Results 81 to 90 of about 2,069 (218)

Tackling thermosensation with multidimensional phenotyping [PDF]

BMC Biology, 2012
Most if not all animals sense temperature using specialized thermosensory neurons. Genetic studies in simple organisms have been used to identify gene products required for detecting temperature changes or for mediating the effects of temperature on behaviour.
openaire   +4 more sources

Novel functions and regulation of cryptic cellobiose operons in Escherichia coli [PDF]

, 2015
Presence of cellobiose as a sole carbon source induces mutations in the chb and asc operons of Escherichia coli and allows it to grow on cellobiose. We previously engineered these two operons with synthetic constitutive promoters and achieved efficient ...
A Daddaoua, AH Kachroo, BG Hall, D Na, E Scotto-Lavino, FR Blattner, G Neelakanta, K Kochanowski, K-K Cheng, KA Datsenko, M Dwidar, M Ito, MD Rolfe, N Saito, NO Keyhani, P Vinuselvi, Patrick C. Cirino, PP Cherepanov, Q Hua, R Raghavan, S Datta, SA Leyn, Sung Kuk Lee, T Conrad, TR Raghunand, V Parisutham, Vinuselvi Parisutham, WG Miller, YS Ryu   +28 more
core   +3 more sources

Identification of Novel Thermosensors in Gram-Positive Pathogens

Frontiers in Molecular Biosciences, 2020
Temperature is a crucial variable that every living organism, from bacteria to humans, need to sense and respond to in order to adapt and survive. In particular, pathogenic bacteria exploit host-temperature sensing as a cue for triggering virulence gene ...
Pilar Fernández, Alejandra Raquel Díaz, María Florencia Ré, Lucía Porrini, Diego de Mendoza, Diego de Mendoza, Daniela Albanesi, Daniela Albanesi, María Cecilia Mansilla, María Cecilia Mansilla   +9 more
doaj   +1 more source

Thermoreceptors: Recent heat in thermosensation [PDF]

Current Biology, 1997
Every organism with a nervous system can detect changes in temperature. Recent studies on sensory neurons from rats and genetic evidence from nematodes have provided intriguing hints about the molecular basis of thermosensation.
openaire   +3 more sources

The molecular and cellular basis of thermosensation in mammals [PDF]

Current Opinion in Neurobiology, 2015
Over a decade and a half of intensive study has shown that the Transient Receptor Potential family ion channels TRPV1 and TRPM8 are the primary sensors of heat and cold temperatures in the peripheral nervous system. TRPV homologues and TRPA1 are also implicated, but recent genetic evidence has diminished their significance in thermosensation and ...
Erika K. Lippoldt, David D. McKemy, Radhika Palkar   +2 more
openaire   +3 more sources

Intrinsic Thermal Sensing Controls Proteolysis of Yersinia Virulence Regulator RovA [PDF]

, 2009
Pathogens, which alternate between environmental reservoirs and a mammalian host, frequently use thermal sensing devices to adjust virulence gene expression. Here, we identify the Yersinia virulence regulator RovA as a protein thermometer. Thermal shifts
A Lupas, AK Heroven, AK Heroven, AK Heroven, AK Heroven, AL Goldberg, Ann Kathrin Heroven, Ariane Zimmermann, DA Parsell, DW Ellison, DW Ellison, E Gur, EJ Bottone, G Nagel, G Zhao, HC Huang, HJ Koornhof, HJ Tran, I Bolin, I Lee, IM Shah, IM Shah, JM Flynn, JR Rohde, JS Cathelyn, K Nomura, KA Datsenko, Katharina Herbst, KC Keiler, KH Wang, L Wang, M Gonzalez, M Marceau, M Pruteanu, Martin Weichert, Matthias Bujara, MB Lawrenz, ME Konkel, MW Jackson, NC Stenseth, NP Hoe, NR Thomson, O Gal-Mor, P Legault, P Servant, PA Revell, Petra Dersch, R Hurme, Ralph R. Isberg, RT Sauer, S Gottesman, S Licht, SC Straley, SG Rudyak, SP Wilkinson, TA Baker, TA Phillips, V Tsilibaris, VL Motin, W Schumann, Wiebke Opitz   +60 more
core   +4 more sources

Novel hypercapsulation RNA thermosensor variants in Neisseria meningitidis and their association with invasive meningococcal disease: a genetic and phenotypic investigation and molecular epidemiological study

The Lancet Microbe, 2020
Summary: Background: Neisseria meningitidis is the causative agent of invasive meningococcal disease and the polysaccharide capsule is one of its major virulence factors.
Jens Karlsson, MSc, Hannes Eichner, MSc, Cecilia Andersson, BSc, Susanne Jacobsson, PhD, Edmund Loh, PhD   +4 more
doaj   +1 more source

Flame‐Retardant Ionogel Enabled by Lignin Molecular Networks for Fire Rescue

Advanced Science, EarlyView.
Wearable sensors for harsh, high‐temperature, fire‐prone environments face challenges in heat resistance and stability. This study introduces a flame‐retardant, waterproof glycol lignin ionogel (GLI) with a robust 3D network, exceptional tensile strength, strong adhesion, biocompatibility, eco‐safety, and dual temperature‐motion sensing, even after ...
Zewei Ye, Haomeng Yu, Hongxia Xie, Wenwen Zhu, Shitao Shi, Chencong Liu, Yuanyuan Wang, Jiaqi Liao, Qingfeng Sun, Dawei Zhao, Xiaoping Shen   +10 more
wiley   +1 more source

Functional assessment of temperature-gated ion-channel activity using a real-time PCR machine

BioTechniques, 2009
The functional activity of a number of ion channels is highly sensitive to large changes in temperature. Foremost among these are the thermosensing TRP channels which include cold- (TRPM8, TRPA1), warmth- (TRPV3, TRPV4), and heat-sensing (TRPV1, TRPV2 ...
Derek S. Reubish, Daniel E. Emerling, Jeff DeFalco, Daniel Steiger, Cheryl L. Victoria, Fabien Vincent   +5 more
doaj   +1 more source

An epigenomic threshold hypothesis for integrating dynamic environmental signals into functional models of developmental polyphenisms

Functional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Interactions between developing embryos and a multitude of environmental factors (e.g. climate, nutrition, social cues, stress and anthropogenic contaminants) underlie adaptive and non‐adaptive developmental plasticity and carry broad implications across ecological ...
Benjamin B. Parrott, Samantha L. Bock
wiley   +1 more source