Results 121 to 130 of about 75,666 (233)
ABSTRACT Isobutanol is a fusel alcohol that can be produced microbially for use as a biofuel or upgraded into sustainable aviation fuel (SAF). A key enzyme in the isobutanol biosynthetic pathway is 2‐ketoacid decarboxylase (KDC), which irreversibly decarboxylates 2‐ketoisovalerate (KIV) to yield isobutyraldehyde.
Joshua J. Dietrich +6 more
wiley +1 more source
A self‐sufficient, NAD(P)H‐independent enzyme cascade for the synthesis of indigo from L‐tryptophan. The minimal cascade uses pyruvate, a byproduct of tryptophan cleavage, to generate hydrogen peroxide, which fuels the key hydroxylation of indole to indoxyl by an engineered tyrosine hydroxylase.
Vivian P. Willers +2 more
wiley +1 more source
Role of tautomerism in RNA biochemistry [PDF]
Heterocyclic nucleic acid bases and their analogs can adopt multiple tautomeric forms due to the presence of multiple solvent-exchangeable protons.
Essigmann, John M. +2 more
core +1 more source
Small Molecule‐Based Conditional Gene Regulation: Advances and Applications
The precise, temporal, and reversible control of gene expression using small molecule ligands is crucial for understanding complex cellular functions and is rapidly advancing the field of synthetic biology. Small molecule‐mediated conditional gene regulation has widespread applications, including bio‐manufacturing, cellular reprogramming, gene therapy,
Mohd Afaque Ansari +3 more
wiley +1 more source
The wide phenotypic spectrum of thiamine metabolism dysfunction syndrome 5 and its treatment
Thiamine metabolism dysfunction syndrome 5 (TMDS5) is a rare inborn error of metabolism caused by variants in TPK1, leading to reduced TPK levels. This enzyme is crucial for the production of thiamine pyrophosphate, the active form of thiamine, a vital ...
Alice Dallan +8 more
doaj +1 more source
Nutritional deficiencies in homeless persons with problematic drinking:A systematic review [PDF]
BACKGROUND: A significant proportion of homeless people drink alcohol excessively and this can lead to malnutrition and consequent medical problems.
Bonner, Adrian +7 more
core +3 more sources
Metabolism consists of biochemical reactions that are combined to generate a robust metabolic network that can respond to perturbations and also adapt to changing environmental conditions.
Jannell V. Bazurto +2 more
doaj +1 more source
BCKDH: the missing link in apicomplexan mitochondrial metabolism is required for full virulence of Toxoplasma gondii and Plasmodium berghei [PDF]
While the apicomplexan parasites Plasmodium falciparum and Toxoplasma gondii are thought to primarily depend on glycolysis for ATP synthesis, recent studies have shown that they can fully catabolize glucose in a canonical TCA cycle.
Barrett, Michael P. +11 more
core +1 more source
The objectives of the review are the collection, concise description and evaluation of the various chromatographic techniques used for the separation and quantitative determination of macro- and microcomponents present in ...
Cserháti, Tibor, Szőgyi, Mária
core
Thiamine deficiency in the western diet and dementia risk [PDF]
This article has been accepted for publication in British Journal of Nutrition. The version of record, Richard Hoffman, ‘Thiamine deficiency in the Western diet and dementia risk’, British Journal of Nutrition, Vol 116(1): 188-189, first published online
Richard Hoffman, Velísek
core +1 more source

