Results 121 to 130 of about 5,308,961 (383)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Increasing momentum in prevention of mental illness and mental health promotion across Europe
BJPsych International, 2016 Prevention of mental illness and mental health promotion activities across Europe have gathered some pace since the launch of the European Union's Pact for Mental Health and Well-Being in 2008. Within the context of a large treatment gap in mental health
Chiara Samele
doaj +1 more source
Scientific Thinking Skills: Why Junior High School Science Teachers Cannot Use Discovery and Inquiry Models In Classroom [PDF]
, 2018 Erman Erman +3 more
openalex +1 more source
(WP 2011-02) The Change in Sraffa\u27s Philosophical Thinking [PDF]
, 2011 The availability of Piero Sraffa’s unpublished manuscripts and correspondence at Trinity College Library, Cambridge, has made it possible to begin to set out a more complete account of Sraffa’s philosophical thinking than previously could be done with ...
Davis, John
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
, 2009 {Excerpt} Mind maps are a visual means that represent, link, and arrange concepts, themes, or tasks, with connections usually extending radially from a central topic.
Serrat, Olivier
core +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Pre-service Middle School Teachers’ Knowledge of Algebraic Thinking [PDF]
, 2010 In this study we examined the relationship between 18 pre-service middle school teachers’ own ability to use algebraic thinking to solve problems and their ability to recognize and interpret the algebraic thinking of middle school students.
Magiera, Marta +2 more
core +1 more source
Sociohydrologic Systems Thinking: An Analysis of Undergraduate Students’ Operationalization and Modeling of Coupled Human-Water Systems [PDF]
, 2020 One of the keys to science and environmental literacy is systems thinking. Learning how to think about the interactions between systems, the far-reaching effects of a system, and the dynamic nature of systems are all critical outcomes of science learning.
Forbes, Cory T., Lally, Diane
core +1 more source