Results 51 to 60 of about 2,743 (163)

Synthesis, Anticancer Evaluation, and Molecular Docking of Novel Thiazolobenzimidazole–Thiazole Hybrids as Potent Colon Cancer Inhibitors

ChemistryOpen, Volume 14, Issue 11, November 2025.
Novel benzimidazothiazole–thiazole hybrids are synthesized and evaluated for anticancer activity against HCT‐116 colon cancer cells. Compound 16b shows superior cytotoxicity over doxorubicin. Molecular docking confirms strong binding to 6MTU protein, and ADMET profiling indicates favorable pharmacokinetics and low toxicity.
Bader Huwaimel, Amr S. Abouzied, Magdi E. A. Zaki, Abdulwahab Alamri, Basant Farag, Saad Alqarni, Sobhi M. Gomha   +6 more
wiley   +1 more source

Asymmetric Strategies for the Synthesis of Enantiopure α‐/β‐/γ‐Thio‐Carboxylic Acids Bearing a Stereocentre at CS Bond

Advanced Synthesis &Catalysis, Volume 367, Issue 18, September 29, 2025.
Enantioenriched α‐/β‐/γ‐thiocarboxylic acids featuring C–S chirality are valuable targets in organic synthesis. This review outlines recent progress in their asymmetric synthesis, including chiral pool approaches, metal‐ /organo‐catalysis, and emerging biocatalytic strategies. Enantiomerically pure α‐/β‐/γ‐thiocarboxylic acids bearing a stereocentre at
Jingyue Wu, Daniele Castagnolo
wiley   +1 more source

Bilayer Paper‐Gelatin Films With Modified Curcumin for Sustainable Packaging Applications

Polymers for Advanced Technologies, Volume 36, Issue 9, September 2025.
ABSTRACT Paper is a sustainable, cost‐effective, and versatile material broadly used in packaging applications. However, this material has poor barrier properties to water and oxygen, as well as high water sensitivity, limiting its food packaging application.
Kennya Thayres dos Santos Lima, Jéssica de Matos Fonseca, Alcilene Rodrigues Monteiro, Germán Ayala Valencia   +3 more
wiley   +1 more source

3-(2-Aminophenyl)-4-methyl-1,3-thiazole-2(3H)-thione as an Ecofriendly Sulphur Transfer Agent to Prepare Alkanethiols in High Yield and High Purity

Molecules, 2009
A new process is described for preparing very pure linear alkanethiols and linear α,ω-alkanedithiols using a sequential alkylation of the title compound, followed by a ring closure to quantitatively give the corresponding 3-methyl[1,3]thiazolo[3,2-a]-[3 ...
Federico Andreoli, Mohammed Amine Mehdid, Christian Roussel, Ayada Djafri   +3 more
doaj   +1 more source

An Evolutionarily Threat-Relevant Odor Strengthens Human Fear Memory

Frontiers in Neuroscience, 2020
Olfaction is an evolutionary ancient sense, but it remains unclear to what extent it can influence routine human behavior. We examined whether a threat-relevant predator odor (2-methyl-2-thiazoline) would contextually enhance the formation of human fear ...
Jessica E. Taylor, Hakwan Lau, Hakwan Lau, Hakwan Lau, Ben Seymour, Ben Seymour, Ben Seymour, Aya Nakae, Hidenobu Sumioka, Mitsuo Kawato, Mitsuo Kawato, Ai Koizumi, Ai Koizumi, Ai Koizumi   +13 more
doaj   +1 more source

Photophysics, pH Sensing and Hydrolysis Study of a Novel 1,8-Naphthalimide Derivative

Journal of the Turkish Chemical Society, Section A: Chemistry, 2018
In this study, a novel highly emissive compound was synthesized via two steps synthetic procedure and characterized by 1H-NMR, 13C-NMR and FTIR. Then its photophysical properties, pH sensing behaviours and pH-dependent hydrolysis were systematically ...
Alparslan Atahan, Ersin Orhan
doaj   +1 more source

Solvent‐ and Transition Metal‐Free Mechanochemical Synthesis of 2‐Thiazolines and S‐Thiocarbamates

Advanced Synthesis &Catalysis, Volume 367, Issue 14, July 29, 2025.
Solvent‐ and transition metal‐free synthetic pathways for obtaining 2‐thiazolines and S‐thiocarbamates, based on the mechanochemical process of addition of chloroalkyl iso(thio)cyanates to thiols catalyzed by cheap and commercially available K2CO3, are designed and optimized.
Kamil Hanek, Natalia Pietras, Dawid Frąckowiak, Patrycja Żak   +3 more
wiley   +1 more source

Melatonin Derivative-Conjugated Formulations of Pd(II) and Pt(II) Thiazoline Complexes on Mesoporous Silica to Enhance Cytotoxicity and Apoptosis against HeLa Cells

Pharmaceutics
The search for alternatives to cisplatin has led to the development of new metal complexes where thiazoline derivatives based on platinum(II) and palladium(II) stand out.
Samuel Estirado, Diana Díaz-García, Elena Fernández-Delgado, Emilio Viñuelas-Zahínos, Santiago Gómez-Ruiz, Sanjiv Prashar, Ana B. Rodríguez, Francisco Luna-Giles, José A. Pariente, Javier Espino   +9 more
doaj   +1 more source

Synthesis, Characterization, and Cytotoxicity of Photochromic Molybdenum Oxide‐Doped Tungsten Oxide Polymeric Nanohybrid Films for Biomedical Applications

ChemPhysChem, Volume 26, Issue 12, June 23, 2025.
A novel and environmentally friendly photosensitive nanohybrid film made of chitosan and WO3MoO3 nanoparticles is prepared via a deep eutectic solvent‐assisted hydrothermal‐based method and a solvent casting protocol. The nanocomposite film shows a strong antibacterial effect on gram‐positive and gram‐negative cells, displaying cell viability above 90%
Shephrah Olubusola Ogungbesan, Chao Zhou, Mulenga Kalulu, Oluwaseun Hannah Anselm, Adeyemi Lawrence Ogunneye, Rosemary Anwuli Adedokun, David Díaz Díaz, Guodong Fu   +7 more
wiley   +1 more source

Synthesis, Characterization and Antimicrobial Screening of Some Bioactive 1,8-Naphthalimide Derivatives.

Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2014
This research include developing new heterocyclic derivatives of 1,8-naphthalimides bearing oxazoline, thiazoline, oxadiazole, thiadiazole and aminotriazole moieties as the following steps: N-ester-1,8-naphthalimide (1) was obtained by direct imidation ...
Ayad Kareem Khan, Suaad Mohammed Hussain, Mohammed Rifat Ahmad, Fitua Manwar Aziz, Shimaa Mutasim Abdulah***   +4 more
doaj   +1 more source