Results 31 to 40 of about 37,114 (274)

Radiosynthesis of 5-[¹⁸F]Fluoro-1,2,3-triazoles through Aqueous Iodine–[¹⁸F]Fluorine Exchange Reaction

Molecules, 2021
In this report, a simple and efficient process to achieve fluorine-18-labeled 1,2,3-triazole is reported. The heteroaromatic radiofluorination was successfully achieved through an iodine–fluorine-18 exchange in an aqueous medium requiring only trace ...
Xiang Zhang, Falguni Basuli, Sameh Abdelwahed, Tadhg Begley, Rolf Swenson   +4 more
doaj   +1 more source

B vitamins in diseases of the nervous system - facts and myths

Journal of Education, Health and Sport, 2023
Introduction: B vitamins are necessary for the proper functioning of the nervous system, taking part in the synthesis of neurotransmitters, RNA and DNA and acting as cofactors in many cellular metabolic pathways.
Damian Jasłowski
doaj   +1 more source

Dietary intake, nutritional status and mental wellbeing of homeless adults in Reading, UK [PDF]

, 2017
Malnutrition has been reported in the homeless, yet the specific nutritional issues faced by each homeless community are unclear. This is in part due to nutrient intake often being compared with dietary reference values as opposed to a comparative housed
Charlotte Mortin, Darnton-Hill, Hoyumpa, Hwang, Josephine V. Seale, Julie A. Lovegrove, Lisha Armstrong, Luder, Lykkesfeldt, McKeown, Rosalind Fallaize, Tarasuk, Wolgemuth   +12 more
core   +3 more sources

Protein Language Model‐Guided Engineering of a 2,3‐Butanediol Dehydrogenase for the Enantioselective Synthesis of Cyclic α‐Hydroxy Ketones

Advanced Science, EarlyView.
A (2R,3R)‐butanediol dehydrogenase from Bacillus subtilis (BsBDH) is engineered for the enantioselective synthesis of 2‐hydroxycyclohexanone. A PASS computational design strategy is proposed to enhance the thermostability of BsBDH. Moreover, ESM‐1v combined with ISM is utilized for enhancing and inverting its stereoselectivity.
Haote Ding, Ling Jiang, Yijia Song, Zhongji Pu, Lirong Yang, Haoran Yu   +5 more
wiley   +1 more source

Anatomy of corpus callosum in prenatally malnourished rats [PDF]

, 2012
Indexación: Web of Science; ScieloThe effect of prenatal malnutrition on the anatomy of the corpus callosum was assessed in adult rats (45-52 days old).
Aboitiz, Francisco, Flores, Osvaldo, Gil, Julio, Gimeno, Miguel, Hernandez, Alejandro, Laborda, Jesús, Morgan, Carlos, Olivares, Ricardo, Ortiz, Alexis, Pérez, Hernan, Soto-Moyano, Ruben   +10 more
core   +2 more sources

Engineering New‐to‐Nature Biological Pathways for β,γ‐Alkanediol Synthesis

Advanced Science, EarlyView.
β,γ‐Alkanediols are value‐added chemicals to be used as functional solvents, biofuels, and cosmetic components. This work demonstrates a carboligation‐mediated approach for synthesis of linear chain β,γ‐alkanediols in Escherichia coli, namely, hexane‐2,3‐diol (2,3‐HDO) and pentane‐2,3‐diol (2,3‐PDO). The engineered E. coli cells produce 152.2 mm (17.98
Haofeng Chen, Haidong Yu, Dongjiang Lin, Guojun Yang, Yuchen Xie, Yang Zhang, Jifeng Yuan   +6 more
wiley   +1 more source

Impact of Rapid Exome Sequencing on Pediatric Patients With Cardiomyopathy and Acute Heart Failure

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Few studies describe the impact of rapid exome sequencing (ES) on pediatric cardiomyopathy in urgent clinical settings. Here, we retrospectively report the impact of rapid singleton ES in pediatric patients presented with acute heart failure and isolated cardiomyopathy or myocarditis, between 2021 and 2023 at a single tertiary care center.
Tameemi Abdalla Moady, Tova Hershkovitz, Clair Habib, Ori Attias, Amir Hadash, Galit Tal, Asaad Khoury, Josef Ben‐Ari, Danny Eytan, Tamar Paperna, Karin Weiss   +10 more
wiley   +1 more source

Dietary Mannan‐Rich Fractions Attenuate Weaning Stress in Piglets via Modulating Gut Microbiota and TLR5/NF‐κB Signaling

Animal Research and One Health, EarlyView.
This study aimed to investigate the potential of a mannan‐rich fraction (MRF) as a dietary intervention to alleviate weaning stress in piglets. Our results revealed that MRF could alleviate weaning stress by modulating the gut microbiota and the TLR5/NF‐κB signaling pathway, offering a novel and sustainable alternative to antibiotic use in swine ...
Yutong Lu, Yiwei Sun, Kun Cai, Pingli He, Gang Lin, Zengkai Qi, Hu Liu, Junshu Yan, Ning Ma   +8 more
wiley   +1 more source

Thiamine Therapy During Refractory Lactic Acidosis in Critically Ill Children

Journal of Pediatric Emergency and Intensive Care Medicine
Introduction: Thiamin deficiency, which is an overlooked but important cause of lactic acidosis, can lead to several clinical symptoms, including neuropathy, cardiogenic shock, and death, even though it can be easily treated in critically ill children ...
Fevzi Kahveci, İlker Fındık, Hasan Özen, Mert Kaan Coşkun, Hacer Uçmak, Anar Gurbanov, Burak Balaban, Merve Havan, Tanıl Kendirli   +8 more
doaj   +1 more source

The Health Consequences of Senior Hunger in the United States: Evidence from the 1999-2010 NHANES [PDF]

, 2014
Millions of seniors are food insecure in the United States, meaning that scores do not have access to enough food at all times for an active, healthy life.
Craig Gunderson, James P. Ziliak
core