EID1 overexpression in brown adipose tissue enhances cold-induced thermogenesis in male mice. [PDF]
Takahashi I +12 more
europepmc +1 more source
ATP Release and Purinergic Signaling Potentiate β‐Adrenergic Effects on Brown Adipocytes
ABSTRACT Aim Brown adipose tissue (BAT) specializes in energy consumption and thermogenesis in response to cold stress. Brown adipocytes (BA) express purinergic receptors, yet little is known about the source of extracellular ATP and the role of purinergic signaling, and the potential interaction with β‐adrenergic signaling.
Marco Tozzi +8 more
wiley +1 more source
Housing at 27 °C, a Near-Thermoneutral Temperature, Exacerbates Metabolic Dysfunction-Associated Steatohepatitis in C57BL/6J Mice. [PDF]
Hao L, Khan MSH, Zu Y, Wang S.
europepmc +1 more source
IMPROVE 2025: The 3rd International Meeting on Pathway‐Related Obesity: Vision & Evidence
ABSTRACT An international cohort of 161 clinicians and researchers from 19 countries attended the 3rd International Meeting on Pathway‐Related Obesity: Vision & Evidence (IMPROVE) in Prague, Czech Republic, on 2–4 July 2025. The aims of the meeting were to advance understanding of hyperphagia and obesity caused by defects in the melanocortin‐4 receptor
Jesús Argente +17 more
wiley +1 more source
Beyond Pleasure: Unraveling the Multifaceted Role of Dopamine in Obesity and Metabolic Regulation. [PDF]
Yang S +9 more
europepmc +1 more source
Mitochondrial uncoupling and thermogenesis [PDF]
openaire +1 more source
Life‐stage variation in Sable Shearwater (Ardenna carneipes) physiology assessed using proteomics
Life‐stage transitions in seabirds involve substantial shifts in physiological demands, yet the molecular mechanisms underpinning these changes remain poorly resolved. Here we applied untargeted data‐independent acquisition mass spectrometry (DIA‐MS) to characterize and compare the plasma proteomes of fledgling and adult Sable Shearwaters Ardenna ...
Alix M. de Jersey +5 more
wiley +1 more source
Duration-dependent gut microbiota disruption drives opposing effects on adipose thermogenesis in obese mice. [PDF]
Feng T +12 more
europepmc +1 more source
Abstract During pregnancy, thermoregulation is tightly controlled to protect the foetus from harmful elevated temperatures. Stress‐induced hyperthermia is a component of the stress response that increases alertness to a perceived threat. Previous literature has shown that like other aspects of the stress response, stress‐induced hyperthermia is ...
Andrew M. Stewart +2 more
wiley +1 more source
Exercise and cold exposure as dual physiological stressors in MASLD: AMPK-mediated metabolic adaptation and interorgan crosstalk. [PDF]
Wang S, Gao Y, Wang Y, Wang J, Liu Y.
europepmc +1 more source

