Results 31 to 40 of about 1,188,283 (282)
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
Polish Maritime Research, 2015 Thin and thick plates, plates with holes, stiffened panels and stiffened panels with holes are primary structural members in almost all fields of engineering: civil, mechanical, aerospace, naval, ocean etc. In this paper, a simple and efficient procedure
Cho Dae Seung +2 more
doaj +1 more source
Chiral separation of chloroalkanes with the chromatographic column onboard Martian rovers
FEBS Letters, EarlyView.Computer image of the Rosalind Franklin Rover of ESA's ExoMars mission. ExoMars is scheduled to land on planet Mars in Oxia Planum in 2029. This area represents an interesting spot to look for biosignatures. Investigations of ExoMars include measurement on molecular chirality. We show that chiral chloroalkanes, that have been identified on Mars, can be
Asma Merzougui +4 more
wiley +1 more source
Zhongguo Jianchuan YanjiuObjectivesTo solve the problem of applying thick carbon fiber laminates in naval architecture and marine engineering, this paper proposes a thick plate structure composed of thin carbon fiber laminates with reinforcing ribs and core material in the ...
Hao TONG, Yuchao YUAN, Wenyong TANG
doaj +1 more source
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Arid Zone Journal of Engineering, Technology and Environment, 2021 This study presents the application of a new refined plate theory in the bending analysis of a thick rectangular plate carrying a uniformly distributed load using the direct energy method.
F. C. Onyeka, T. E. Okeke
doaj
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
A new finite element formulation for vibration analysis of thick plates
International Journal of Naval Architecture and Ocean Engineering, 2015 A new procedure for determining properties of thick plate finite elements, based on the modified Mindlin theory for moderately thick plate, is presented.
Ivo Senjanović +2 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
ANALYSIS OF BENDING OF THICK RECTANGULAR PLATES: A REVIEW
Academy Journal of Science and EngineeringThick rectangular plates are widely used in engineering, and it is crucial for engineers to analyze their structural behavior under bending for improved design and construction.
Uchechi Eziefula +3 more
doaj +1 more source