The Biosynthesis of cis-Carbapenems and the Development of Penem Antibiotics for the Treatment of Tuberculosis [PDF]
Inspired by their naturally occurring members, the carbapenem class of β-lactam antibiotics have been heavily researched over the past forty years, resulting in the development of a set of broad-spectrum, β-lactamase resistant, last resort antibiotics ...
Lloyd, Evan Phillip
core
Topical immunotherapy for Pseudomonas keratitis : use of antilipopolyssacharide plasma [PDF]
Pseudomonas aeruginosa is an opportunistic pathogen capable of infecting the human cornea. Such infections are difficult to treat, and are often fulminative, in that the infected eye is lost, or severely scarred. The use of alternative therapeutic agents
Rauch, Andrew Johan
core +1 more source
beta-Lactams From Functionalised (Allenylmethyl)silanes [PDF]
Not ...
Rowden, Janette Yvonne
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Isolation and identification of Beta-Lactam Producing Microorganisms using PCR based methodologies [PDF]
The polymerase chain reaction (PCR) was investigated as a potential tool in microbial screening for 13-lactam. producing organisms. Optimization of PCR conditions and the addition of acetamide to the PCR reaction allowed for the successful amplification ...
Krallis, Myrsini
core +1 more source
Isolation and characterization of antibiotic(s) produced by bacteria from KwaZulu-Natal soils. [PDF]
Thesis (Ph.D.)-University of KwaZulu-Natal, Pietermaritzburg, 2010.This work reports the continued search for new antibiotics in the relatively under investigated region of KwaZulu-Natal, South Africa.
Okudoh, Vincent Ifeanyi.
core
The development of novel solid phase methodologies for the synthesis of atypical peptides and non-peptide entities [PDF]
Solid phase peptide synthesis (SPPS) of branched/cyclic peptides, multiple antigenic peptides (MAPs), pseudopeptide toxins etc. requires amine protection orthogonal to the established Fmoc/Boc protocols. It was envisaged that progression from Dde to N-1-(
Kellam, Barrie
core
Efficacy of Omadacycline-Containing Regimen in a Mouse Model of Pulmonary Mycobacteroides abscessus Disease. [PDF]
Rimal B +8 more
europepmc +1 more source
Low levels of the second messenger c-di-GMP enhance tolerance and resistance to meropenem in <i>Pseudomonas aeruginosa</i>. [PDF]
Brignoli T +3 more
europepmc +1 more source
Peritoneal histopathological changes and cultures after autogenous fecal peritonitis induced in elderly rat model: response to intravenous use of meropenem and intra-abdominal inoculation of 10% aqueous extract of Schinus Terebinthifolius Raddi (Anacardiaceae). [PDF]
Figueiredo Filho CA +6 more
europepmc +1 more source
Intravenous meropenem and intraperitoneal use of 10% aqueous extract of Schinus terebinthifolius Raddi (Anacardiaceae) in elderly rats after induction of autogenous fecal peritonitis. [PDF]
Figueiredo Filho CA +5 more
europepmc +1 more source

