Results 61 to 70 of about 485,373 (268)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Cómo establecer la preferencia de marca

Cuadernos Latinoamericanos de Administración
Introducción: En este estudio se emplea el análisis de la presencia de la onda P300 en combinación con la asimetría frontal y el eye tracking, ampliamente utilizado en  neurociencia del consumidor para analizar procesos de toma de decisiones, memoria y ...
César Augusto Salazar Olarte
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

A decade of dengue disease burden in Africa (2013–2023): a systematic review

Travel Medicine and Infectious Disease
Background: Dengue is a major mosquito-borne disease worldwide. The epidemiological trends of the disease in Africa over the past decade remain unclear. This review aims to provide insight into the epidemiological trends of dengue in Africa from 2013 to ...
Gaspary O. Mwanyika, Monika Moir, Abdualmoniem O. Musa, Jenicca Poongavanan, Graeme Dor, Eduan Wilkinson, Cheryl Baxter, Tulio de Oliveira, Houriiyah Tegally   +8 more
doaj   +1 more source

Thinking about Thinking as Rational Computation

, 2023
Theory of Mind enables us to attribute mental states to others. But we not only make inferences about mental states (like what someone believes or wants), but about mental processes (like if someone is distracted or whether they remember something). Here, we present a computational formalization of these kinds of inferences.
Marlene Berke, Abigail Tenenbaum, Ben Sterling, Julian Jara-Ettinger   +3 more
openaire   +2 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Why does the size of the government increase with economic development: A theory based on higher household leisure and its prediction of bigger government in the AI era

Journal of Government and Economics
It is a widely observed fact that after industrialization, the size of the government has increased significantly. This is often referred to as Wagner’s Law. Since the early twentieth century, it grew from around 10% to the current global average of 35%.
Bing Li, Daokui Li, Keaobo Li
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source

Quadruple Thinking: Critical Thinking

Procedia - Social and Behavioral Sciences, 2011
AbstractIn this study, critical thinking from quadruple thinking (caring, creative and hopeful thinking ways) is discussed. The etymology of the term, history of critical thinking, its dimensions and the supporting thinking ways are given in the study. Besides, the creative thinking is compared with nonjudgmental thinking.
Demir M., Bacanli H., Tarhan S., Ali Dombayci M.   +3 more
openaire   +3 more sources

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source