Towards patient-relevant structures: reviewing body-temperature biological macromolecules and their ligands for pharmaceutical applications. [PDF]
Acta Crystallogr D Struct BiolRegulation of pharmaceutical lead compounds does not yet involve the need for patient‐relevant macromolecular structures determined at 37°C; nevertheless, we highlight the advantages of these to ensure chemical relevance and the identification of changes which may occur under physiological conditions.
Brink A, Helliwell JR, Jacobs FJF.
europepmc +2 more sources
Energetics of the Citric Acid Cycle in the Deep Biosphere
Geophysical Monograph Series, Page 303-327., 2020 This book is Open Access. A digital copy can be downloaded for free from Wiley Online Library.
Explores the behavior of carbon in minerals, melts, and fluids under extreme conditions
Carbon trapped in diamonds and carbonate-bearing rocks in subduction zones are examples of the continuing exchange of substantial carbon ...
Peter A. Canovas III, Everett L. Shock
wiley +1 more source
Proton and cadmium adsorption by the archaeon Thermococcus zilligii: Generalising the contrast between thermophiles and mesophiles as sorbents [PDF]
, 2010 Adsorption by microorganisms can play a significant role in the fate and transport of metals in natural systems. Surface complexation models (SCMs) have been applied extensively to describe metal adsorption by mesophilic bacteria, and several recent ...
Bremer, Phil J. +7 more
core +2 more sources
Survival of thermophilic spore-forming bacteria in a 90+ year old milk powder from Ernest Shackelton's Cape Royds Hut in Antarctica [PDF]
, 2000 Milk powder taken to Antarctica on Shackelton's British Antarctic Expedition in 1907 was produced in New Zealand by a roller drying process in the first factory in the world dedicated to this process. Thermophilic bacilli are the dominant contaminants of
Morgan, Hugh W. +2 more
core +5 more sources
Genomic Inference of the Metabolism and Evolution of the Archaeal Phylum Aigarchaeota [PDF]
, 2018 Microbes of the phylum Aigarchaeota are widely distributed in geothermal environments, but their physiological and ecological roles are poorly understood.
Castelle, Cindy J. +14 more
core +3 more sources
Frontiers in Microbiology, 2022 Diverse yet-uncultivated bacteria and archaea, i.e., microbial dark matter, are present in terrestrial hot spring environments. Numerous metagenome-assembled genomes (MAGs) of these uncultivated prokaryotes by short-read metagenomics have been reported ...
Shingo Kato +4 more
doaj +1 more source
Microorganisms, 2021 Thermal ecosystems associated with areas of underground burning coal seams are rare and poorly understood in comparison with geothermal objects. We studied the microbial communities associated with gas vents from the coal-fire in the mining wastes in the
Vitaly V. Kadnikov +5 more
doaj +1 more source
Evidence of global-scale aeolian dispersal and endemism in isolated geothermal microbial communities of Antarctica [PDF]
, 2014 New evidence in aerobiology challenges the assumption that geographical isolation is an effective barrier to microbial transport. However, given the uncertainty with which aerobiological organisms are recruited into existing communities, the ultimate ...
Cary, S. Craig +3 more
core +2 more sources
Microbial Diversity of Terrestrial Geothermal Springs in Armenia and Nagorno-Karabakh: A Review
Microorganisms, 2021 The microbial diversity of high-altitude geothermal springs has been recently assessed to explore their biotechnological potential. However, little is known regarding the microbiota of similar ecosystems located on the Armenian Highland.
Ani Saghatelyan +3 more
doaj +1 more source
Microbial diversity in the thermal springs within Hot Springs National Park [PDF]
, 2018 The thermal water systems of Hot Springs National Park (HSNP) in Hot Springs, Arkansas exist in relative isolation from other North American thermal systems. The HSNP waters could therefore serve as a unique center of thermophilic microbial biodiversity.
Moran, Matthew D +2 more
core +3 more sources