Results 81 to 90 of about 1,942 (214)

Genetics‐Based Targeting Strategies for Precise Neuromodulation

Advanced Science, Volume 12, Issue 28, July 24, 2025.
In this Review, the fundamental principles and implementation protocols of genetics‐based precision neuromodulation are first introduced. Then, wireless and low‐invasive strategies based on nano‐transducing materials are highlighted, along with a dissection and analysis of the strengths and weaknesses of representative studies.
Yuyuan He, Zhidong Wei, Jianda Xu, Fei Jin, Tong Li, Lili Qian, Juan Ma, Weiying Zheng, Negar Javanmardi, Ting Wang, Kangjian Sun, Zhang‐Qi Feng   +11 more
wiley   +1 more source

OXYGEN GRADIENTS CAUSE PATTERN ORIENTATION IN DICTYOSTELIUM CELL CLUMPS [PDF]

, 1981
We have investigated the formation of the prestalk-prespore pattern in Dictyottelium discoideum. Pattern formation occurs in clumps of Dictyostelium cells embedded in agar under a 100% oxygen atmosphere.
David, Charles N., Sternfeld, John
core  

RETINOBLASTOMA‐RELATED Has Both Canonical and Noncanonical Regulatory Functions During Thermo‐Morphogenic Responses in Arabidopsis Seedlings

Plant, Cell &Environment, Volume 48, Issue 2, Page 1217-1231, February 2025.
ABSTRACT Warm temperatures accelerate plant growth, but the underlying molecular mechanism is not fully understood. Here, we show that increasing the temperature from 22°C to 28°C rapidly activates proliferation in the apical shoot and root meristems of wild‐type Arabidopsis seedlings.
Rasik Shiekh Bin Hamid, Fruzsina Nagy, Nikolett Kaszler, Ildikó Domonkos, Magdolna Gombos, Annamária Marton, Csaba Vizler, Eszter Molnár, Aladár Pettkó‐Szandtner, László Bögre, Attila Fehér, Zoltán Magyar   +11 more
wiley   +1 more source

Heat application in live cell imaging

FEBS Open Bio, Volume 14, Issue 12, Page 1940-1954, December 2024.
Thermal modulation in live‐cell imaging with a high spatiotemporal resolution allows the investigation of biomolecular reactions like protein deactivation and unfolding, and cellular processes like calcium signaling. Local changes in temperature are induced via infrared (IR) irradiation of water (direct), magnetic or radiative excitation of absorber ...
Linda Sistemich, Simon Ebbinghaus
wiley   +1 more source

Molecular mechanisms of thermosensation

Folia Pharmacologica Japonica, 2004
We feel a wide range of temperatures spanning from cold to heat. Within this range, temperatures over about 43 degrees C and below about 15 degrees C evoke not only a thermal sensation, but also a feeling of pain. In mammals, six thermosensitive ion channels have been reported, all of which belong to the TRP (transient receptor potential) super family.
openaire   +3 more sources

The secreted autotransporter toxin (Sat) does not act as a virulence factor in the probiotic Escherichia coli strain Nissle 1917 [PDF]

, 2015
BACKGROUND: Escherichia coli Nissle 1917 (EcN) is a probiotic used in the treatment of intestinal diseases. Although it is considered safe, EcN is closely related to the uropathogenic E.
Aguilera Gil, Maria Laura, Alvarez Villagomez, Carina Shianya, Badía Palacín, Josefa, Baldomà Llavinés, Laura, Cañas Pacheco, María Alexandra, Fábrega Fernández, María José, Giménez Claudio, Rosa, Martín Venegas, Raquel, Toloza Maturana, Lorena   +8 more
core   +1 more source

Unlocking the therapeutic potential of TRPV3: Insights into thermosensation, channel modulation, and skin homeostasis involving TRPV3

BioEssays, Volume 46, Issue 7, July 2024.
TRPV3, a warmth sensor, plays a role in maintaining skin homeostasis. The discovery of membrane protein TMEM79 modulation on TRPV3 in keratinocytes underscores their role in warmth sensation. Thus, comprehensive understanding of TRPV3 in physiology and pathology yields insight into skin function.
Jing Lei, Makoto Tominaga
wiley   +1 more source

'Add, stir and reduce': Yersinia spp. as model bacteria for pathogen evolution [PDF]

, 2016
In the study of molecular microbiology and bacterial genetics, pathogenic species of the Yersinia genus have been pillars for research aimed at understanding how bacteria evolve into mammalian pathogens.
McNally, A, Reuter, S, Thomson, NR, Wren, BW   +3 more
core   +4 more sources

Measurement and Control of Single Nitrogen-Vacancy Center Spins above 600 K

, 2012
We study the spin and orbital dynamics of single nitrogen-vacancy (NV) centers in diamond between room temperature and 700 K. We find that the ability to optically address and coherently control single spins above room temperature is limited by ...
Alkauskas, A., Awschalom, D. D., Buckley, B. B., Christle, D. J., Toyli, D. M., Van de Walle, C. G.   +5 more
core   +2 more sources

Intrinsic Thermal Sensing Controls Proteolysis of Yersinia Virulence Regulator RovA [PDF]

, 2009
Pathogens, which alternate between environmental reservoirs and a mammalian host, frequently use thermal sensing devices to adjust virulence gene expression. Here, we identify the Yersinia virulence regulator RovA as a protein thermometer. Thermal shifts
A Lupas, AK Heroven, AK Heroven, AK Heroven, AK Heroven, AL Goldberg, Ann Kathrin Heroven, Ariane Zimmermann, DA Parsell, DW Ellison, DW Ellison, E Gur, EJ Bottone, G Nagel, G Zhao, HC Huang, HJ Koornhof, HJ Tran, I Bolin, I Lee, IM Shah, IM Shah, JM Flynn, JR Rohde, JS Cathelyn, K Nomura, KA Datsenko, Katharina Herbst, KC Keiler, KH Wang, L Wang, M Gonzalez, M Marceau, M Pruteanu, Martin Weichert, Matthias Bujara, MB Lawrenz, ME Konkel, MW Jackson, NC Stenseth, NP Hoe, NR Thomson, O Gal-Mor, P Legault, P Servant, PA Revell, Petra Dersch, R Hurme, Ralph R. Isberg, RT Sauer, S Gottesman, S Licht, SC Straley, SG Rudyak, SP Wilkinson, TA Baker, TA Phillips, V Tsilibaris, VL Motin, W Schumann, Wiebke Opitz   +60 more
core   +4 more sources