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Synthesis of 4H-thiazines

Chemistry of Heterocyclic Compounds, 2016
Thiazines represent an important class of heterocyclic compounds due to their valuable biological properties. For example, some derivatives of thiazine are cannabinoid receptor agonists, also they can act as an antihypotensive, antitubercular, and antibacterial agents.
Aurelija Urbanaitė, Inga Čikotienė
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Metal Contaminants in Commercial Thiazine Dyes

Stain Technology, 1975
The iron, potassium, sodium and zinc content of commercial samples of the thiazine dyes azure A (C.I. 52005), azure B (C.I. 52010), azure C (C.I. 52002), methylene blue (C.I. 52015), new methylene blue (C.I. 52030), polychrome methylene blue, thionine (C.I. 52000) and toluidine blue (C.I.
P N, Marshall, S M, Lewis
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Photo-Sensitivity of Thiazine Leucobases

Nature, 1961
DURING the course of experiments designed to investigate the staining of nucleic acid in histological sections, I happened to gather together on one bench a number of solutions of basic dyes reduced to their colourless sulphite leucobase. These included methyl green, basic fuchsin and a series of thiazines, namely, thionin, azure A, B and C, and ...
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ChemInform Abstract: 4H‐1,4‐Thiazines and 2H‐1,4‐Thiazines from 2‐(Dialkylhydrazono) thioacetophenones.

ChemInform, 1993
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
A. RELIQUET   +3 more
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N,N-DIALKYLAMINOALKYL SUBSTITUTED QUINOBENZO[1,4]THIAZINES AND DIQUINO[1,4]THIAZINES#

Phosphorus, Sulfur, and Silicon and the Related Elements, 2000
Abstract 12-(N,N-Dialkylaminoalkyl)quino[1,4]benzothiazines 2c-2g were obtained by alkylation of 12H-quino[1,4]benzothiazines 2a and 2b with N,N-dialkylaminoalkyl chlorides in dioxane. 14H-Diquino [1,4]thiazine 4a was unreactive in the same conditions.
K. Pluta, A. Maślankiewicz, M. Szmielew
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4H-1,4-THIAZINES ET 2H-1,4-THIAZINES A PARTIR DE 2-(DIALKYLHYDRAZONO)-THIOACETOPHENONES

Phosphorus, Sulfur, and Silicon and the Related Elements, 1992
Abstract 2-(Dialkylhydrazono)thioacetophenones 1 react with N-phenylmaleimide and lead via [4 + 2] cycloaddition to 4-amino-3,4-dihydro-2H-1,4-thiazines 2 which are easily converted into 4H-1,4-thiazines 3. Reaction with 1,4-naphthoquinone leads directly to 4H-1,4-thiazines 4.
A. Reliquet   +3 more
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Quinoxalino[2,3-b]-1,4-thiazines

Chemistry of Heterocyclic Compounds, 1971
Quinoxalino[2,3-b]-1,4-thiazines were obtained by the reaction of 2-aminoquinoxaline-3-thione and its 6,7-dimethyl derivative with α-halocarbonyl compounds. Hydrolysis of these compounds in alkaline and acid media gave 2-amino-3-quinoxalone and quinoxaline-2,3-dione. The IR and UV spectra are presented.
I. Ya. Postovskii, N. G. Koshel'
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Dielectric properties of thiazine derivatives

Electrochimica Acta, 1968
Abstract The thiazine derivatives promethazine, chlorpromazine, trimeprazine, prochlorperazine, trifluoperazine, methotrimeprazine and thioproperazine exhibit similar dielectric behaviour, and all except the last two are subject to severe supercooling.
F. Gutmann, H. Keyzer
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Dithieno‐1,4‐thiazines. Part I

Recueil des Travaux Chimiques des Pays-Bas, 1970
AbstractThe synthesis of the first dithieno[2,3‐b : 2′,3′‐e]‐1,4‐thiazine is described, this compound was prepared by condensation of 3‐thiophenethiol with methyl 2‐bromo‐3‐nitrothiophene‐5‐carboxylate followed by reduction, acylation, bromination with NBS and ringclosure with Cu, K2CO3 in nitrobenzene.A thieno‐1,4‐benzothiazine was prepared in the ...
C. J. Grol, J. S. Faber
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Luminescence of Leuco-Thiazine Dyes

Journal of Fluorescence, 2003
Details of the novel luminescence of the leuco forms of the thiazine dyes, methylene blue and thionine, are reported, including their emission maxima, quantum yields and lifetimes of the luminescence. Other work shows that this luminescence is independent of reducing agent type and solution pH and is a common feature of most thiazine dyes.
Lee, S.K., Mills, Andrew
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