Results 41 to 50 of about 4,471,539 (245)

Estudi calorimètric del balanç energètic en l'obesitat genètica i nutricional de la rata [PDF]

open access: yes, 1992
[cat] Aquest treball té com a objectiu principal l'estudi dels mecanismes de control del pes corporal, objectiu que es concreta en l'estudi de les causes bioquímiques i fisiològiques de l'obesitat.
Rafecas Jorba, Immaculada
core   +6 more sources

Adaptive thermogenesis in humans [PDF]

open access: yesInternational Journal of Obesity, 2010
The increasing prevalence of obesity and its comorbidities reflects the interaction of genes that favor the storage of excess energy as fat with an environment that provides ad libitum availability of energy-dense foods and encourages an increasingly sedentary lifestyle.
M, Rosenbaum, R L, Leibel
openaire   +2 more sources

Myeloid p38 activation maintains macrophage–liver crosstalk and BAT thermogenesis through IL‐12–FGF21 axis

open access: yesHepatology, EarlyView., 2022
Physiological activation of myeloid p38 controls macrophage IL‐12 production and crosstalk to the liver by modulating hepatic FGF21, and subsequently, brown adipose tissue thermogenesis during obesity Abstract Obesity features excessive fat accumulation in several body tissues and induces a state of chronic low‐grade inflammation that contributes to ...
María Crespo   +14 more
wiley   +1 more source

Glucocorticoid/Adiponectin Axis Mediates Full Activation of Cold-Induced Beige Fat Thermogenesis

open access: yesBiomolecules, 2021
Glucocorticoids (GCs), a class of corticosteroids produced by the adrenal cortex in response to stress, exert obesity-promoting effects. Although adaptive thermogenesis has been considered an effective approach to counteract obesity, whether GCs play a ...
Liping Luo   +5 more
doaj   +1 more source

RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease

open access: yesHepatology, EarlyView., 2022
RIPK3 dampens mitochondrial bioenergetics and lipid droplet dynamics in metabolic liver disease. Abstract Background and Aims Receptor‐interacting protein kinase 3 (RIPK3) mediates NAFLD progression, but its metabolic function is unclear. Here, we aimed to investigate the role of RIPK3 in modulating mitochondria function, coupled with lipid droplet (LD)
Marta B. Afonso   +16 more
wiley   +1 more source

Weight loss induces changes in adaptive thermogenesis in female and male physique athletes.

open access: yesApplied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme, 2023
Physique athletes lose substantial weight preparing for competitions, potentially altering systemic metabolism. We investigated sex differences in body composition, resting energy expenditure (REE), and appetite-regulating and thyroid hormone changes ...
V. Isola   +5 more
semanticscholar   +1 more source

Cold exposure induces lipid dynamics and thermogenesis in brown adipose tissue of goats

open access: yesBMC Genomics, 2022
Background Adaptive thermogenesis by brown adipose tissue (BAT) is important to the maintenance of temperature in newborn mammals. Cold exposure activates gene expression and lipid metabolism to provide energy for BAT thermogenesis. However, knowledge of
Xin Liu   +10 more
doaj   +1 more source

Exercise-Induced Adaptations to Adipose Tissue Thermogenesis [PDF]

open access: yesFrontiers in Endocrinology, 2020
Exercise training results in beneficial adaptations to numerous tissues and offers protection against metabolic disorders including obesity and type 2 diabetes. Multiple studies have indicated that both white (WAT) and brown (BAT) adipose tissue may play an important role to mediate the beneficial effects of exercise.
Pablo Vidal, Kristin I. Stanford
openaire   +3 more sources

Aging and Immunometabolic Adaptations to Thermogenesis

open access: yesAgeing Research Reviews, 2020
Brown and subcutaneous adipose tissues play a key role in non-shivering thermogenesis both in mice and human, and their activation by adrenergic stimuli promotes energy expenditure, reduces adiposity, and protects against age-related metabolic diseases such as type 2 diabetes (T2D). Low-grade inflammation and insulin resistance characterize T2D.
Lettieri-Barbato, Daniele   +1 more
openaire   +4 more sources

AIDA directly connects sympathetic innervation to adaptive thermogenesis by UCP1

open access: yesNature Cell Biology, 2021
The sympathetic nervous system–catecholamine–uncoupling protein 1 (UCP1) axis plays an essential role in non-shivering adaptive thermogenesis. However, whether there exists a direct effector that physically connects catecholamine signalling to UCP1 in ...
Meng Shi   +20 more
semanticscholar   +1 more source

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