ChemistryOpen, Volume 14, Issue 11, November 2025.StreptomeDB‐derived nitro compounds are screened against Mycobacterium tuberculosis decaprenylphosphoryl‐D‐riboseoxidase (DprE1) . Covalent docking, molecular dynamics simulations, and molecularmechanics/generalized Born surface area analyses identify hydroxythaxtomin and lajollamycin B as potent DprE1 inhibitors, surpassing the reference PBTZ169 in ...
Doaa G. M. Mahmoud +4 more
wiley +1 more source
Small Molecular Dibenzochalcogenophenes as Potent Organic Emitters
Chemistry – A European Journal, Volume 31, Issue 56, October 8, 2025.This review compiles recent achievements and applications of purely organic small luminescent DBC. We present frequently employed functionalities and design strategies, accomplishing room temperature phosphorescence (RTP). In addition, we discuss the challenges for luminescent selenium and tellurium derivatives as well as the influence of commercial ...
Marco Schmiedtchen +3 more
wiley +1 more source
, 2009 International audienceA new one-pot domino reaction for a general entry to functionalised bridged bicyclo[n.2.1] ring systems from α,α'-diactivated cyclic ketones and trans-1,4-dihalides is described.
Bensa, David +4 more
core +4 more sources
Illuminating Tau Aggregates: Multiscale Approaches for Detection, Imaging, and Understanding
Aggregate, Volume 6, Issue 10, October 2025.This review presents recent advances in molecular imaging of tauopathies, focusing on tau aggregation mechanisms, structural polymorphism, and imaging strategies. It highlights the development of tau‐selective fluorescent probes and PET tracers and explores emerging techniques such as cryo‐EM and super‐resolution imaging, offering a multiscale ...
Kaustubh R. Bhuskute +2 more
wiley +1 more source
Addition and cycloaddition reactions of Phosphinyl- and Phosphonyl-2H-Azirines, Nitrosoalkenes and Azoalkenes [PDF]
, 2012 An overview of the use of 2H-azirines, conjugated nitrosoalkenes and conjugated azoalkenes bearing phosphorus substituents in addition and cycloaddition reactions is presented, focused on strategies for the synthesis of aminophosphonate and ...
Lemos, A.
core
Benzothiazole durch C-C-Spaltung von alpha-[(2-Nitrophenyl)thio]ketonen [PDF]
, 1984 Einwirkung von Ammoniak bzw. Natronlauge auf die -[(2-Nitrophenyl)thio]ketone 4, 11a-c und 16 führt unter CC-Spaltung zu den Benzothiazol-N-oxid-Derivaten 8, 12ac und 17; aus dem 3-[(2-Nitrophenyl)thio]-4-piperidon-Derivat 22 entsteht der 2 ...
Babichev +10 more
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Reaction of 1,2-Diaza-1,3-butadienes with thiol derivates: a versatile construction of nitrogen/sulfur containing heterocycles [PDF]
, 2015 none9sìopenATTANASI O.A.; FILIPPONE P; LILLINI S; NICOLINI S; MANTELLINI F; APARICIO D; IGNACIO R; DE LOS SANTOS J.M; PALACIOS FAttanasi, ORAZIO ANTONIO; Filippone, Paolino; Lillini, S; Nicolini, Simona; Mantellini, Fabio; Aparicio, D; Ignacio, R; DE LOS
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Tautomeric Equilibria Studies by Mass Spectrometry [PDF]
, 2008 Tautomerism in organic chemistry has been extensively studied in condensed phase by spectrometric methods, mainly by IR and NMR techniques. Mass spectrometry studies start 40 years ago but just recently it has been recognized the importance of the mass ...
Eduardo A. Castro +3 more
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Verapamil-Sensitive Transport of Quinacrine and Methylene Blue via the Plasmodium falciparum Chloroquine Resistance Transporter Reduces the Parasite's Susceptibility to these Tricyclic Drugs. [PDF]
, 2015 BACKGROUND: It is becoming increasingly apparent that certain mutations in the Plasmodium falciparum chloroquine resistance transporter (PfCRT) alter the parasite's susceptibility to diverse compounds. Here we investigated the interaction of PfCRT with 3
Lehane, Adele M +6 more
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Synthesis and biological activities of some 3,5-diaryl-N-hydroxy-tetrahydro-1,4-thiazine-1,1-dioxides [PDF]
, 2016 Some new 3,5-diaryl-N-hydroxy-tetrahydro-1,4-thiazine-1,1-dioxides (6a-i) have been synthesized by reacting thiazine (4) with dimethyldioxirane (5) and tested for their antibacterial and acute toxicity studies.
Thangamani, A.
core +2 more sources