Results 171 to 180 of about 45,421 (286)

Mitochondrial physiology in cardiac muscle of deer mice native to high altitude

The Journal of Physiology, EarlyView.
Abstract figure legend High‐altitude deer mice exhibited evolved changes in mitochondrial energy metabolism and reactive oxygen species (ROS) management that may support cardiac performance under cold hypoxic conditions. High‐altitude mice had increased activity of lactate dehydrogenase (LDH) in the heart, probably enhancing the capacity for lactate ...
Ranim Saleem, Samuel G. Robichaud, Simon G. Lamarre, Graham R. Scott   +3 more
wiley   +1 more source

Rewiring Adipocyte Plasticity: The Redox-Mitochondrial Axis as a Driver of Beige Fat Immunometabolism and Adipose Inflammation. [PDF]

Biomolecules
Aissa-Brahim F, Yang S, Zhou X, Li Z, Bu S.   +4 more
europepmc   +1 more source

The influence of haemoglobin–O2 affinity on aerobic capacity in hypoxia in high‐altitude deer mice (Peromyscus maniculatus)

The Journal of Physiology, EarlyView.
Abstract figure legend The influence of haemoglobin–O2 affinity on aerobic capacity in hypoxia has been contentious. Many high‐altitude natives have greater haemoglobin–O2 affinity (lower P50, the O2 pressure at 50% haemoglobin saturation) than their low‐altitude counterparts, but the advantages of this change for aerobic metabolism have often remained
Kayla M. Garvey, Graham R. Scott
wiley   +1 more source

Projection-defined hypothalamic outputs differentially regulate thermogenesis and lipolysis. [PDF]

Proc Natl Acad Sci U S A
Min H, Zheng Q, Yang Y.
europepmc   +1 more source

Δ9 Tetrahydrocannabinol and cannabis extracts differentially improve adipoinsular dysfunction in diet‐induced obesity

The Journal of Physiology, EarlyView.
Abstract figure legend THC and extract administered to diet‐induced obese mice reduced body weight and fat storage. Extract, but not THC, improved glucose clearance by a mechanism that may include restoring adipoinsular function. Abstract Diet‐induced obesity (DIO) is associated with dysregulated adipoinsular axis and endocannabinoid system (eCBS ...
Bryant Avalos, Martin Olmos, Courtney P. Wood, Camila Alvarez, Haley M. Read, Parima Udompholkul, Theodore Garland Jr, Nicholas V. DiPatrizio   +7 more
wiley   +1 more source

Attenuation of Adaptive Thermogenesis by a Culinary Dose of Red Pepper During 24-Hour Negative Energy Balance. [PDF]

Nutr Rev
Ludy MJ, Moore GE, Mattes RD, Westerterp-Plantenga MS.   +3 more
europepmc   +1 more source

Age‐ and sex‐specific modulation of human cardiac electrophysiology by doxorubicin

The Journal of Physiology, EarlyView.
Abstract figure legend DOX differentially impacts cardiac electrophysiology based on sex and age. Sex differences were primarily observed among younger hearts, where action potential duration (APD) prolongation was observed in females, but not in males. Created using BioRender. George, S. (2026) https://BioRender.com/wresf1k Abstract Acute doxorubicin (
Sharon A. George, Amber V. Mills, Erin O'Neill, Sofian N. Obaid, Igor R. Efimov, Tatiana Efimova   +5 more
wiley   +1 more source

Increased Brown Adipose Tissue Thermogenesis in Phenylketonuria. [PDF]

MedComm (2020)
López-Rey N, Cabaleiro A, Pata MP, Peyrou M, Estévez-Salguero Á, Fernández-Sanmartín P, Morgan DA, Ferreira V, Sánchez-Pintos P, Folgueira C, Diéguez C, Urisarri A, González-García I, Seoane LM, Rahmouni K, Villarroya F, Couce ML, Nogueiras R, López M.   +18 more
europepmc   +1 more source

Association of Physical Activity With All‐Cause and CVD Mortality Across Metabolic and Obesity Phenotypes

Diabetes, Obesity and Metabolism, Volume 28, Issue 8, Page 7006-7017, August 2026.
ABSTRACT Aims To examine the independent and joint associations of metabolic status, obesity, and physical activity with all‐cause and cardiovascular disease (CVD) mortality across metabolic–obesity phenotypes. Materials and Methods We analysed 442 666 adults from the Korean National Health Insurance Service health screening cohort (2009–2012 ...
Yunmin Han, Younghwan Choi, Soomin Lee, Yeon Soo Kim   +3 more
wiley   +1 more source

Temperature as a Metabolic Signal Linking Neural and Endocrine Circuits to Energy Homeostasis. [PDF]

Int J Mol Sci
Mo X, Kim YB, Huang C, Fan S.
europepmc   +1 more source