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Synthesis and evaluation of steroidal thiazoline conjugates as potential antiviral agents.

Future Medicinal Chemistry, 2018
AIM Many heterocyclic compounds derived from natural steroids exhibited broad activities, so this work focused on the investigations on a series of steroidal thiazoline conjugates as antiviral agents.
Shaoyong Ke   +12 more
semanticscholar   +1 more source

Oligo‐(thiazolin)‐Naturstoffsynthese

Nachrichten aus Chemie, Technik und Laboratorium, 1995
Abstract“Synthese im Blickpunkt” will zur Beschäftigung mit neuen synthetischen Verfahren oder besonders eleganten und wichtigen Synthesen aus der aktuellen chemischen Literatur anregen ‐ ohne Anspruch auf Vollständigkeit. Die Rubrik erscheint alle zwei Monate und wird 1995 von Dr. Ulrich Koert, Universität Marburg, betreut.
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2‐Amino‐2‐thiazoline. V. phenylthioureido and phenylureido derivatives of 2‐thiazoline

Journal of Heterocyclic Chemistry, 1968
AbstractThe reaction of 2‐amino‐2‐thiazoline (I) with phenylisothiocyanate has been reported to give 2‐imino‐3‐phenylthiocarbamoylthiazolidine (II) at low temperatures and l‐phenyl‐3‐(2‐thiazolin‐2‐yl)‐2‐thiourea (III) at ca. 100°. When performed by us, however, this reaction gave only a single mono‐adduct regardless of the temperature.
Daniel L. Klayman   +2 more
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Synthesis of thiazolines and thiazolidines

Chemistry of Heterocyclic Compounds, 1972
Primary α-ethynylamines form thiazolines with isothiocyanates, while secondary α-ethynylamines give thiazolidines. Data on the IR, PMR, and UV spectra of the compounds obtained are presented.
I. N. Azerbaev   +3 more
openaire   +1 more source

2-Methyl-2-thiazoline

2001
[2346-00-1] C4H7NS (MW 101.19) InChI = 1S/C4H7NS/c1-4-5-2-3-6-4/h2-3H2,1H3 InChIKey = JUIQOABNSLTJSW-UHFFFAOYSA-N (lithiation produces an acetaldehyde enolate equivalent for synthesis of mono-, di-, and trisubstituted acetaldehydes,1, 2 β-hydroxy aldehydes,3 homoallylic alcohols,3 and α,α-disubstituted β-ethylenic methyl ...
Todd D. Nelson, Albert I. Meyers
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Novel synthesis of 2-thiazolines

Tetrahedron Letters, 2000
Abstract The synthesis of a series of 2-thiazolines was carried out under mild conditions from the corresponding thiazolidines, by a Ru-catalyzed/TBHP oxidation reaction conditions. The reaction was chemoselective towards the amine-imine oxidation and was also regioselective, affording the unsaturation at the 2-position of the heterocycle, even with ...
Xavier Fernandez   +2 more
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Some Conversions of Thiazoline Carboxylic Acid Esters.

ChemInform, 2003
We have carried out solvolysis of the previously described ethyl esters of 3-methyl(aryl)-4-methyl-2-thioxothiazoline-5-carboxylic acids, leading to the corresponding acids without breaking down the heterocycle. We synthesized a series of novel esters from the latter by treatment with dimethyl sulfate or reactive halides.
V. V. Dovlatyan   +3 more
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Δ-2 thiazoline et alkyl-2 Δ-2 thiazolines: etude vibrationnelle infrarouge et Raman.conformation

Journal of Molecular Structure, 1978
Resume Les spectres Raman (etat liquide) et les spectres infrarouges de la Δ-2 thiazoline et des derives alkyles en position 2 (etats vapeur, liquide, dissous et solide) ont ete examines entre 4000 et 200 cm −1 . L'attribution proposee pour les vibrations fondamentales de ces heterocycles est compatible avec une conformation plane ou tres peu ...
G. Mille, J.L. Meyer, J. Chouteau
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2-Arylimino-3-thiazolines - formation of unusual tautomers of 2-arylamino-thiazolines - a revision

Tetrahedron Letters, 1985
Abstract In contrast to previously reported results the products formed in the reaction of arylthioureas with 3-bromomethyl-2-cyanocinnamonitrile are not 2-arylimino- 3-thiazolines but 2-arylamino-4-dicyanomethyl-2-thiazolines.
Jürgen Liebscher   +2 more
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Dehydrobromierung von ?-Bromacetophenon-(2-thiazolin-2-yl)-hydrazon � HBr zu 3,6-Diphenyl-1-(2-thiazolin-2-yl)-6(2-thiazolin-2-ylazo)-1,4,5,6-tetrahydropyridazin

Monatshefte f�r Chemie, 1976
The attempted synthesis of 6,7-dihydro-3-phenyl-4H-thiazolo[2,3−c][1,2,4]-triazine (2) from5 · HBr failed and the title reaction is observed instead.
K. H. Ongania, J. Schantl
openaire   +1 more source

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