Results 51 to 60 of about 49,624 (286)

Nardilysin in adipocytes regulates UCP1 expression and body temperature homeostasis

open access: yesScientific Reports, 2022
Brown adipose tissue (BAT) dissipates chemical energy as heat through uncoupling protein 1 (UCP1). The induction of mitochondrial reactive oxygen species (ROS) in BAT was recently identified as a mechanism that supports UCP1-dependent thermogenesis.
Sayaka Saijo   +8 more
doaj   +1 more source

Hypertension in obesity: A focus on individualized pharmacotherapy and the role of body composition, on behalf of the European Society of Hypertension Working Group on Diabetes and Metabolic Risk Factors and Working Group on Lifestyle, Cardiovascular Pharmacotherapy and Adherence

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Hypertension in obesity represents a major global health challenge, closely linked to the global epidemics of obesity, type 2 diabetes and metabolic dysfunction. Excess adiposity contributes to elevated blood pressure through multiple, interrelated mechanisms, including activation of the renin–angiotensin–aldosterone system, sympathetic nervous system ...
Christina Antza   +12 more
wiley   +1 more source

Effects of Physical Training on Enhanced Nonshivering Thermogenesis in Cold Acclimated Rats [PDF]

open access: yes, 1989
This study suggested that the effects of physical endurance training on nonshivering thermogenesis to acute cold exposure in male rats acclimated at cold environmental temperatureArticle環境科学年報11:79-84(1989)research ...
上田, 五雨   +2 more
core  

Real‐time biosensing of Parkinson's disease biomarkers via NIR‐activated upconversion nanoparticles

open access: yesBMEMat, EarlyView.
Schematic illustration of the luminescence resonance energy transfer‐driven core‐shell‐shell UCNPs (cssUCNPs@Fluo4) nanoprobe for simultaneous monitoring of Ca²⁺‐temperature dynamics in Parkinson's disease models. Abstract Parkinson's disease (PD) is a progressive neurodegenerative disorder with incompletely understood pathophysiology, necessitating ...
Jialin Liu   +9 more
wiley   +1 more source

The Raphe Pallidus and the Hypothalamic-Pituitary-Thyroid Axis Gate Seasonal Changes in Thermoregulation in the Hibernating Arctic Ground Squirrel (Urocitellus parryii)

open access: yesFrontiers in Physiology, 2018
Thermoregulation is necessary to maintain energy homeostasis. The novel discovery of brown adipose tissue (BAT) in humans has increased research interests in better understanding BAT thermogenesis to restore energy balance in metabolic disorders.
Carla Frare   +6 more
doaj   +1 more source

Latest advances in the regulatory genes of adipocyte thermogenesis

open access: yesFrontiers in Endocrinology, 2023
An energy imbalance cause obesity: more energy intake or less energy expenditure, or both. Obesity could be the origin of many metabolic disorders, such as type 2 diabetes and cardiovascular disease.
Tao Nie   +3 more
doaj   +1 more source

The Liver as a Hub in Thermogenesis [PDF]

open access: yesCell Metabolism, 2017
Manipulating thermogenesis could increase energy expenditure and improve metabolism. Brown fat is a major site of nonshivering thermogenesis, but other tissues, notably muscle and liver, can contribute to cold adaptation. In this issue, Simcox et al.
openaire   +2 more sources

Temperature homeostasis disruption and hypothalamic alterations in experimental drug‐resistant epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective Elevated body temperature may increase seizure risk, yet the relationship between thermoregulation and seizures, as well as the underlying mechanisms, remains poorly understood. We investigated whether thermoregulatory control is altered in experimental temporal lobe epilepsy (TLE), as such impairment could reduce the ability of ...
Rossella Di Sapia   +19 more
wiley   +1 more source

Supporting Information - Supplemental Experimental Procedure : Muscle nonshivering thermogenesis in a feral mammal

open access: yes, 2019
Muscle nonshivering thermogenesis (NST) was recently suggested to play an important role in thermoregulation of species lacking brown adipose tissue (BAT). The mechanism, which is independent of muscle contractions, produces heat based on the activity of
Walter Arnold   +10 more
core   +1 more source

Water-Induced Thermogenesis [PDF]

open access: yesThe Journal of Clinical Endocrinology & Metabolism, 2003
Drinking lots of water is commonly espoused in weight loss regimens and is regarded as healthy; however, few systematic studies address this notion. In 14 healthy, normal-weight subjects (seven men and seven women), we assessed the effect of drinking 500 ml of water on energy expenditure and substrate oxidation rates by using whole-room indirect ...
Michael, Boschmann   +8 more
openaire   +2 more sources

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