Results 61 to 70 of about 1,415 (167)

Concerted actions of a thermo-labile regulator and a unique intergenic RNA thermosensor control Yersinia virulence.

open access: yesPLoS Pathogens, 2012
Expression of all Yersinia pathogenicity factors encoded on the virulence plasmid, including the yop effector and the ysc type III secretion genes, is controlled by the transcriptional activator LcrF in response to temperature.
Katja Böhme   +10 more
doaj   +1 more source

The antennal transcriptome of Triatoma infestans reveals substantial expression changes triggered by a blood meal

open access: yesBMC Genomics, 2022
Background Triatoma infestans is the main vector of Chagas disease in the Americas, currently transmitting it in Argentina, Paraguay, and Bolivia. Many T. infestans populations present insecticide resistance, reducing the efficiency of control campaigns.
Jose Manuel Latorre Estivalis   +3 more
doaj   +1 more source

Pharmacological manipulation of the immediate effects of spinal trauma in neonatal rats reveals a crucial role for TRPV4 receptors

open access: yesThe Journal of Physiology, Volume 604, Issue 7, Page 3077-3093, 1 April 2026.
Abstract figure legend A, schematic illustration of the ventral aspect of an ex vivo preparation of the entire CNS from a neonatal rat subjected to a calibrated thoracic impact. The trauma induced a large depolarising injury potential (DIP, black trace) recorded from the L5 ventral root (VRrL5), which was markedly reduced by transient receptor ...
Atiyeh Mohammadshirazi   +5 more
wiley   +1 more source

Molecular Responses to Climate Change: How Warming and Acidification Reshape the Proteome and Phosphoproteome of the Endangered Mira Chub

open access: yesEcology and Evolution, Volume 16, Issue 3, March 2026.
ABSTRACT Global environmental change affects organisms, including their physiology. In freshwater ecosystems, where migration is limited, populations often rely on phenotypic plasticity to respond. While transcriptomics has been widely used to study stress responses at the molecular level, less is known about the proteome, which reflects post ...
João M. Moreno   +5 more
wiley   +1 more source

Structural plasticity and catalysis regulation of a thermosensor histidine kinase [PDF]

open access: yesProceedings of the National Academy of Sciences, 2009
Temperature sensing is essential for the survival of living cells. A major challenge is to understand how a biological thermometer processes thermal information to optimize cellular functions. Using structural and biochemical approaches, we show that the thermosensitive histidine kinase, DesK, from Bacillus ...
Albanesi, Daniela   +7 more
openaire   +2 more sources

Noninvasive 11.7‐T Magnetic Resonance Spectroscopy and Imaging Reveals Retinal Metabolic Alterations Induced by Blue Light Exposure

open access: yesNMR in Biomedicine, Volume 39, Issue 3, March 2026.
Retinal metabolic changes were analyzed using proton magnetic resonance spectroscopy (1H‐MRS), marking an initial application of this non‐invasive method on living eyes. Key metabolites were identified within the retinal region of adult rats. The observed changes following intense blue light exposure were predominantly attributable to the retina, as it
Lacramioara Samoila   +10 more
wiley   +1 more source

Carboxamido steroids inhibit the opening properties of transient receptor potential ion channels by lipid raft modulation

open access: yesJournal of Lipid Research, 2018
Transient Receptor Potential (TRP) cation channels, like the TRP Vanilloid 1 (TRPV1) and TRP Ankyrin 1 (TRPA1), are expressed on primary sensory neurons. These thermosensor channels play a role in pain processing.
Éva Sághy   +13 more
doaj   +1 more source

Novel hypercapsulation RNA thermosensor variants in Neisseria meningitidis and their association with invasive meningococcal disease: a genetic and phenotypic investigation and molecular epidemiological study

open access: yesThe Lancet Microbe, 2020
Summary: Background: Neisseria meningitidis is the causative agent of invasive meningococcal disease and the polysaccharide capsule is one of its major virulence factors.
Jens Karlsson, MSc   +4 more
doaj   +1 more source

Welcome Pathogens: Transient Heat Dampens Immune Responses to Acibenzolar‐S‐Methyl in Apple Plants

open access: yesPlant, Cell &Environment, Volume 49, Issue 3, Page 1229-1248, March 2026.
ABSTRACT Climate change affects plant‐pathogen interactions, with disease outcome varying depending on the pathosystem and environmental scenario. In Arabidopsis, a thermo‐sensitive module of salicylic acid (SA) signalling makes immunity vulnerable to heat.
Erwan Chavonet   +10 more
wiley   +1 more source

Single‐Cell Hyperthermia: Diamond Quantum Thermometry Reveals Thermal Control of Macrophage Polarization

open access: yesAdvanced Materials, Volume 38, Issue 8, 6 February 2026.
Photothermal nanodiamonds with quantum sensing capabilities generate lysosome‐confined hyperthermia, enabling simultaneous temperature and radical detection via diamond sensing. This localized thermal and oxidative stress drives pro‐inflammatory (M1) macrophage polarization, revealing a new strategy for precision immunomodulation through subcellular ...
Kaiqi Wu   +11 more
wiley   +1 more source

Home - About - Disclaimer - Privacy