Design and synthesis of biotin- or alkyne-conjugated photoaffinity probes for studying the target molecules of PD 404182. [PDF]
To investigate the mechanism of action of the potent antiviral compound PD 404182, three novel photoaffinity probes equipped with a biotin or alkyne indicator were designed and synthesized based on previous structure-activity relationship studies.
Fujii, Nobutaka +5 more
core +1 more source
A carbon‐supported quartzite powder waste composite was evaluated as a sustainable and low‐cost adsorbent for the removal of the cationic dye Methylene Blue (MB) and the anionic dye Reactive Black 5 (RB5). The valorization of quartzite waste as a silica source represents an environmentally attractive strategy to mitigate disposal impacts while enabling
Lucas Destefani Paquini +7 more
wiley +1 more source
6-Bromo-1-methyl-4-[2-(4-methylbenzylidene)hydrazinylidene]-3H-2λ6,1-benzothiazine-2,2-dione
In the title compound, C17H16BrN3O2S, the two fused rings are twisted by a dihedral angle of 6.61 (15)°. The thiazine ring adopts a sofa conformation.
Muhammad Shafiq +4 more
doaj +1 more source
Davis-Beirut reaction: route to thiazolo-, thiazino-, and thiazepino-2H-indazoles. [PDF]
Methods for the construction of thiazolo-, thiazino-, and thiazepino-2H-indazoles from o-nitrobenzaldehydes or o-nitrobenzyl bromides and S-trityl-protected 1°-aminothioalkanes are reported.
Farber, Kelli M +2 more
core +2 more sources
OPN‐Derived Peptides Generated by Proteasomes Can Promote Cell Migration via CD44 Activation
Osteopontin (OPN) is a pleiotropic cytokine that is overexpressed in many autoimmune diseases and solid cancers. Here we show that the 20S proteasome can degrade, in vitro, both the full‐length OPN and the OPN‐C fragment generated in the extracellular space and produce both canonical and spliced peptides.
Hindh Imad +13 more
wiley +1 more source
Crystal structure of (E)-2-cyano-3-(12-methyl-12H-benzo[b]phenothiazin-11-yl)acrylic acid
In the title compound, C21H14N2O2S, a donor–acceptor type of benzo[b]phenothiazine (bpz) derivative, the thiazine ring adopts a boat conformation and the bond-angle sum at the N atom is 360.0°.
Motonori Watanabe, Tatsumi Ishihara
doaj +1 more source
Synthesis of Pyrrolidine-Fused 1,3-Dithiolane Oligomers by the Cycloaddition of Polycyclic Dithiolethiones to Maleimides and Evaluation as Mercury(II) Indicators [PDF]
The scandium triflate-catalyzed cycloaddition reaction of polycyclic 1,2-dithiolethiones to maleimides is described. The reaction constitutes an easy approach to linear as well as branched oligomeric cis-fused dihydro[1,3]dithiolo[4,5-c]pyrrole-4,6 ...
Cuevas Vicario, José Vicente +6 more
core +1 more source
Although this article formally presents a regioselective photochemical ring enlargement of thietanes into 1,2‐ or 1,3‐dithianes, time‐dependent density functional theory calculations have revealed that 1,3‐dithianes are in fact formed thought photoinduced hydrogen atom transfers from 1,2‐dithianes initially resulting from the ring enlargement using ...
Gabriel Cormier +5 more
wiley +1 more source
2-[1,1-Dioxo-2-(2,4,5-trifluorobenzyl)-2H-1,2-benzothiazin-4-yl]acetic acid
In the title compound, C17H12F3NO4S, the heterocyclic thiazine ring adopts a half-chair conformation with the S and the N atoms displaced by −0.608 (3) and 0.105 (3) Å, respectively, from the mean plane ...
Changjin Zhu, Yanchun Yang, Youzhu Yu
doaj +1 more source
Practical tests with anthelmintics for grazing lambs [PDF]
The bulletin is a report on University of Missouri Agricultural Experiment Station research project 142, 'Sheep Production'--P. [3].Digitized 2007 AES.Includes bibliographical references (page 16)
Ross, C. V., 1914- +1 more
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