Results 161 to 170 of about 49,624 (286)

Hypothalamus-Peripheral Organ Crosstalk in Energy Metabolism: A Bidirectional Regulatory Network. [PDF]

Endocrinol Metab (Seoul)
Hong Y, Shin S, Cho SK, Kim KW.
europepmc   +1 more source

IMPROVE 2025: The 3rd International Meeting on Pathway‐Related Obesity: Vision & Evidence

Clinical Obesity, Volume 16, Issue 5, October 2026.
ABSTRACT An international cohort of 161 clinicians and researchers from 19 countries attended the 3rd International Meeting on Pathway‐Related Obesity: Vision & Evidence (IMPROVE) in Prague, Czech Republic, on 2–4 July 2025. The aims of the meeting were to advance understanding of hyperphagia and obesity caused by defects in the melanocortin‐4 receptor
Jesús Argente, Erica L. T. van den Akker, Metin Cetiner, Karine Clément, Elizabeth Forsythe, Alastair Garfield, Peter Kühnen, Gabriel Ángel Martos‐Moreno, David Meeker, Hermann L. Müller, Hanneke M. van Santen, Julia von Schnurbein, Bérénice Segrestin, Tomohiro Tanaka, Manuel Tena‐Sempere, Martin Wabitsch, Stefanie Zorn, I. Sadaf Farooqi   +17 more
wiley   +1 more source

Housing at 27 °C, a Near-Thermoneutral Temperature, Exacerbates Metabolic Dysfunction-Associated Steatohepatitis in C57BL/6J Mice. [PDF]

Int J Mol Sci
Hao L, Khan MSH, Zu Y, Wang S.
europepmc   +1 more source

METTL18 is Required for Developmental, Metabolic, and Endocrine Regulation of Mammalian Growth

The FASEB Journal, Volume 40, Issue 17, 15 September 2026.
METTL18 is essential for histidine Nτ‐methylation of proteins, normal embryonic development, iron and lipid metabolism, and hormone signaling pathways that support postnatal growth in mice. The main points of this study are as follows: First, mouse METTL18 catalyzes histidine Nτ‐methylation. Next, Mettl18 KO embryos are significantly smaller than their
Fumiya Kasai, Jun‐Dal Kim, Koichiro Kako, Naoto Muromachi, Takeru Saito, Yao Yuan, Hayase Mizukami, Nana Kishikawa, Kanako Nakamura, Kaori Motomura, Hiroaki Daitoku, Yuuki Imai, Sho Sekiguchi, Kazuhiko Horiguchi, Satoshi Narumi, Masanobu Yamada, Akiyoshi Fukamizu   +16 more
wiley   +1 more source

EID1 overexpression in brown adipose tissue enhances cold-induced thermogenesis in male mice. [PDF]

iScience
Takahashi I, Vargas D, Watanabe Y, Sato T, Miyazaki M, Hanaoka H, Nakajima T, Kaneko R, Amano I, Nakanishi T, Lizcano F, Koibuchi N, Shimokawa N.   +12 more
europepmc   +1 more source

Inositol pyrophosphate kinases in health and disease

FEBS Letters, Volume 600, Issue 17, Page 2379-2396, September 2026.
In mammalian cells, IP6Ks and PPIP5Ks are the key kinases synthesizing the inositol pyrophosphates 5PP‐InsP5 and InsP8. They are essential for early development but also mediate age‐related diseases, including metabolic disorders, cardiovascular diseases, neurodegenerative diseases, and cancers.
Changchang Xing, Chao Wang, Yuanyuan Chen, Weiwei Cheng, Zhaolei Jiang, Alex F. Chen, Chenglai Fu   +6 more
wiley   +1 more source

Understanding adipocyte heterogeneity across species, depot, and disease. [PDF]

Biochem Soc Trans
Kitto ES, Kult Perry S, Emont MP.
europepmc   +1 more source

Agnuside Stabilizes the Complex I Assembly Factor NDUFAF6 to Reinforce Mitochondrial Efficiency and Thermogenic Responsiveness

Advanced Science, Volume 13, Issue 50, 7 September 2026.
ABSTRACT Brown and beige adipocytes dissipate energy as heat, yet effective strategies to enhance their mitochondrial efficiency remain limited. Here, we identify Agnuside (AGN) as a selective stabilizer of the complex I assembly factor NDUFAF6. AGN directly binds cytosolic NDUFAF6, suppresses its ubiquitination, prolongs its half‐life, and facilitates
Qingwen Zhao, Li Xie, Qianzhuo Wang, Shuying Dai, Bei Li, Yingjuan Zhang, Zhe Sun, Yue Gao   +7 more
wiley   +1 more source

Duration-dependent gut microbiota disruption drives opposing effects on adipose thermogenesis in obese mice. [PDF]

Front Microbiol
Feng T, Cui Y, Bi X, Liu Y, Yang L, Ouyang D, Xu W, Zhao Y, Xi Y, Yang Q, Sun Y, Wang X, Li M.   +12 more
europepmc   +1 more source

Running Distance Is Associated With Components of Total Energy Expenditure in Amenorrhoeic and Non-Amenorrhoeic Endurance Runners. [PDF]

Scand J Med Sci Sports
ABSTRACT Some competitive runners strategically regulate their body weight to optimize race performance by balancing energy intake and expenditure. The constrained total energy expenditure (TEE) model suggests that exercise energy expenditure (EEE) is sustained through compensatory reductions in other components of TEE, including resting metabolic rate
Uchizawa A, Kondo E, Enomoto Y, Yajima K, Tamai S, Watanabe K, Ito A, Kosugi M, Higaki Y, Sagayama H.   +9 more
europepmc   +2 more sources