Results 71 to 80 of about 1,420 (168)

A genome-wide survey of highly expressed non-coding RNAs and biological validation of selected candidates in Agrobacterium tumefaciens. [PDF]

open access: yesPLoS ONE, 2013
Agrobacterium tumefaciens is a plant pathogen that has the natural ability of delivering and integrating a piece of its own DNA into plant genome. Although bacterial non-coding RNAs (ncRNAs) have been shown to regulate various biological processes ...
Keunsub Lee   +7 more
doaj   +1 more source

Conkazal‐M1 from the MKAVA family of conotoxins: A dual‐function protease inhibitor and neuroactive peptide

open access: yesProtein Science, Volume 35, Issue 5, May 2026.
Abstract Marine cone snails produce a diverse array of bioactive peptides, known as conotoxins, in their venom. Given their high target potency and specificity, conotoxins are attractive compounds for the development of precision research tools and pharmacological agents.
Celeste M. Hackney   +12 more
wiley   +1 more source

Thermosensors in eubacteria: role and evolution

open access: yesJournal of Biosciences, 2007
Temperature is an important physical stress factor sensed by bacteria and used to regulate gene expression. Three different macromolecules have been identified being able to sense temperature: DNA, mRNA and proteins. Depending on the induction mechanism, two different pathways have to be distinguished, namely the heat shock response and the high ...
openaire   +2 more sources

The antennal transcriptome of Triatoma infestans reveals substantial expression changes triggered by a blood meal

open access: yesBMC Genomics, 2022
Background Triatoma infestans is the main vector of Chagas disease in the Americas, currently transmitting it in Argentina, Paraguay, and Bolivia. Many T. infestans populations present insecticide resistance, reducing the efficiency of control campaigns.
Jose Manuel Latorre Estivalis   +3 more
doaj   +1 more source

Cross‐Depth Genetic Connectivity Supports the Role of Deep Kelp Forests as Refuge From Climate Change

open access: yesDiversity and Distributions, Volume 32, Issue 5, May 2026.
ABSTRACT Aim Ocean warming and marine heatwaves are threatening the persistence of kelp forests, but cooler, deeper reefs might act as refuges from which shallow populations can recover. This study aimed to assess the genetic connectivity, diversity, and adaptive structure of deep kelp reefs to evaluate their potential as climate refuges.
Antoine J. P. Minne   +4 more
wiley   +1 more source

Pharmacological manipulation of the immediate effects of spinal trauma in neonatal rats reveals a crucial role for TRPV4 receptors

open access: yesThe Journal of Physiology, Volume 604, Issue 7, Page 3077-3093, 1 April 2026.
Abstract figure legend A, schematic illustration of the ventral aspect of an ex vivo preparation of the entire CNS from a neonatal rat subjected to a calibrated thoracic impact. The trauma induced a large depolarising injury potential (DIP, black trace) recorded from the L5 ventral root (VRrL5), which was markedly reduced by transient receptor ...
Atiyeh Mohammadshirazi   +5 more
wiley   +1 more source

Structural plasticity and catalysis regulation of a thermosensor histidine kinase [PDF]

open access: yesProceedings of the National Academy of Sciences, 2009
Temperature sensing is essential for the survival of living cells. A major challenge is to understand how a biological thermometer processes thermal information to optimize cellular functions. Using structural and biochemical approaches, we show that the thermosensitive histidine kinase, DesK, from Bacillus ...
Albanesi, Daniela   +7 more
openaire   +2 more sources

Molecular Responses to Climate Change: How Warming and Acidification Reshape the Proteome and Phosphoproteome of the Endangered Mira Chub

open access: yesEcology and Evolution, Volume 16, Issue 3, March 2026.
ABSTRACT Global environmental change affects organisms, including their physiology. In freshwater ecosystems, where migration is limited, populations often rely on phenotypic plasticity to respond. While transcriptomics has been widely used to study stress responses at the molecular level, less is known about the proteome, which reflects post ...
João M. Moreno   +5 more
wiley   +1 more source

Noninvasive 11.7‐T Magnetic Resonance Spectroscopy and Imaging Reveals Retinal Metabolic Alterations Induced by Blue Light Exposure

open access: yesNMR in Biomedicine, Volume 39, Issue 3, March 2026.
Retinal metabolic changes were analyzed using proton magnetic resonance spectroscopy (1H‐MRS), marking an initial application of this non‐invasive method on living eyes. Key metabolites were identified within the retinal region of adult rats. The observed changes following intense blue light exposure were predominantly attributable to the retina, as it
Lacramioara Samoila   +10 more
wiley   +1 more source

Structure and Function of the Escherichia coli Thermosensors.

open access: yesSeibutsu Butsuri, 1999
Thermotaxis in Escherichia coli as a model system for studying thermosensing mechanisms. All the components involved in the signal transduction circuit have been indentified. Thermosensors are the transmembrane proteins that were originally indentified as chemoreceptors. They regulate the activity of the cytoplasmic histidine kinase CheA.
NISHIYAMA, So-ichiro   +2 more
openaire   +1 more source

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