Results 41 to 50 of about 1,201,834 (278)

Classical Complement Pathway Inhibition in a Pediatric Patient With Refractory Immune Thrombocytopenia

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric refractory immune thrombocytopenia (rITP) is generally characterized by persistent thrombocytopenia and failure to achieve a sustained response to multiple standard therapies. We report a 4‐year‐old female with congenital tufting enteropathy, post‐intestinal transplant patient on immunosuppressants, who developed severe rITP ...
Sarah Hsieh   +4 more
wiley   +1 more source

Ethnographic study of ICT-supported collaborative work routines in general practice [PDF]

open access: yes, 2010
Background Health informatics research has traditionally been dominated by experimental and quasi-experimental designs. An emerging area of study in organisational sociology is routinisation (how collaborative work practices become business-as-usual ...
Trisha Greenhalgh   +13 more
core   +2 more sources

BASIC THINKING SYSTEM [PDF]

open access: yes, 2021
Thinking systematically (systematic thinking), means thinking about everything based on a certain method framework, there is a sequence and decision-making process. This requires obedience and discipline to the process and method to be used.
Nasution, Mayurida; North Sumatra State Islamic University
core   +1 more source

Effectiveness of Resistance Intradialytic Exercise Compared to Aerobic Intradialytic Exercise for Patients With Chronic Kidney Disease: A Randomized Controlled Clinical Trial

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Patients with chronic kidney disease undergoing hemodialysis commonly experience reduced physical function, fatigue, poor sleep quality, and impaired health‐related quality of life. Intradialytic exercise has been proposed as a non‐pharmacological strategy to improve these outcomes.
Klebson da Silva Almeida   +6 more
wiley   +1 more source

Using Thinking Routines To Improve The Reading And Writing Skills Of Elementary Students [PDF]

open access: yes, 2022
Developing thinking skills in teaching and learning, including English lessons, is prominent. Reading and writing are the ability that requires synthesis and higherorder thinking skills.
Manurung, Mala Rejeki; Educational Technology Programme, Universitas Negeri Surabaya   +2 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Book Review: Making Thinking Visible

open access: yesCanadian Medical Education Journal, 2015
Recent trends in medical education emphasize the importance of producing well-rounded graduates who not only possess a sufficient fund of medical knowledge but who can think clearly and deeply.
Kenneth Royal, Lizette Hardie
doaj  

Journalistic “Innovation” Is Hard to Hate, but Actual Change Is Just Hard

open access: yesMedia and Communication
Who is opposed to “innovation”? For most newsroom publishers, managers, editors, and reporters, the word connotes progress; it implies a strategy for achieving success—and dodging failure.
Jane B. Singer
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Leveraging climate resilience capacities by (un)learning from transdisciplinary research projects

open access: yesClimate Risk Management
Climate adaptation in Europe faces a significant implementation gap: while high-level policies set ambitious resilience goals, local knowledge integration and policy uptake remain slow due to entrenched institutional routines.
Simona Pedde   +5 more
doaj   +1 more source

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