Results 221 to 230 of about 68,485 (306)

SLIT3 fragments orchestrate neurovascular expansion and thermogenesis in brown adipose tissue. [PDF]

open access: yesNat Commun
Serdan TDA   +15 more
europepmc   +1 more source

Single‐Cell Transcriptome‐Wide Mendelian Randomization and Colocalization Uncover Potential Immunocytes‐Related Therapeutic Targets for Obesity

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 9, May 2026.
ABSTRACT Weight‐loss treatment is crucial for individuals with obesity to prevent various complications. The role of Immune cells in obesity has been recently recognized, whereas its translation into therapy requires identifying key target genes. We performed Mendelian randomization (MR) analysis to assess causal relationships between expression ...
Xingjian Zhang   +5 more
wiley   +1 more source

Urine‐Derived iPSC Neurospheres Uncover Proteomic Correlates of Clinical Severity in Dravet Syndrome

open access: yesJournal of Neurochemistry, Volume 170, Issue 5, May 2026.
Urine epithelial cells from Dravet syndrome (DS) patients carrying distinct SCN1A variants were reprogrammed into induced pluripotent stem cells (iPSCs) and differentiated into neural stem cells (NSCs) to generate patient‐derived neurospheres. Three neurosphere lines were analyzed in biological triplicates using isobaric quantitative proteomics ...
Michele Martins   +9 more
wiley   +1 more source

The miR319/bHLH094 Module Regulates Creeping Bentgrass Thermotolerance by Modulating Auxin Biosynthesis and Signalling Pathway

open access: yesPlant Biotechnology Journal, Volume 24, Issue 5, Page 3201-3218, May 2026.
ABSTRACT MicroRNA319 (miR319) has been demonstrated to regulate plant development and responses to stress such as drought and salt. However, its role in thermotolerance, particularly in cool season grasses, remains unclear. Here we report that miR319 plays a negative role in heat tolerance of creeping bentgrass (Agrostis stolonifera).
Kangting Dong   +10 more
wiley   +1 more source

Osteocytes orchestrate browning: emerging signals in bone-fat crosstalk: a systematic review. [PDF]

open access: yesFront Endocrinol (Lausanne)
Anees H   +6 more
europepmc   +1 more source

Adipocyte‐specific FFA2 deletion leads to increased adipose inflammation and is associated with altered intestinal lipid handling in mice

open access: yesPhysiological Reports, Volume 14, Issue 9, May 2026.
Abstract Obesity and related metabolic disorders are often characterized by chronic adipose tissue inflammation, driving systemic insulin resistance and general metabolic dysfunction. Free Fatty Acid Receptor 2 (FFA2) has emerged as a potential modulator of adipocyte function, inflammation, and metabolism.
Chioma Nnyamah   +13 more
wiley   +1 more source

Single intake of matcha increases brown adipose tissue activity in young women with low thermogenesis

open access: yesPhysiological Reports, Volume 14, Issue 9, May 2026.
Abstract Matcha contains several bioactive compounds that contribute to the facilitation of thermogenesis. However, the effects of a single intake of matcha on brown adipose tissue (BAT) activity remain to be elucidated. This study aimed to evaluate the association between matcha intake and BAT activity.
Hirokazu Taniguchi   +4 more
wiley   +1 more source

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