A Correlative SICM‐OPM Platform for Surface and Volumetric Imaging in Live Cells
A multifunctional correlative imaging platform integrating Scanning Ion Conductance Microscopy (SICM) with Oblique Plane Microscopy (OPM) enables simultaneous surface topography, mechanical mapping, and 3D volumetric fluorescence imaging in live cells.
Wenzhi Hong +13 more
wiley +1 more source
Secreted Nonstructural Protein 3 is a Pathogenic Determinant of Orbivirus
This study uncovers a conserved PIP2‐dependent secretory pathway of orbivirus NS3 that induces vascular leakage. Pharmacological disruption of PIP2‐NS3 interaction significantly reduces viral pathogenicity and provides protective efficacy in murine models, establishing PIP2‐mediated NS3 secretion as both a key virulence determinant and a promising ...
Junyong Guan +11 more
wiley +1 more source
Optimization of SWCNT‐FET Biosensors by Aptamer Engineering and Toehold‐Mediated Strand Displacement
Aptamer‐based single‐walled carbon nanotube (SWCNT) field‐effect transistor (FET) biosensors are developed for label‐free, real‐time biomarker detection. Truncated DNA aptamers enhance sensitivity through improved conformational switching. A toehold‐mediated strand displacement (TMSD) strategy optimizes functionalization and simplifies fabrication. The
Haosen Miao +8 more
wiley +1 more source
Biosynthesis of Sciadonic Acid Derived from Gymnosperms with Anti‐Colitis Activity
This study establishes an efficient Yarrowia lipolytica platform for unusual sciadonic acid (SCA) production and assess the anti‐colitis efficacy in mice of SCA, supporting its potential as a novel therapeutic lipid. ABSTRACT Sciadonic acid (SCA), Δ5‐unsaturated fatty acid with anti‐inflammatory and lipid‐regulatory properties, is predominantly derived
Yadi Gao +10 more
wiley +1 more source
A Portable and Dual‐Button Microneedle Device Enables Intelligent Multimodal Laser Sensing
A portable and dual‐button microneedle device enables rapid interstitial fluid sampling. Coupled with multimodal laser sensing and AI‐assisted data processing, the platform enables simultaneous molecular and elemental analysis for minimally invasive and multiplexed health assessment toward point‐of‐care diagnostics.
Yuanchao Liu +12 more
wiley +1 more source
Eco-Friendly High-Performance Thin-Layer Chromatography Method for the Determination of Tenoxicam in Commercial Formulations. [PDF]
Shakeel F, Alam P, Haq N, Alqarni MH.
europepmc +1 more source
A mechanically adaptive polyimide interface dynamically stabilizes single‐crystal cathodes in sulfide all‐solid‐state batteries. By integrating robust chemical coordination with viscoelastic compliance, this smart coating suppresses parasitic reactions and accommodates cyclic volume expansion.
Jiatao Wu +8 more
wiley +1 more source
Capacitive Pixelated CMOS Electronic Nose
A 1024‐pixel CMOS capacitive E‐nose with inkjet‐printed MOFs and polymer layers yields gas‐specific capacitance fingerprints under humid conditions, discriminating toluene from 2‐butanone at low power. ABSTRACT Although some of the human senses can nowadays be replaced by low‐cost electronic sensors such as microphones and image sensors, a compact low ...
M. A. Basyooni‐M. Kabatas +7 more
wiley +1 more source
Development of a radio thin-layer chromatography scanner: Design and qualification. [PDF]
Chivato Martín-Falquina T +3 more
europepmc +1 more source
Self‐Adhesive Conductive Elastomers for Gel‐Free Biopotential Recording
σPOMaC, a self‐adhesive conductive citrate elastomer incorporating PEDOT:PSS and DBSA, enables gel‐free biopotential electrodes with stable conductivity and intrinsic skin adhesion. The composite exhibits low resistivity (∼ 0.02 Ω·cm), robust electrical performance during repeated use, and reliable on‐body ECG acquisition comparable to Ag/AgCl ...
Kirstie M. K. Queener +7 more
wiley +1 more source

