Results 181 to 190 of about 75,666 (233)

Molecular level insights into the inhibition of gene expression by thiamine pyrophosphate (TPP) analogs for TPP riboswitch: A well-tempered metadynamics simulations study.

Journal of Molecular Graphics and Modelling, 2021
Riboswitches are metabolite sensing aptamer domains present in non-coding regions in RNA and act as gene-regulating elements. Thiamine pyrophosphate (TPP) riboswitch is evolved as a new target for developing antibiotics against many pathogenic bacteria ...
Padmaja D. Wakchaure, B. Ganguly
semanticscholar   +1 more source

The effect of thiamine pyrophosphate on ethambutol-induced ocular toxicity

Cutaneous and Ocular Toxicology, 2016
Nihal Cetin, Durdu Altuner, Hamît Håkan   +2 more
exaly   +2 more sources

Conformational Transition and Recognition Mechanism of Eukaryotic Riboswitches Powered by Thiamine Pyrophosphate Analogues: An Elucidation through Multiple Short Molecular Dynamics Simulations and Markov Model.

Journal of Physical Chemistry B
Understanding the ligand-mediated conformational changes in eukaryotic riboswitches is crucial for elucidating their functional roles. In this study, multiple short molecular dynamics simulations, followed by Markov model analysis, were conducted to ...
Jianzhong Chen, Jian Wang, Wei Wang, Wanchun Yang, Lu Zhao, Jing Su   +5 more
semanticscholar   +1 more source

Effects of thiamine and thiamine pyrophosphate on epileptic episode model established with caffeine in rats

Epilepsy Research, 2014
Mehmet Ibrahim Turan, Huseyin Tan, Nihal Cetin   +2 more
exaly   +2 more sources

Thiamine pyrophosphate riboswitches in Bacteroides species regulate transcription or translation of thiamine transport and biosynthesis genes

bioRxiv, 2019
Thiamine (vitamin B1) and its phosphorylated precursors are necessary for decarboxylation reactions required in carbohydrate and branched chain amino acid metabolism.
Zachary A. Costliow, P. Degnan, Carin K. Vanderpool   +2 more
semanticscholar   +1 more source

A comparative investigation of biochemical and histopathological effects of thiamine and thiamine pyrophosphate on ischemia–reperfusion induced oxidative damage in rat ovarian tissue

Archives of Pharmacal Research, 2013
Ebru Sener, Nihal Cetin, Durdu Altuner   +2 more
exaly   +2 more sources

Ca2+-dependent inhibition of branched-chain α-ketoacid dehydrogenase kinase by thiamine pyrophosphate.

Biochemical and Biophysical Research Communications - BBRC, 2018
Catabolism of the branched-chain amino acids (BCAAs: leucine, isoleucine, and valine) is regulated by the branched-chain α-ketoacid dehydrogenase (BCKDH) complex, which in turn is regulated by phosphorylation catalyzed by BCKDH kinase (BDK).
S. Noguchi, Yusuke Kondo, Rina Ito, T. Katayama, S. Kazama, Y. Kadota, Y. Kitaura, Robert A. Harris, Y. Shimomura   +8 more
semanticscholar   +1 more source

Transport of platinum bonded nucleotides into proteoliposomes, mediated by Drosophila melanogaster thiamine pyrophosphate carrier protein (DmTpc1)

Journal of Inorganic Biochemistry, 2014
Chiara Carrisi, Daniela Antonucci, Paola Lunetti   +2 more
exaly   +2 more sources

Fabricating of flame retardant and antibacterial lyocell fabric based on thiamine pyrophosphate modification

Cellulose, 2023
Xiao-wei Su, Wei Tan, Xiaohui Liu, Yuanlin Ren, Ying Sun   +4 more
semanticscholar   +1 more source

The mechanism of reactions catalyzed by thiamine pyrophosphate

Experientia, 1956
Es wird ein Mechanismus fur verschiedene enzymatische Reaktionen, bei denen Thiaminpyrophosphat als Coferment wirkt, vorgeschlagen.
K. Wiesner, Z. Valenta
openaire   +1 more source