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Ash2l deficiency impairs adipose tissue thermogenesis and exacerbates obesity in mice. [PDF]

open access: yesCell Mol Biol Lett
Hu Y   +11 more
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Nonshivering thermogenesis

Brain Research Bulletin, 1984
Nonshivering thermogenesis was originally defined as a cold-induced increase in heat production not associated with the muscle activity of shivering. Recent research shows it to be a metabolic process located primarily in brown adipose tissue and controlled by the activity of the sympathetic nervous supply of this tissue.
Jean Himms-Hagen, J Himms-Hagen
exaly   +3 more sources

Thermogenesis and Obesity

British Medical Bulletin, 1981
Obesity is generally considered to be the major nutritional disorder in the Western world, affecting, for example, some 10% of the middle-aged population in the UK, with up to 50% of the same group being overweight and at an increased risk of disease and early death.
W P, James, P, Trayhurn
openaire   +2 more sources

Perinatal thermogenesis

Early Human Development, 1995
The rapid initiation of thermogenesis is crucial for the survival of newborn infants. At birth the fetus must adapt to cooling, increased oxygenation and separation from the placenta. An experimental approach in the chronically instrumental fetal sheep of 'simulated birth in utero' allowed the evaluation of each of these stimuli sequentially.
T R, Gunn, P D, Gluckman
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Igniting adipocyte thermogenesis

Cell, 2022
Maintenance of body temperature is intimately tied to energy expenditure and body weight regulation. In this issue of Cell, Li, Wang, et al. discovered that localized hyperthermia induces the thermogenic program to increase energy expenditure and decrease body weight in mice and humans.
Raghav, Jain, Judith, Simcox
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Thermogenesis in Muscle

Annual Review of Physiology, 1994
Skeletal muscles are most often examined at the cellular level in relationship to their primary role in force generation. Throughout the animal kingdom, regardless of phylogeny, muscle generates heat. Exercise, shivering, and nonshivering thermogenesis provide excess heat in muscle that affords adaptive significance to a wide variety of organisms ...
openaire   +2 more sources

Cellular Thermogenesis

Annual Review of Physiology, 1976
The principal conclusion presented in this review is that no single mechanism underlies any of the examples of basal or altered cellular thermogenesis. Both increased Na+ pump operation and uncoupling may occur to a greater or lesser extent, as may other heat-producing mechanisms.
openaire   +2 more sources

FEVER AND BIOCHEMICAL THERMOGENESIS

Pediatrics, 1971
Serum free fatty acid versus glycerol ratios were decreased in human newborn infants during pyrexia or cold injury, but remained practically unchanged in older infants and children. Decreased ratios in the newborn resulted exclusively from an increase in serum glycerol.
N, Matsaniotis   +3 more
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Thermogenesis in decomposing carcasses

Forensic Science International, 2013
It is of fundamental importance in forensic entomology that the factors controlling carcass temperatures during decomposition are thoroughly understood. The thermal environment to which fly larvae are exposed is the primary influence on their growth rate, and hence affects any estimate of minimum time since death using such specimens in homicide ...
Johnson, Aidan P   +2 more
openaire   +3 more sources

Leptin and thermogenesis in humans

Acta Physiologica Scandinavica, 1997
We examined changes in serum leptin concentrations and thermogenesis in 12 healthy men (39 ± 2 years, BMI 22.8 ± 0.3 kg m−2) during a 4 h euglycaemic hyperinsulinaemia performed on a control day and after a day of a competitive marathon run. As compared with the control day, after the marathon, baseline FFA concentration (543 ± 0.73 vs. 955 ± 96 μmol L−
J A, Tuominen   +4 more
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