Results 81 to 90 of about 1,420 (168)

Carboxamido steroids inhibit the opening properties of transient receptor potential ion channels by lipid raft modulation

Journal of Lipid Research, 2018
Transient Receptor Potential (TRP) cation channels, like the TRP Vanilloid 1 (TRPV1) and TRP Ankyrin 1 (TRPA1), are expressed on primary sensory neurons. These thermosensor channels play a role in pain processing.
Éva Sághy, Maja Payrits, Tünde Bíró-Sütő, Rita Skoda-Földes, Eszter Szánti-Pintér, János Erostyák, Géza Makkai, György Sétáló, Jr., László Kollár, Tamás Kőszegi, Rita Csepregi, János Szolcsányi, Zsuzsanna Helyes, Éva Szőke   +13 more
doaj   +1 more source

Welcome Pathogens: Transient Heat Dampens Immune Responses to Acibenzolar‐S‐Methyl in Apple Plants

Plant, Cell &Environment, Volume 49, Issue 3, Page 1229-1248, March 2026.
ABSTRACT Climate change affects plant‐pathogen interactions, with disease outcome varying depending on the pathosystem and environmental scenario. In Arabidopsis, a thermo‐sensitive module of salicylic acid (SA) signalling makes immunity vulnerable to heat.
Erwan Chavonet, Bao‐huynh Nguyen, Christelle Heintz, Raphaël Cournol, Jitka Široká, Ondřej Novák, Romain Larbat, Matthieu Gaucher, Marie‐Noëlle Brisset, Florent Pantin, Alexandre Degrave   +10 more
wiley   +1 more source

Single‐Cell Hyperthermia: Diamond Quantum Thermometry Reveals Thermal Control of Macrophage Polarization

Advanced Materials, Volume 38, Issue 8, 6 February 2026.
Photothermal nanodiamonds with quantum sensing capabilities generate lysosome‐confined hyperthermia, enabling simultaneous temperature and radical detection via diamond sensing. This localized thermal and oxidative stress drives pro‐inflammatory (M1) macrophage polarization, revealing a new strategy for precision immunomodulation through subcellular ...
Kaiqi Wu, Qi Lu, Yong Ren, Priyadharshini Balasubramanian, Kazem Ebadi Jalal, Hannah Klug, Matthias Klein, Toszka Bohn, Tobias Bopp, Fedor Jelezko, Yingke Wu, Tanja Weil   +11 more
wiley   +1 more source

SUPER: Upcycling Genetic Parts for Precise Gene Expression Control, Leakage Minimization, and Genetic Circuit Stability

Advanced Science, Volume 13, Issue 12, 27 February 2026.
To precisely modulate natural and synthetic regulatory parts, SUPER is introduced as a sophisticated and tunable controller of genetic devices without requiring sequence modification on the target. SUPER enhances dynamic range of RNA‐, chemical‐, temperature‐, and protein‐responsive biosensors up to 1011%, and converts biosensors to cover an expanded ...
Taeyang Heo, Dongwon Park, Woosub Shin, Jongmin Kim   +3 more
wiley   +1 more source

Solid-like condensation of MORF8 inhibits RNA editing under heat stress in Arabidopsis

Nature Communications
Heat stress inhibits photosynthesis efficiency, thereby suppressing plant growth and crop yield. However, the mechanism underlying this inhibition is not fully understood.
Jie Wu, Yue Wang, Haodong Chen, Tongda Xu, Wenqiang Yang, Xiaofeng Fang   +5 more
doaj   +1 more source

Change in intraoperative rectal temperature influencing erectile dysfunction following transurethral resection of the prostate

Journal of the Formosan Medical Association, 2012
In this study, we assessed the relationship between changes in intraoperative rectal temperature and erectile function in patients who have undergone transurethral resection of the prostate.
Chih-Kuang Liu, Chun-Hou Liao, Kong-Sang Wan, Wen-Kai Lee, Huey-Sheng Jeng, Ben-Chang Shia, Chu-Chieh Chen, Ming-Chung Ko   +7 more
doaj   +1 more source

Integrative signaling networks of membrane guanylate cyclases: Biochemistry and physiology

Frontiers in Molecular Neuroscience, 2016
This monograph presents a historical perspective of cornerstone developments on the biochemistry and physiology of mammalian membrane guanylate cyclases (MGCs), highlighting contributions made by the authors and their collaborators.
Rameshwar K Sharma, Teresa Duda, Clint L Makino   +2 more
doaj   +1 more source

Corrigendum: Identification of novel thermosensors in gram-positive pathogens

Frontiers in Molecular Biosciences, 2022
Pilar Fernández, Alejandra Raquel Díaz, María Florencia Ré, Lucía Porrini, Diego de Mendoza, Diego de Mendoza, Daniela Albanesi, Daniela Albanesi, María Cecilia Mansilla, María Cecilia Mansilla   +9 more
doaj   +1 more source

Photobody formation spatially segregates two opposing phytochrome B signaling actions of PIF5 degradation and stabilization

Nature Communications
Photoactivation of the plant photoreceptor and thermosensor phytochrome B (PHYB) triggers its condensation into subnuclear membraneless organelles named photobodies (PBs). However, the function of PBs in PHYB signaling remains frustratingly elusive. Here,
Ruth Jean Ae Kim, De Fan, Jiangman He, Keunhwa Kim, Juan Du, Meng Chen   +5 more
doaj   +1 more source

Distinguishing individual photobodies using Oligopaints reveals thermo-sensitive and -insensitive phytochrome B condensation at distinct subnuclear locations

Nature Communications
Photobodies (PBs) are membraneless subnuclear organelles that self-assemble via concentration-dependent liquid-liquid phase separation (LLPS) of the plant photoreceptor and thermosensor phytochrome B (PHYB).
Juan Du, Keunhwa Kim, Meng Chen
doaj   +1 more source