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Susceptibility of the cerebellum to thiamine deficiency

Cerebellum, 2006
Thiamine or vitamin B(1), an essential nutrient absorbed from the diet, is involved in vital brain metabolic and cellular functions, including carbohydrate metabolism and neurotransmitter production. Diencephalic regions and, in particular, the cerebellum demonstrate lesions in cases of prolonged thiamine deficiency, such as that observed in alcohol ...
Patrick Mulholland   +1 more
exaly   +3 more sources

Thiamine diphosphatase in thiamine deficiency

Experientia, 1962
In Thiamin-Mangelkuken wurde eine erhohte Thiamin-Diphosphatase-Aktivitat festgestellt. In Figur 1 sind die Mengen an freigesetztem anorganischem Phosphat in μMol/g Gewebe/h angegeben. Die Normalwerte betragen durchschnittlich 43,0 Einheiten, wahrend das pathologische Gewebe bis zu 60 Einheiten enthalt.
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Thiamine-deficient encephalopathy in rats: Effects of deficiencies of thiamine and magnesium

Brain Research, 1986
Thiamine- and vitamin B-deficient encephalopathy was produced in adult Wistar rats and the effect of magnesium deprivation and/or the administration of guanidine, a magnesium antagonist, was studied. These encephalopathic rats had symmetrical lesions, edema, exudation of fibrin, spongy changes, petechial hemorrhages, neuronal degeneration and gliosis ...
I, Goto   +3 more
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Thiamine deficiency in cats

Veterinary Record, 2017
PETS at Home has recalled three products in its range of AVA dry cat food when, following an investigation, it confirmed that the concentration of thiamine in these products was lower than expected and too low for some cats fed solely on these diets. This issue was confined to the variants for indoor/neutered cats (1.5 kg), mature cats (2 kg and 4 kg ...
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Role of astrocytes in thiamine deficiency

Metabolic Brain Disease, 2014
Thiamine deficiency (TD) is the underlying cause of Wernicke's encephalopathy (WE), an acute neurological disorder characterized by structural damage to key periventricular structures in the brain. Increasing evidence suggests these focal histological lesions may be representative of a gliopathy in which astrocyte-related changes are a major feature of
Szeifoul, Afadlal   +2 more
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Thiamine Deficiency and Glyoxylic Acid

Annals of Nutrition and Metabolism, 1981
The effect of thiamine deficiency on glyoxylic acid metabolism in mice and rats was investigated to determine whether the vitamin deficiency results in gross effects on glyoxylate levels via an alteration in the activity of alpha-ketoglutarate:glyoxylate carboligase.
C B, Stewart, J, Grammer, R W, Brosemer
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