Results 51 to 60 of about 2,614 (189)

OPN‐Derived Peptides Generated by Proteasomes Can Promote Cell Migration via CD44 Activation

Journal of Immunology Research, Volume 2026, Issue 1, 2026.
Osteopontin (OPN) is a pleiotropic cytokine that is overexpressed in many autoimmune diseases and solid cancers. Here we show that the 20S proteasome can degrade, in vitro, both the full‐length OPN and the OPN‐C fragment generated in the extracellular space and produce both canonical and spliced peptides.
Hindh Imad, Kathryn E. Strange, Chiara Dianzani, Wai Tuck Soh, Sophie Siddons, Shahram Kordasti, Casimiro Luca Gigliotti, Annalisa Chiocchetti, Henning Urlaub, Timothy James Nott, Umberto Dianzani, Juliane Liepe, Michele Mishto, Poorani Gurumallesh Prabu   +13 more
wiley   +1 more source

Visible‐Light Photocatalyzed Selective Synthesis of 1,2‐ or 1,3‐Dithianes From Thietanes: An Experimental and Theoretical Study

Advanced Synthesis &Catalysis, Volume 367, Issue 24, December 22, 2025.
Although this article formally presents a regioselective photochemical ring enlargement of thietanes into 1,2‐ or 1,3‐dithianes, time‐dependent density functional theory calculations have revealed that 1,3‐dithianes are in fact formed thought photoinduced hydrogen atom transfers from 1,2‐dithianes initially resulting from the ring enlargement using ...
Gabriel Cormier, Manuel Pedrón, Maria I. Lapuh, Regis Guillot, Ilaria Ciofini, Thomas Boddaert   +5 more
wiley   +1 more source

Design, evaluation, cytotoxic activity, molecular docking, ADMET analysis, and dynamic simulations and the preparation of new isoxazoles, thiazoles, 1,3-thiazines, and thiazolopyrimidines derived from quinoline-pyridopyrimidines

Pharmaceutical Biology
Context Quinoline, isoxazole, and pyridothiazolopyrimidinone derivatives are novel compounds with significant biological activity, exhibiting anticancer properties and holding promising therapeutic applications.Objective This investigation synthesized ...
Ameen A. Abu-Hashem, Nasser Amri, Ahmed F. El-Sayed   +2 more
doaj   +1 more source

A Miniaturized Optical Bioassay Towards Early‐Stage Diagnosis of Cancer Using Immunosensing of Biomarkers (CA 15.3, PSA and CEA) by Toluidine Blue‐Decorated Poly(Methyl Methacrylate): Proof of Concept

Analytical Science Advances, Volume 6, Issue 2, December 2025.
ABSTRACT The current study evaluated the application of a novel and advanced photochemical biosensing platform for the detection of multiple biomarkers of prostate‐specific antigen (PSA), carcinoembryonic antigen (CEA) and cancer antigen 15–3 (CA 15.3) in human plasma samples using optical biomedical analysis.
Seyyed Mohammad Yaghoubi, Hamed Bahari, Mohammad Hasanzadeh, Nasrin Shadjou   +3 more
wiley   +1 more source

Organic field‐effect transistors: Materials design, device physics, and contact engineering for high‐performance flexible electronics

Information &Functional Materials, Volume 2, Issue 4, Page 267-305, December 2025.
This review bridges molecular design with device engineering to address key challenges in organic transistors. By integrating materials chemistry with contact optimization, it provides pathways toward stable, high‐performance flexible electronics. Abstract Organic field‐effect transistors are widely recognized as key enabling components for low‐cost ...
Fenglan Kuang, Fei Wang, Dawei Duan, Yicong Ma, Xiaokang Sun, Soumitra Satapathi, Annie Ng, Haoran Lin, Zheng Li, Yufei Zhong, Hanlin Hu   +10 more
wiley   +1 more source

The Photophysical Properties Investigation of Hybrid Associates of Methylene Blue Molecules with Colloidal CdS Quantum Dots and CdS / Cd(OH)2 "Core-Shell" Systems [PDF]

, 2013
The spectral properties of associates of methylene blue molecules with colloidal CdS quantum dots and CdS / Cd(OH)2 «core-shell» systems were investigated.
Khoklov, V.Yu., Latyshev, A.N., Ovchinnikov, O.V., Shapiro, B.I., Shatskikh, T.S., Smirnov, M.S.   +5 more
core  

Synthesis, Characterize and Evaluation of anti-bacterial and anti-fungal activity of thiazines [PDF]

, 2019
1,3 – Thiazines have been applied as useful starting materials in the stereo selective synthesis of compounds of pharmacological interest and they have served as chiral ligants and auxiliaries in enantioselective transformation.
Salman, B. Syed, sarmad, Arsalan, Sultana, Razia   +2 more
core   +2 more sources

High‐Throughput Photocatalysis for Generating Reliable Datasets Analyzed by Machine Learning

ChemPhysChem, Volume 26, Issue 23, November 28, 2025.
Photocatalytic materials are typically tested on limited analytes, limiting real‐world relevance. High throughput‐photocatalysis, enabling rapid, modular experimentation across 27 analytes is introduced. Using P25 TiO2, dye removal datasets with machine learning is paired.
Mark Croxall, Reece Lawrence, Jiaqi Gong, M. Cynthia Goh   +3 more
wiley   +1 more source

Synthesis and reactions of aminopropenes, which contains functional groups [PDF]

, 2013
В рамках данной работы осуществлен синтез енаминов, содержащих остатки первичных, вторичных, третичных аминов, а также амидную и тиоамидную группы. Проведено комплексное исследование структуры полученных соединений с помощью спектральных методов, включая
Lugovik, K. I., Луговик, К. И.
core  

Evaluation of Substituted 1,2,3-Dithiazoles as Inhibitors of the Feline Immunodeficiency Virus (FIV) Nucleocapsid Protein via a Proposed Zinc Ejection Mechanism [PDF]

, 2016
A diverse library of 5-thieno-, 5-oxo-, and 5-imino-1,2,3-dithiazole derivatives was synthesized and evaluated for efficacy against the feline immunodeficiency virus (FIV) as a model for HIV in cells.
Amodeo, Appel, Asquith, Asquith, Augustine, Besson, Bisset, Bourbigot, Carteau, Charalambous, Cook, Cottenceau, Crandell, Darlix, Demene, Elder, Garg, Gorelick, Hatziioannou, Kim, Klein, Konstantinova, Konstantinova, Konstantinova, Konstantinova, Koutentis, Leslie, Loo, Manrique, Matsui, Mayasundari, Mirambeau, Morellet, Mori, Oppedisano, Pannecouque, Pauling, Pedersen, Popov, Ramboarina, Remy, Rice, Rice, Rice, Rong, Sancineto, Summa, Sylvester, Tanchou, Thiéry, Turpin, Vercruysse, Wani, Wolfe, Woodcock, Woodcock, Yamamoto, Zhang   +57 more
core   +1 more source