Results 61 to 70 of about 1,125,240 (316)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
, 2019 Design thinking is lauded to reduce cost and redesign work in the new product development process and shorten lead time to development. Because of that, researchers are investigating how to use using design thinking as an organisational resource to ...
de Paula, Danielly
core +1 more source
Cliopsy, 2011 En juxtaposant les réflexions de Bion et d’Arendt sur la “pensée” en tant qu’activité provoquée par l’expérience, l’article interroge les conditions requises pour l’ouverture aux différences dans les situations nouvelles rencontrées. De manières très différentes, les deux théoriciens mettent en lumière comment la pensée s’appuie sur certaines ...
openaire +1 more source
Quadruple Thinking: Creative Thinking
Procedia - Social and Behavioral Sciences, 2011 AbstractIn this study, creative thinking from quadruple thinking (critical, creative, caring and hopeful thinking ways) is discussed. It is given the etymology of the term, history of creativity thought, its dimensions and the supporting thinking ways. Besides, the creative thinking is compared with uncreative thinking.
Bacanli H. +3 more
openaire +2 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
, 2022 Design thinking affect us humans in different ways every day. It is a creative approach that builds on design methods and can be implemented for anything from visuals, objects, services, systems, and environment to solve complex problems.
Wikberg Nilsson, Åsa,
core
Cómo establecer la preferencia de marca
Cuadernos Latinoamericanos de AdministraciónIntroducción: En este estudio se emplea el análisis de la presencia de la onda P300 en combinación con la asimetría frontal y el eye tracking, ampliamente utilizado en neurociencia del consumidor para analizar procesos de toma de decisiones, memoria y ...
César Augusto Salazar Olarte
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
The Nature of Design Thinking [PDF]
, 2010 In the last few years, 'Design Thinking' has gained popularity - it is now seen as an exciting new paradigm for dealing with problems in sectors as a far afield as IT, Business, Education and Medicine.
Kees Dorst, Dorst, K
core