Results 191 to 200 of about 49,624 (286)

Decadal Bowhead Whale Baleen Stable Isotope and Hormone Chronologies (1985–2010) Provide Insight Into Arctic Ecosystem Change

Global Change Biology Communications, Volume 1, Issue 3, September 2026.
Long‐term chronologies constructed from individual bowhead baleen plates reveal stable isotope declines consistent with regional Arctic food web or productivity changes superimposed on global anthropogenic C and N inputs, while relatively stable hormone concentrations over the same period provide no evidence of a concomitant increase in physiological ...
Cory J. D. Matthews, Justine M. Hudson, Nadine S. J. Lysiak, Kathleen E. Hunt, Mads Peter Heide‐Jørgensen, Steven H. Ferguson   +5 more
wiley   +1 more source

Sphingosine kinase 2 regulates adipocyte browning and whole-body metabolism. [PDF]

Sci Adv
Brown RDR, Weigel C, Vijayan Y, Tyc KM, Carter C, Green CD, Spiegel S.   +6 more
europepmc   +1 more source

Bile acid metabolism and signaling in human and animal health: A One Health perspective

iMetaOmics, Volume 3, Issue 3, September 2026.
Bile acids maintain host homeostasis through enterohepatic circulation, microbial transformation, and bile acid receptor signaling, thereby regulating glucose and lipid metabolism, intestinal barrier integrity, and immunity. These effects support human disease intervention and health‐oriented animal production, reducing drug dependence and residue ...
Lei Li, Shuai Liu, Zhijun Cao, Yangchun Cao, Shengru Wu, Lu Deng, Junhu Yao, Jun Zhang   +7 more
wiley   +1 more source

Insulin Resistance: An Update on Biochemical and Pathophysiological Mechanisms and Impact on Various Diseases

iNew Medicine, Volume 2, Issue 3, September 2026.
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little, Stefan Offermanns, Haaglim Cho, Zhiping Liu, Pinglian Yang, Qiaozhu Su, Henry Wade, Wah Yang, Danielle Kamato, Neale Cohen, Alex Bobik, Iqra Ilyas, Suowen Xu   +12 more
wiley   +1 more source

Transcriptome analysis of brown adipose tissue in Brandt's vole treated with tannic acid under cold exposure. [PDF]

BMC Genomics
Shen QY, Chen KX, Ma XW, Yang SM, Wei WH, Yang FP, Dai X.   +6 more
europepmc   +1 more source

UCP1-Dependent Thermogenic Adipose Tissue in Human Disease: Adipose-Centered Mechanisms, Biomarker Limitations, and Translational Perspectives. [PDF]

Int J Mol Sci
Yan M, Wang H, Sha W, Fu Y.
europepmc   +1 more source

Mitochondrial CLPP in Health and Disease: Mechanisms, Therapeutic Duality and Emerging Opportunities

Journal of Inherited Metabolic Disease, Volume 49, Issue 5, September 2026.
The graphical abstract illustrates the context‐dependent therapeutic modulation of CLPP. Pharmacological CLPP activation has reached clinical application in cancer (black arrow), whereas reduced CLPP activity has shown beneficial effects experimentally in models of primary mitochondrial disease and metabolic syndrome, as well as cancer (grey arrows ...
Lea Isermann, Aleksandra Trifunovic
wiley   +1 more source

TRPA1 deficiency alters brown adipose tissue proteome and thermogenic gene expression during cold exposure in mice. [PDF]

Biochem Biophys Rep
Sua-Cespedes CD, Lima OG, Vasconcelos LM, Zanetti G, Avelino da Silva M, Moraes MN, Gomes G, Festuccia WT, Castrucci AML, Lacerda JT.   +9 more
europepmc   +1 more source

Inter‐tissue relationships of gene expression in liver, muscle and adipose tissue of children with end‐stage chronic liver disease

Journal of Pediatric Gastroenterology and Nutrition, Volume 83, Issue 3, Page 500-508, September 2026.
Abstract Objectives End‐stage chronic liver disease in children is associated with sarcopenia and aberrant adipose tissue mass. We investigated correlations between liver pathology‐associated gene pathways (fibrosis, inflammation and steatosis) and metabolic genes in muscle and adipose tissue.
Eirini Kyrana, Cheng Zhang, Han Jin, Siamak Salehi, Jonathan C. K. Wells, Maesha Deheragoda, Ragai R. Mitry, Anil Dhawan   +7 more
wiley   +1 more source

Rewiring Adipocyte Plasticity: The Redox-Mitochondrial Axis as a Driver of Beige Fat Immunometabolism and Adipose Inflammation. [PDF]

Biomolecules
Aissa-Brahim F, Yang S, Zhou X, Li Z, Bu S.   +4 more
europepmc   +1 more source