Results 51 to 60 of about 733,949 (305)

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Bending of a circular disk: from cylinder to ultrathin membrane

Вестник Самарского университета: Естественнонаучная серия, 2023
The article discusses methods of mathematical modeling of the stress-strain state of a circular disc at various ratios of its thickness to radius, ranging from 1 to 10−3.
Sergey A. Lychev, Alexander V. Digilov, Nikita A. Pivovaroff   +2 more
doaj   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

A new locking-free polygonal plate element for thin and thick plates based on Reissner-Mindlin plate theory and assumed shear strain fields

, 2018
A new $n-$ noded polygonal plate element is proposed for the analysis of plate structures comprising of thin and thick members. The formulation is based on the discrete Kirchhoff Mindlin theory.
Bordas, Stephane PA, Natarajan, Sundararajan, Videla, Javier   +2 more
core   +1 more source

Multilayered plating thickness measurement [PDF]

, 1977
A nondestructive method for measuring multilayered plating thickness has been developed utilizing intensity measurements made with an x-ray fluorescence spectrometer. A series of multilayered platings was fabricated, and the thickness of each was determined through the use of a Link gage block interferometer.
openaire   +2 more sources

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

FEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold, Janik Riese, Lancelot Seillier, Mark Kühnel, Julia Pannhausen, Charlotte O. J. Fröhlich, Christian Martin, Peter Boor, Matthias Saar, Danny D. Jonigk, Nadine T. Gaisa, Michael Rose   +11 more
wiley   +1 more source

Linear to Circular Polarisation Conversion using Birefringent Properties of Aligned Crystals for Multi-GeV Photons [PDF]

, 2003
We present the first experimental results on the use of a thick aligned Si crystal acting as a quarter wave plate to induce a degree of circular polarisation in a high energy linearly polarised photon beam.
Apyan, A., Avakian, R. O., Badelek, B., Ballestrero, S., Biino, C., Birol, I., Cenci, P., Connell, S. H., Eichblatt, S., Fonseca, T., Freund, A., Gorini, B., Groess, R., Ispirian, K., Ketel, T. J., Kononets, Yu. V., Lopez, A., Mangiarotti, A., NA59 Collaboration, Sellschop, J. P. F., Shieh, M., Sona, P., Strakhovenko, V., Uggerhoj, E., Uggerhoj, U. I., Unel, G., van Rens, B., Velasco, M., Vilakazi, Z. Z., Wessely, O.   +29 more
core   +1 more source

Mapping the Asymmetric Thick Disk: The Hercules Thick Disk Cloud

, 2008
The stellar asymmetry of faint thick disk/inner halo stars in the first quadrant first reported by Larsen & Humphreys (1996) and investigated further by Parker et al. (2003, 2004) has been recently confirmed by SDSS (Juric et al. 2008).
Abadi, Belokurov, Jeffrey A. Larsen, Juan E. Cabanela, Jurić, Larsen, Larsen, Parker, Parker, Roberta M. Humphreys, Schlegel   +10 more
core   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Design of an Automated Ultrasonic Scanning System for In-Situ Composite Cure Monitoring and Defect Detection [PDF]

The preliminary design and development of an automated ultrasonic scanning system for in-situ composite cure monitoring and defect detection in the high temperature environment of an oven was completed.
Abbott, T. Bryce, Burke, Eric R., Hudson, Tyler B., Palmieri, Frank L., Seebo, Jeffrey P.   +4 more
core   +2 more sources