Results 191 to 200 of about 83,845 (311)

Potential health benefits of cold‐water immersion: the central role of PGC‐1α

The Journal of Physiology, EarlyView.
Abstract figure legend Cold‐water immersion (CWI) elicits autonomic, somato‐motoric (shivering thermogenesis), endocrine and metabolic, sensory transduction, and local biophysical effects that may converge on the transcriptional co‐activator PGC‐1α (centre).
Erich Hohenauer, Wafa Douzi, Johannes Burtscher   +2 more
wiley   +1 more source

Dual Role of Transcription Factors in the Development and Thermogenic Function of Brown Adipose Tissue. [PDF]

Int J Med Sci
Wang S, Xie F, Li W, Xie W, Cheng H.
europepmc   +1 more source

Abcc1 deficiency protects from corticosterone but not cortisol‐induced adiposity and insulin resistance in a sex‐specific manner

The Journal of Physiology, EarlyView.
Abstract figure legend A mouse model of exogenous glucocorticoid (GC) treatment was used to determine (1) if corticosterone induced the same metabolic dysregulation as cortisol, and (2) whether these differences were mediated by the corticosterone‐specific transmembrane exporter Abcc1.
Mhairi A. Paul, Boglarka Nagy, Sofia Laforest, Joanna P. Simpson, William Mungall, Natalie Z. M. Homer, Robert K. Semple, Ruth Andrew, Roland H. Stimson, Mark Nixon   +9 more
wiley   +1 more source

Accumulation of succinate controls activation of adipose tissue thermogenesis

Nature, 2018
E. Mills, K. Pierce, Mark P. Jedrychowski, Ryan Garrity, Sally Winther, S. Vidoni, T. Yoneshiro, J. Spinelli, Gina Z. Lu, L. Kazak, Alexander S. Banks, M. Haigis, S. Kajimura, M. Murphy, S. Gygi, C. Clish, Edward T. Chouchani   +16 more
semanticscholar   +1 more source

Mitochondrial physiology in cardiac muscle of deer mice native to high altitude

The Journal of Physiology, EarlyView.
Abstract figure legend High‐altitude deer mice exhibited evolved changes in mitochondrial energy metabolism and reactive oxygen species (ROS) management that may support cardiac performance under cold hypoxic conditions. High‐altitude mice had increased activity of lactate dehydrogenase (LDH) in the heart, probably enhancing the capacity for lactate ...
Ranim Saleem, Samuel G. Robichaud, Simon G. Lamarre, Graham R. Scott   +3 more
wiley   +1 more source

Intermittent Fasting: A Metabolically Focused Therapeutic Strategy for Obesity. [PDF]

Nutrients
Diaz-Garrido N, Zagmutt S, Regaldiz A, Cisternas P, Bastías-Pérez M.   +4 more
europepmc   +1 more source

Glycogen metabolism links glucose homeostasis to thermogenesis in adipocytes

Nature, 2021
O. Keinan, Joseph M. Valentine, Haopeng Xiao, S. Mahata, Shannon M. Reilly, Mohammad Abu-Odeh, Julia H. DeLuca, Benyamin Dadpey, Leslie Cho, A. Pan, R. Yu, Yang Dai, C. Liddle, M. Downes, R. Evans, A. Lusis, M. Laakso, Edward T. Chouchani, M. Rydén, A. Saltiel   +19 more
semanticscholar   +1 more source

Age‐ and sex‐specific modulation of human cardiac electrophysiology by doxorubicin

The Journal of Physiology, EarlyView.
Abstract figure legend DOX differentially impacts cardiac electrophysiology based on sex and age. Sex differences were primarily observed among younger hearts, where action potential duration (APD) prolongation was observed in females, but not in males. Created using BioRender. George, S. (2026) https://BioRender.com/wresf1k Abstract Acute doxorubicin (
Sharon A. George, Amber V. Mills, Erin O'Neill, Sofian N. Obaid, Igor R. Efimov, Tatiana Efimova   +5 more
wiley   +1 more source

The histone methyltransferase SUV420H2 regulates brown and beige adipocyte thermogenesis

JCI Insight
Activation of brown adipose tissue (BAT) thermogenesis increases energy expenditure and alleviates obesity. Here we discover that histone methyltransferase suppressor of variegation 4–20 homolog 2 (Suv420h2) expression parallels that of Ucp1 in brown and
Xin Cui, Qiang Cao, Fenfen Li, Jia Jing, Zhixue Liu, Xiaosong Yang, Gary J. Schwartz, Liqing Yu, Huidong Shi, Hang Shi, Bingzhong Xue   +10 more
doaj   +1 more source

Thermogenesis in Adipose Tissue: Adrenergic and Non-Adrenergic Pathways. [PDF]

Cells
Hossain MA, Poojari A, Rabiee A.
europepmc   +1 more source