothalamus critical for thermogenesis control

Molecular Metabolism, 2020
Objective: Brown adipose tissue (BAT)–mediated thermogenesis plays a key role in energy homeostasis and the maintenance of body temperature. Previous work suggests that brain-derived neurotrophic factor (BDNF) is involved in BAT thermogenesis, but the ...
He You, Pengcheng Chu, Wei Guo, Bai Lu
doaj   +1 more source

Thermogenesis by THADA [PDF]

Developmental Cell, 2017
THADA has been associated with cold adaptation and diabetes in humans, but the cellular and molecular basis of its function has been unknown. Moraru and colleagues (2017) report in this issue of Developmental Cell that it triggers thermogenesis by uncoupling ATP hydrolysis from calcium transport into the endoplasmic reticulum.
Chatterjee, Nirmalya, Perrimon, Norbert
openaire   +3 more sources

Transcriptome Profiles of the Liver in Two Cold-Exposed Sheep Breeds Revealed Different Mechanisms and Candidate Genes for Thermogenesis

Genetics Research, 2021
Cold-induced thermogenesis plays an important role in the survival of lambs exposed to low air temperatures. The liver produces and mediates heat production in mammals; however, to date, little is known about the role of liver genes in cold-induced ...
Dan Jiao, Kaixi Ji, Wenqiang Wang, Hu Liu, Jianwei Zhou, A. Allan Degen, Yunsheng Zhang, Ping Zhou, Guo Yang   +8 more
doaj   +1 more source

AMPK in the Ventromedial Nucleus of the Hypothalamus: A Key Regulator for Thermogenesis

Frontiers in Endocrinology, 2020
Obesity has become a global health issue, but effective therapies remain very limited. Adaptive thermogenesis promotes weight loss by dissipating energy in the form of heat, thereby representing a promising target to counteract obesity.
Hailan Liu, Hailan Liu, Yong Xu, Yong Xu, Fang Hu   +4 more
doaj   +1 more source

Stimulatory, but not anxiogenic, doses of caffeine act centrally to activate interscapular brown adipose tissue thermogenesis in anesthetized male rats

Scientific Reports, 2021
The role of central orexin in the sympathetic control of interscapular brown adipose tissue (iBAT) thermogenesis has been established in rodents. Stimulatory doses of caffeine activate orexin positive neurons in the lateral hypothalamus, a region of the ...
L. Van Schaik, C. Kettle, R. Green, W. Sievers, M. W. Hale, H. R. Irving, D. R. Whelan, J. A. Rathner   +7 more
doaj   +1 more source

mTORC2 sustains thermogenesis via Akt-induced glucose uptake and glycolysis in brown adipose tissue [PDF]

, 2016
Activation of non-shivering thermogenesis (NST) in brown adipose tissue (BAT) has been proposed as an anti-obesity treatment. Moreover, cold-induced glucose uptake could normalize blood glucose levels in insulin-resistant patients.
Albert V, Christoph Handschin, Fatima Bosch, Greco‐Perotto R, Hao Q, Kristoffer Svensson, Marco Colombi, Michael N Hall, Mitsugu Shimobayashi, Sergio Muñoz, Vallerand AL, Verena Albert, Veronica Jimenez   +12 more
core   +4 more sources