Results 171 to 180 of about 3,024,368 (359)
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Raw Materials for a Learning Package about Practicing Thinking Skills
, 2010 A learning activity about the use of parallel thinking using De Bono’s 6 thinking ...
EVOLVE, UCLAN, Philippa Goldsmith
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Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
, 2014 This study examined student teacher and lecturer perceptions of the use of asynchronous discussion forums, quizzes and uploaded resources for promoting critical thinking within a pre-service teacher education programme in Tanzania.
Mwalongo, Alcuin Ivor
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, 2012 Araştırmanın amacı, Robert Sternberg’in Başarılı Zekâ Kuramı’na dayalı düşünme becerileri eğitimi programının okul öncesi öğretmen adaylarının yaratıcı düşünme becerilerine etkisini belirlemektir. Araştırmada yarı-deneysel desen kullanılmıştır. Araştırma grubu; eğitim grubu (n=34), Karşılaştırma 1 grubu (n=34), Karşılaştırma 2 grubu (n=33) olarak ...
Tok, Emel, Sevinç, M.
openaire +3 more sources
Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control
FEBS Open Bio, EarlyView.Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada +5 more
wiley +1 more source
Promoting computational thinking with programming
The term computational thinking has received some discussion in the field of computer science education research. The term is defined as the concept of thinking about problems in a way that can be implemented in a computing device.
Selby, Cynthia
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PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
Developing Mathematical Reflektive Thinki NG Skills Through Problem Based Learning
, 2011 Reflective thinking gives the opportunity to students the chance to assess believe. That means providing relevant information on the student’s belief and reflecting students' understanding of a given topic.
Lia , Kurniawati
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