Results 51 to 60 of about 485,373 (268)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

A quantum leaky integrate-and-fire spiking neuron and network

open access: yesnpj Quantum Information
Quantum machine learning is in a period of rapid development and discovery, however it still lacks the resources and diversity of computational models of its classical complement.
Dean Brand, Francesco Petruccione
doaj   +1 more source

Detecting Location Shifts during Model Selection by Step-Indicator Saturation

open access: yesEconometrics, 2015
To capture location shifts in the context of model selection, we propose selecting significant step indicators from a saturating set added to the union of all of the candidate variables.
Jennifer L. Castle   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The impact of the cost-of-living crisis on population health in the UK: rapid evidence review

open access: yesBMC Public Health
Background In the UK, unique and unforeseen factors, including COVID-19, Brexit, and Ukraine-Russia war, have resulted in an unprecedented cost of living crisis, creating a second health emergency.
Jade Meadows   +8 more
doaj   +1 more source

To Think or Not to Think

open access: yesCliopsy, 2011
En juxtaposant les réflexions de Bion et d’Arendt sur la “pensée” en tant qu’activité provoquée par l’expérience, l’article interroge les conditions requises pour l’ouverture aux différences dans les situations nouvelles rencontrées. De manières très différentes, les deux théoriciens mettent en lumière comment la pensée s’appuie sur certaines ...
openaire   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

New Khmer Architecture: Iconic vernacular buildings under threat? [PDF]

open access: yesPacific Geographies, 2017
New Khmer Architecture (NKA) is an architecture style from Cambodia combining modernism with elements of traditional Khmer culture thereby incorporating aspects of vernacular design.
Bodach, Susanne, Waibel, Michael
doaj  

Thinking about the un-thinking [PDF]

open access: yesAdvances in Health Sciences Education, 2015
This issue could almost lay claim to being a special issue about all those things that aren’t supposed to matter in learning but do. Although emotions and interpersonal skills have been recognized as an essential component of competence for any health professional, they are rarely integrated into an overall perspective on the what and how of learning ...
openaire   +2 more sources

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