Results 1 to 10 of about 2,743 (163)

Pro-Apoptotic and Anti-Migration Properties of a Thiazoline-Containing Platinum(II) Complex in MDA-MB-231 Breast Cancer Cells: The Role of Melatonin as a Synergistic Agent

Antioxidants, 2022
Triple-negative breast cancer (TNBC) is an aggressive cancer insensitive to hormonal and human epidermal growth factor receptor 2 (HER2)-targeted therapies and has a poor prognosis.
Samuel Estirado, Elena Fernández-Delgado, Emilio Viñuelas-Zahínos, Francisco Luna-Giles, Ana B. Rodríguez, José A. Pariente, Javier Espino   +6 more
doaj   +1 more source

Neuroprotective effects of the antioxidant action of 2-cyclopropylimino-3-methyl-1,3-thiazoline hydrochloride against ischemic neuronal damage in the brain [PDF]

BMB Reports, 2013
Ischemia is characterized by oxidative stress and changes in theantioxidant defense system. Our recent in vitro study showedthat 2-cyclopropylimino-3-methyl-1,3-thiazoline hydrochlorideprotects cortical astrocytes against oxidative stress.
Soo Young Choi, Duk-Soo Kim, Eun-A Kim, A Reum Han, Dae Won Kim, Seung Cheol Ha, Sung-Woo Cho   +6 more
doaj   +1 more source

Comparison of Odorants in Beef and Chicken Broth—Focus on Thiazoles and Thiazolines

Molecules, 2022
The shift in consumer landscape towards vegan, vegetarian and flexitarian diets has created an unprecedented challenge in creating meat aroma from plant-based alternatives.
Huiqi Yeo, Dimitrios P. Balagiannis, Jean H. Koek, Jane K. Parker   +3 more
doaj   +1 more source

Bioactivity of Novel Pyrazole-Thiazolines Scaffolds against Trypanosoma cruzi: Computational Approaches and 3D Spheroid Model on Drug Discovery for Chagas Disease

Pharmaceutics, 2022
Chagas disease, a century-old disease that mainly affects the impoverished population in Latin America, causes high morbidity and mortality in endemic countries.
Leonardo da Silva Lara, Guilherme Curty Lechuga, Lorraine Martins Rocha Orlando, Byanca Silva Ferreira, Bernardo Araújo Souto, Maurício Silva dos Santos, Mirian Claudia de Souza Pereira   +6 more
doaj   +1 more source

Trichloroisocyanuric acid as an efficient homogeneous catalyst for the chemoselective synthesis of 2-substituted oxazolines, imidazolines and thiazolines under solvent-free condition [PDF]

Journal of the Serbian Chemical Society, 2012
Trichloroisocyanuric acid as a commercially available and inexpensive catalyst has been used in a new, facile and efficient procedure for the synthesis of 2-oxazolines, 2-imidazolines and 2-thiazolines through the reaction of nitriles with 2 ...
Hojati Fatemeh Seyedeh, Nezhadhoseiny Atefe Seyede   +1 more
doaj   +1 more source

Synthesis, Structure and Molecular Docking of New 4,5-Dihydrothiazole Derivatives Based on 3,5-Dimethylpyrazole and Cytisine and Salsoline Alkaloids

Molecules, 2022
The interaction results of 1,2-dibromo-3-isothiocyanatopropane with some pyrazoles as well as cytisine and salsoline alkaloids were presented in this paper.
Marat K. Ibrayev, Oralgazy A. Nurkenov, Zhanar B. Rakhimberlinova, Altynaray T. Takibayeva, Irina V. Palamarchuk, Dastan M. Turdybekov, Assel A. Kelmyalene, Ivan V. Kulakov   +7 more
doaj   +1 more source

مطالعه شیمی کوانتومی برهم کنش نانوذرات پلیمری PLGA به عنوان حامل دارویی با عاملهای ضدسرطانی تیازولین [PDF]

International Journal of New Chemistry, 2019
Thiazoles derivatives are consisted in chemical compounds such as antimicrobial and anticancer medicine. Since polylactic-co-glycolic acid (PLGA) polymeric nanoparticles has been conversed about nanomedicine applications and particularly as drug delivery
Nosrat Madadi Mahani
doaj   +1 more source

Inhibition of GlcNAc-Processing Glycosidases by C-6-Azido-NAG-Thiazoline and Its Derivatives

Molecules, 2014
NAG-thiazoline is a strong competitive inhibitor of GH20 β-N-acetyl- hexosaminidases and GH84 β-N-acetylglucosaminidases. Here, we focused on the design, synthesis and inhibition potency of a series of new derivatives of NAG-thiazoline modified at the C ...
Jana Krejzová, Petr Šimon, Lubica Kalachova, Natallia Kulik, Pavla Bojarová, Petr Marhol, Helena Pelantová, Josef Cvačka, Rüdiger Ettrich, Kristýna Slámová, Vladimír Křen   +10 more
doaj   +1 more source

Flavouring Group Evaluation 21 Revision 6 (FGE.21Rev6): thiazoles, thiophenes, thiazoline and thienyl derivatives from chemical groups 29 and 30

EFSA Journal, 2023
The Panel on Food additives and Flavourings (FAF) was requested to evaluate the flavouring substances 2,4‐dimethyl‐3‐thiazoline [FL‐no: 15.060] and 2‐isobutyl‐3‐thiazoline [FL‐no: 15.119] in Flavouring Group Evaluation 21 revision 6 (FGE.21Rev6).
EFSA Panel on Food Additives and Flavourings (FAF), Maged Younes, Gabriele Aquilina, Laurence Castle, Gisela Degen, Karl‐Heinz Engel, Paul J Fowler, Maria Jose Frutos Fernandez, Peter Fürst, Ursula Gundert‐Remy, Rainer Gürtler, Trine Husøy, Melania Manco, Sabina Passamonti, Peter Moldeus, Romina Shah, Ine Waalkens‐Berendsen, Matthew Wright, Romualdo Benigni, Claudia Bolognesi, Kevin Chipman, Eugenia Cordelli, Karin Nørby, Camilla Svendsen, Maria Carfì, Wim Mennes   +25 more
doaj   +1 more source

Synthesis, X-ray Analysis, Biological Evaluation and Molecular Docking Study of New Thiazoline Derivatives

Molecules, 2019
A series of new thiazoline derivatives were synthesized. Structure analyses were accomplished employing 1H-NMR, 13C-NMR, X-ray and MS techniques.
Yahia N. Mabkhot, H. Algarni, Abdulrhman Alsayari, Abdullatif Bin Muhsinah, Nabila A. Kheder, Zainab M. Almarhoon, Faiz A. Al-aizari   +6 more
doaj   +1 more source