Results 31 to 40 of about 17,622 (218)

Adaptive laboratory evolution of a thermophile toward a reduced growth temperature optimum

Frontiers in Microbiology, 2023
Thermophily is an ancient trait among microorganisms. The molecular principles to sustain high temperatures, however, are often described as adaptations, somewhat implying that they evolved from a non-thermophilic background and that thermophiles, i.e ...
Maria Lehmann, Christoph Prohaska, Benjamin Zeldes, Anja Poehlein, Rolf Daniel, Mirko Basen   +5 more
doaj   +1 more source

Synbiotics for prevention of ventilator-associated pneumonia: a probiotics strain-specific network meta-analysis

Journal of International Medical Research, 2019
Objective Probiotics may be efficacious in preventing ventilator-associated pneumonia (VAP). The aim of this network meta-analysis (NMA) was to clarify the efficacy of different types of probiotics for preventing VAP.
Qiong-Li Fan, Xiu-Mei Yu, Quan-Xing Liu, Wang Yang, Qin Chang, Yu-Ping Zhang   +5 more
doaj   +1 more source

Quorum sensing in thermophiles: prevalence of autoinducer-2 system

BMC Microbiology, 2018
Background Quorum sensing is a mechanism of cell to cell communication that requires the production and detection of signaling molecules called autoinducers.
Amandeep Kaur, Neena Capalash, Prince Sharma   +2 more
doaj   +1 more source

Genomic Analysis Provides New Insights Into Biotechnological and Industrial Potential of Parageobacillus thermantarcticus M1

Frontiers in Microbiology, 2022
Parageobacillus thermantarcticus strain M1 is a Gram-positive, motile, facultative anaerobic, spore forming, and thermophilic bacterium, isolated from geothermal soil of the crater of Mount Melbourne (74°22′ S, 164°40′ E) during the Italian Antarctic ...
Songul Yasar Yildiz, Ilaria Finore, Luigi Leone, Ida Romano, Licia Lama, Ceyda Kasavi, Barbara Nicolaus, Ebru Toksoy Oner, Annarita Poli   +8 more
doaj   +1 more source

PCA‐Based Database Mining Enables the Discovery of Bacterial Carbene Transferases for Stereodivergent Cyclopropanation

Angewandte Chemie, Volume 138, Issue 10, 2 March 2026.
Database mining using principal component analysis (PCA)‐based clustering enabled discovery of bacterial enzymes capable of catalyzing stereodivergent cyclopropanation of styrene. Statistical analyses of sequence data further revealed characteristic structural properties of these enzymes, highlighting the potential of the bioinformatics tools for ...
Shunsuke Kato, Koki Takeuchi, Kohei Umeda, Hisashi Kudo, Tomohisa Hasunuma, Takashi Hayashi   +5 more
wiley   +2 more sources

Genomic Inference of the Metabolism and Evolution of the Archaeal Phylum Aigarchaeota [PDF]

, 2018
Microbes of the phylum Aigarchaeota are widely distributed in geothermal environments, but their physiological and ecological roles are poorly understood.
Castelle, Cindy J., Hedlund, Brian P., Hua, Zheng-Shuang, Knight, Rob, Li, Wen-Jun, Li, Yu-Xian, Liu, Lan, Qi, Yan-Ling, Qu, Yan-Ni, Rao, Yang-Zhi, Shu, Wen-Sheng, Tian, Ye, Yin, Yi-Rui, Zhou, En-Min, Zhu, Qiyun   +14 more
core   +3 more sources

Biallelic mutations in valyl-tRNA synthetase gene VARS are associated with a progressive neurodevelopmental epileptic encephalopathy. [PDF]

, 2019
Aminoacyl-tRNA synthetases (ARSs) function to transfer amino acids to cognate tRNA molecules, which are required for protein translation. To date, biallelic mutations in 31 ARS genes are known to cause recessive, early-onset severe multi-organ diseases ...
Accogli, Andrea, Ben-Omran, Tawfeg, Bernard, Geneviève, Chowdhury, Shimul, Crawford, John R, Dimmock, David, Friedman, Jennifer, Gleeson, Joseph G, Guerrero, Kether, Hildreth, Amber, Issa, Mahmoud Y, James, Kiely N, Kingsmore, Stephen F, Koehler, Alanna E, Lo, Wing-Sze, Mendes, Marisa I, Musaev, Damir, Nahas, Shareef, Omar, Tarek EI, Salomons, Gajja S, Smith, Desiree E, Stanley, Valentina, Tran, Luan T, Wang, Rengang, Wigby, Kristen, Wright, Meredith S, Xu, Zhiwen, Zaki, Maha S, Zhai, Liting   +28 more
core   +2 more sources

Purification and Reconstitution of the Glutamate Carrier GltT of the Thermophilic Bacterium Bacillus stearothermophilus [PDF]

, 1995
An affinity tag consisting of six adjacent histidine residues followed by an enterokinase cleavage site was genetically engineered at the N-terminus of the glutamate transport protein GltT of the thermophilic bacterium Bacillus stearothermophilus.
Bassilana M., Deguchi Y., Heyne R. I. R., Hirata H., Hochuli E., Kaback H. R., Knol J., Lolkema J. S., Lolkema J. S., Newman M. J., Pines G., Poolman B., Pos K. M., Rigaud J.-L., Ruan Z.-S., Sambrook J., Tolner B., Tolner B., Tolner B., Zhang Y.   +19 more
core   +2 more sources

Thermophilic lignocellulose deconstruction [PDF]

FEMS Microbiology Reviews, 2014
Thermophilic microorganisms are attractive candidates for conversion of lignocellulose to biofuels because they produce robust, effective, carbohydrate-degrading enzymes and survive under harsh bioprocessing conditions that reflect their natural biotopes.
Sara E, Blumer-Schuette, Steven D, Brown, Kyle B, Sander, Edward A, Bayer, Irina, Kataeva, Jeffrey V, Zurawski, Jonathan M, Conway, Michael W W, Adams, Robert M, Kelly   +8 more
openaire   +2 more sources

Comparative analysis of thermophilic and mesophilic proteins using Protein Energy Networks

BMC Bioinformatics, 2010
Background Thermophilic proteins sustain themselves and function at higher temperatures. Despite their structural and functional similarities with their mesophilic homologues, they show enhanced stability.
Vishveshwara Saraswathi, Vijayabaskar MS
doaj   +1 more source