Results 41 to 50 of about 190,891 (262)
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
FEBS Open Bio, EarlyView.Abruptly changing from aerobic to anaerobic conditions (sudden anaerobization) induced growth inhibition and a significant increase in intracellular labile ferrous iron in the aerotolerant anaerobe Amphibacillus xylanus. We found that free flavins mediate efficient electron transfer from NADH to ferric iron under anaerobic conditions, suggesting that ...
Shinya Kimata +13 more
wiley +1 more source
A higher order triangular plate finite element using Airy functions
Advances in Mechanical Engineering, 2020 The present paper describes the formulation of a new moderately thick plate bending triangular finite element based on Mindlin–Reissner plate theory. It is called a Great Triangular Moderately Thick Plate Finite Element, or GTMTPFE.
Mohammed Himeur +2 more
doaj +1 more source
Free Vibration Analysis of Thick Rectangular and Elliptical Plates with Concentric Cut-Out
Advances in Materials Science and Engineering, 2021 This research paper deals with a numerical method which is modified and applied, by the authors to derive an eigenvalue of a thick plate having cut-out in which geometries of plate and cut-outs are different, through a deflection matching condition by ...
Anjibabu Merneedi +4 more
doaj +1 more source
The effective thickness of laminated glass plates [PDF]
Journal of Mechanics of Materials and Structures, 2012 The flexural performance of laminated glass, a composite of two or more glass plies bonded together by polymeric interlayers, depends upon shear coupling between the glass components through the polymer. This effect is usually taken into account, in the design practice, through the definition of the effective thickness, i.e., the thickness of a ...
GALUPPI, Laura, ROYER CARFAGNI, Gianni
openaire +3 more sources
FEBS Open Bio, EarlyView.TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose +9 more
wiley +1 more source
FEBS Open Bio, EarlyView.Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
FEBS Open Bio, EarlyView.Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas +6 more
wiley +1 more source
Analytical formulation of hybrid-Trefftz thick plate elements
Computer Assisted Methods in Engineering and Science, 2023 This paper discusses a domain-based formulation for hybrid-Trefftz thick plate elements. The formulation can be applied to triangular and quadrilateral elements, and enables an analytical formulation of these elements to be used.
J. Petrolito
doaj
Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection
FEBS Open Bio, EarlyView.Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow +12 more
wiley +1 more source