Results 111 to 120 of about 37,742 (346)

Physiological Aspects of Genetics [PDF]

open access: yes, 1954
A considerable amount of evidence indicates that desoxyribonucleic acid is capable of duplicating itself, a property also possessed by genes. (By a self-duplicating material, we mean one which plays some essential role in its own production.) Watson ...
Horowitz, N. H., Owen, Ray D.
core   +1 more source

Developments in nitrous oxide capture technologies: bridging current research to clinical applications

open access: yesAnaesthesia, EarlyView.
Summary Introduction Many inhaled anaesthetic agents are greenhouse gases. Capture technologies have been developed to prevent environmental emissions of volatile agents, but no such devices exist for nitrous oxide. Further to this, the unique societal position of the use of nitrous oxide for patients in labour means it cannot readily be substituted ...
Simon Molisso   +4 more
wiley   +1 more source

Thiamin deficiency and brain disorders [PDF]

open access: yesNutrition Research Reviews, 2003
AbstractThiamin plays a key role in the maintenance of brain function. Thiamin diphosphate is cofactor for several enzymes involved in glucose metabolism whereas thiamin triphosphate has distinct properties at the neuronal membrane. Thiamin metabolism in the brain is compartmented between neurons and neighbouring glial cells.
openaire   +2 more sources

When, which and how to switch: Navigating JAK inhibitors in myelofibrosis

open access: yesBritish Journal of Haematology, EarlyView.
Navigating choice of JAK inhibitor (JAKi) therapy for patients with myelofibrosis who are JAKi‐naïve and for those who have previously been treated with a JAKi.
Jennifer O'Sullivan   +2 more
wiley   +1 more source

The Implications of Atlantic Salmon (Salmo salar L.) Fatty Acid Profiles for Their Thiamine Status

open access: yesEcology and Evolution
Thiamine deficiency is an ongoing issue across the Northern Hemisphere, causing reproductive failure in multiple salmonid populations. In the Baltic Sea, a large brackish water system in northern Europe, previous research has suggested that this ...
Vittoria Todisco   +6 more
doaj   +1 more source

Cerebral Acetylcholine in Thiamine Deficiency

open access: yesExperimental Biology and Medicine, 1970
SummaryThis study assesses the hypothesis that severe thiamine deficiency may lead to a depletion of cerebral ACh, which, in turn, may be responsible for the cerebral dysfunction seen in this condi...
K V, Speeg   +3 more
openaire   +2 more sources

PIK‐III‐Mediated Elevation of Thiamine Re‐Sensitises Renal Cell Carcinoma to Cuproptosis via Activating PDHA1

open access: yesCell Proliferation, EarlyView.
PIK‐III enhancing the efficacy of cuproptosis to kill renal cancer cells through dysregulating thiamine metabolism and dephosphorylation of pyruvate dehydrogenase complex E1 (PDHA1), providing a potential option for treatment of cuproptosis‐resistant renal cancer by the combination of PIK‐III and elesclomol.
Dongdong Xie   +8 more
wiley   +1 more source

Beriberi Induced Cardiomyopathy Requiring Salvage Venoarterial Extracorporeal Membrane Oxygenation

open access: yesCase Reports in Critical Care, 2016
Beriberi refers to a constellation of symptoms caused primarily by thiamine (vitamin B1) deficiency. An acute and fulminant presentation of this rare condition has been described in the literature as “Shoshin” beriberi which is characterized by ...
Aditya Shah   +3 more
doaj   +1 more source

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