Results 61 to 70 of about 49,768 (263)

Supporting Information - Supplemental Experimental Procedure : Muscle nonshivering thermogenesis in a feral mammal

, 2019
Muscle nonshivering thermogenesis (NST) was recently suggested to play an important role in thermoregulation of species lacking brown adipose tissue (BAT). The mechanism, which is independent of muscle contractions, produces heat based on the activity of
Walter Arnold, Gabrielle Stalder, Perica Jurcevic, Julia Nowack, Minh Hien Le, Johanna Painer, Maria Kral, Steve Smith, Claudia Bieber, Thomas Ruf, Sebastian G. Vetter   +10 more
core   +1 more source

Water-Induced Thermogenesis [PDF]

The Journal of Clinical Endocrinology & Metabolism, 2003
Drinking lots of water is commonly espoused in weight loss regimens and is regarded as healthy; however, few systematic studies address this notion. In 14 healthy, normal-weight subjects (seven men and seven women), we assessed the effect of drinking 500 ml of water on energy expenditure and substrate oxidation rates by using whole-room indirect ...
Michael, Boschmann, Jochen, Steiniger, Uta, Hille, Jens, Tank, Frauke, Adams, Arya M, Sharma, Susanne, Klaus, Friedrich C, Luft, Jens, Jordan   +8 more
openaire   +2 more sources

Temperature homeostasis disruption and hypothalamic alterations in experimental drug‐resistant epilepsy

Epilepsia, EarlyView.
Abstract Objective Elevated body temperature may increase seizure risk, yet the relationship between thermoregulation and seizures, as well as the underlying mechanisms, remains poorly understood. We investigated whether thermoregulatory control is altered in experimental temporal lobe epilepsy (TLE), as such impairment could reduce the ability of ...
Rossella Di Sapia, Akash Bera, Omar Mamad, James D. Mills, Benjamin Villasana‐Salazar, Giada Lavigna, Edoardo Micotti, Manuela Conticello, Asmin Alam, Roberto Chiesa, Francesca Pagani, Roberta Frapolli, Angelo M. Lavecchia, Christodoulos Xinaris, Eleonora Aronica, Andre Altmann, Teresa Ravizza, Sanjay M. Sisodiya, David C. Henshall, Annamaria Vezzani   +19 more
wiley   +1 more source

Syncing Health Timing: Exploring the Interplay of Circadian Rhythms, Obesity, and Cardiovascular Diseases

Food Safety and Health, EarlyView.
Circadian rhythm disruption impairs metabolic regulation, appetite control, and vascular function, promoting obesity and cardiovascular diseases. Evidence highlights a bidirectional relationship where metabolic disorders further disturb circadian timing.
Ghizal Fatima, István Dalmadi, Anna Jánosi, Krisztina Takács, Eszter Halmy   +4 more
wiley   +1 more source

Fucoidan reinforce mitophagy in brown adipose tissue thermogenesis to protect against obesity

Carbohydrate Polymer Technologies and Applications
Background: Obesity is a global health issue, characterized by metabolic dysfunction. Brown adipose tissue (BAT) plays a crucial role in energy expenditure and thermogenesis.
Lizhi Peng, Ruiming Li, Weichang Xie, Ruting Zheng, Yuting Zeng, Jiaqi Liu, Qiaoling Kong, Jicai Lai   +7 more
doaj   +1 more source

Human RSPO1 Mutation Represses Beige Adipocyte Thermogenesis and Contributes to Diet‐Induced Adiposity

Advanced Science, 2023
Recent genetic evidence has linked WNT downstream mutations to fat distribution. However, the roles of WNTs in human obesity remain unclear. Here, the authors screen all Wnt‐related paracrine factors in 1994 obese cases and 2161 controls using whole ...
Yingkai Sun, Juan Zhang, Jie Hong, Zhongyun Zhang, Peng Lu, Aibo Gao, Mengshan Ni, Zhiyin Zhang, Huanjie Yang, Juan Shen, Jieli Lu, Wenzhi Xue, Qianqian Lv, Yufang Bi, Yi Arial Zeng, Weiqiong Gu, Guang Ning, Weiqing Wang, Ruixin Liu, Jiqiu Wang   +19 more
doaj   +1 more source

The impact of dietary factors on the function of brown and beige adipose tissues—implications on health and disease

Frontiers in Nutrition
The development of strategies that promote the activation of adaptive thermogenesis in brown and beige adipose tissues is expected to lead to advances in the prevention and treatment of obesity, diabetes, and cardiovascular diseases.
Bruna Bombassaro, Gabriela Batitucci, Marcela Reymond Simoes, Eliana P. Araujo, Eliana P. Araujo, Licio A. Velloso, Licio A. Velloso, Licio A. Velloso   +7 more
doaj   +1 more source

Nested Selves: Self‐Organization and Shared Markov Blankets in Prenatal Development in Humans

Topics in Cognitive Science, EarlyView., 2023
Abstract The immune system is a central component of organismic function in humans. This paper addresses self‐organization of biological systems in relation to—and nested within—other biological systems in pregnancy. Pregnancy constitutes a fundamental state for human embodiment and a key step in the evolution and conservation of our species. While not
Anna Ciaunica, Michael Levin, Fernando E. Rosas, Karl Friston   +3 more
wiley   +1 more source

A brown fat-enriched adipokine Adissp controls adipose thermogenesis and glucose homeostasis

Nature Communications, 2022
The signaling mechanisms regulating adipose thermogenesis have not been fully elucidated. Here, the authors show that a brown fat-enriched adipokine ADISSP promotes adipose thermogenesis and improves metabolic health independently of b-adrenergic ...
Qingbo Chen, Lei Huang, Dongning Pan, Kai Hu, Rui Li, Randall H. Friedline, Jason K. Kim, Lihua Julie Zhu, David A. Guertin, Yong-Xu Wang   +9 more
doaj   +1 more source

Adss1–HDAC3 Interaction: A Novel Mechanism for Epigenetic Regulation of Metabolism in Adipose Tissue

iNew Medicine, EarlyView.
ABSTRACT Obesity and its related metabolic disorders have emerged as global public health challenges with underlying mechanisms involving an imbalance between energy storage and expenditure in the adipose tissue. In recent years, with the deepening research on adipose tissue metabolism, the cross talk between metabolic enzymes and epigenetic regulation
Jiarui Zhao, Jingjing Sun, Yan Lu, Ying Yang   +3 more
wiley   +1 more source