Brown adipocytes local response to thyroid hormone is required for adaptive thermogenesis in adult male mice [PDF]
eLife, 2022 Thyroid hormone (T3) and its nuclear receptors (TR) are important regulators of energy expenditure and adaptive thermogenesis, notably through their action in the brown adipose tissue (BAT).
Yanis Zekri +9 more
doaj +4 more sources
Pharmacological modulation of adaptive thermogenesis: new clues for obesity management? [PDF]
J Endocrinol Invest, 2023 Adaptive thermogenesis represents the main mechanism through which the body generates heat in response to external stimuli, a phenomenon that includes shivering and non-shivering thermogenesis.
V. A. Genchi +12 more
semanticscholar +3 more sources
Human skeletal muscle mitochondrial uncoupling is associated with cold induced adaptive thermogenesis. [PDF]
PLoS ONE, 2008 BACKGROUND: Mild cold exposure and overfeeding are known to elevate energy expenditure in mammals, including humans. This process is called adaptive thermogenesis.
Sander L J Wijers +3 more
doaj +4 more sources
Loss of Brain Angiogenesis Inhibitor-3 (BAI3) G-Protein Coupled Receptor in Mice Regulates Adaptive Thermogenesis by Enhancing Energy Expenditure [PDF]
Metabolites, 2023 Effective energy expenditure is critical for maintaining body weight (BW). However, underlying mechanisms contributing to increased BW remain unknown.
Haifa Alsharif +9 more
doaj +3 more sources
Dietary Iron Deficiency Modulates Adipocyte Iron Homeostasis, Adaptive Thermogenesis, and Obesity in C57BL/6 Mice. [PDF]
J Nutr, 2021 BACKGROUND Adaptive thermogenesis is an iron-demanding pathway, significantly contributing to whole-body energy expenditure. However, the effects of iron-deficient diets on adaptive thermogenesis and obesity remain unknown.
Jin-Seon Yook +7 more
semanticscholar +3 more sources
Huddling behavior regulate adaptive thermogenesis in Brandt’s voles (Lasiopodomys brandtii) [PDF]
Cell & BioscienceBackground Brown adipose tissue (BAT) is the main site of non-shivering thermogenesis (NST) in small mammals, playing an important role in maintaining body temperature and energy balance. Huddling is a behavioral strategy for small rodents to save energy
Min Liu +3 more
doaj +3 more sources
MicroRNA-33 Inhibits Adaptive Thermogenesis and Adipose Tissue Beiging [PDF]
Arteriosclerosis, Thrombosis, and Vascular Biology, 2021 Supplemental Digital Content is available in the text. Objective: Recent studies have identified key transcriptional regulators of brown adipose tissue (BAT) differentiation and function, but posttranscriptional control of this network by microRNAs ...
Martin Schlegel +2 more
exaly +3 more sources
Regulation of Adaptive Thermogenesis and Browning by Prebiotics and Postbiotics [PDF]
Frontiers in Physiology, 2019 Prebiotics are non-digestible food components able to modify host microbiota toward a healthy profile, concomitantly conferring general beneficial health effects.
B. Reynés +3 more
semanticscholar +8 more sources
A Receptor of the Immunoglobulin Superfamily Regulates Adaptive Thermogenesis [PDF]
Cell Reports, 2019 Exquisite regulation of energy homeostasis protects from nutrient deprivation but causes metabolic dysfunction upon nutrient excess. In human and murine adipose tissue, the accumulation of ligands of the receptor for advanced glycation end products (RAGE) accompanies obesity, implicating this receptor in energy metabolism.
Ann Marie Schmidt +2 more
exaly +7 more sources
The paradoxical lean phenotype of hypothyroid mice is marked by increased adaptive thermogenesis in the skeletal muscle [PDF]
Proceedings of the National Academy of Sciences of the United States of America, 2020 Significance The rate of obesity is steadily increasing in the United States and around the world, which is a major health concern, as weight gain is strongly associated with many leading causes of death.
Alejandra Paola Torres Manzo +2 more
exaly +3 more sources